Isoflurane impairs odour discrimination learning in rats: Differential effects on short- and long-term memory

British Journal of Anaesthesia

Volumn 108, Issue 4, 2012, Pages 630-637

  Pearce, R A ^a   Duscher, P ^a,b   Van Dyke, K ^a   Lee, M ^a,c   Andrei, A C ^a,d   Perouansky, M ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b Theda Clark Medical Center   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

amnesia, anterograde; anaesthetics, general; anaesthetics, inhalation; memory, long term; memory, short term

Indexed keywords

ISOFLURANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; INSTRUMENTAL CONDITIONING; LONG TERM MEMORY; MALE; NONHUMAN; OLFACTORY DISCRIMINATION; OLFACTORY MEMORY; PRIORITY JOURNAL; RAT; SHORT TERM MEMORY; TASK PERFORMANCE;

EID: 84863351079     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aer451     Document Type: Article

References (28)

1. Perouansky M, Rau V, Ford T, et al. Slowing of the hippocampal theta rhythm correlates with anesthetic-induced amnesia. Anesthesiology 2010; 113: 1299-309
2. Dutton RC, Maurer AJ, Sonner JM, Fanselow MS, Laster MJ, Eger EI II. The concentration of isoflurane required to suppress learning depends on the type of learning. Anesthesiology 2001; 94: 514-9
3. Dutton RC, Maurer AJ, Sonner JM, Fanselow MS, Laster MJ, Eger EI II. Short-term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane (2N) more than long-term memory. Anesth Analg 2002; 94: 631-9
4. Alkire MT, Gorski LA. Relative amnesic potency of five inhalational anesthetics follows the Meyer-Overton rule. Anesthesiology 2004; 101: 417-29
5. Pryor KO, Reinsel RA, Mehta M, Li Y, Wixted JT, Veselis RA. Visual P2-N2 complex and arousal at the time of encoding predict the time domain characteristics of amnesia for multiple intravenous anesthetic drugs in humans. Anesthesiology 2010; 113: 313-26
6. Veselis RA, Pryor KO, Reinsel RA, Li Y, Mehta M, Johnson R Jr. Propofol and midazolam inhibit conscious memory processes very soon after encoding: An event-related potential study of familiarity and recollection in volunteers. Anesthesiology 2009; 110: 295-312
7. Kandel L, Chortkoff BS, Sonner J, Laster MJ, Eger EI II. Nonanesthetics can suppress learning. Anesth Analg 1996; 82: 321-6
8. Rudolph U, Crestani F, Benke D, et al. Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. Nature 1999; 401: 796-800
9. Chortkoff BS, Bennett HL, Eger EI II. Subanesthetic concentrations of isoflurane suppress learning as defined by the category-example task. Anesthesiology 1993; 79: 16-22
10. Veselis RA, Reinsel RA, Feshchenko VA, Johnson R Jr. Information loss over time defines the memory defect of propofol: A comparative response with thiopental and dexmedetomidine. Anesthesiology 2004; 101: 831-41
11. Dobrunz UE, Jaeger K, Vetter G. Memory priming during light anaesthesia with desflurane and remifentanil anaesthesia. Br J Anaesth 2007; 98: 491-6
12. Eichenbaum H, Fagan A, Mathews P, Cohen NJ. Hippocampal system dysfunction and odor discrimination learning in rats: Impairment or facilitation depending on representational demands. Behav Neurosci 1988; 102: 331-9
13. Eichenbaum H, Fortin NJ. Bridging the gap between brain and behavior: Cognitive and neural mechanisms of episodic memory. J Exp Anal Behav 2005; 84: 619-29
14. Alkire MT, Haier RJ, Fallon JH, Cahill L. Hippocampal, but not amygdala, activity at encoding correlates with long-term, free recall of nonemotional information. Proc Natl Acad Sci USA 1998; 95: 14506-10
15. Cahill L, McGaugh JL. Mechanisms of emotional arousal and lasting declarative memory. Trends Neurosci 1998; 21: 294-9
16. Eichenbaum H, Fagan A, Cohen NJ. Normal olfactory discrimination learning set and facilitation of reversal learning after medial-temporal damage in rats: Implications for an account of preserved learning abilities in amnesia. J Neurosci 1986; 6: 1876-84
17. Nadel L, Moscovitch M. Memory consolidation, retrograde amnesia and the hippocampal complex. Curr Opin Neurobiol 1997; 7: 217-27
18. Packard MG, McGaugh JL. Inactivation of hippocampus or caudate nucleus with lidocaine differentially affects expression of place and response learning. Neurobiol Learn Mem 1996; 65: 65-72
19. Dudchenko PA, Wood ER, Eichenbaum H. Neurotoxic hippocampal lesions have no effect on odor span and little effect on odor recognition memory but produce significant impairments on spatial span, recognition, and alternation. J Neurosci 2000; 20: 2964-77
20. Otto T, Eichenbaum H. Complementary roles of the orbital prefrontal cortex and the perirhinal-entorhinal cortices in an odorguided delayed-nonmatching-to-sample task. Behav Neurosci 1992; 106: 762-75
21. Zacny JP, Yajnik S, Lichtor JL, et al. The acute and residual effects of subanesthetic concentrations of isoflurane/nitrous oxide combinations on cognitive and psychomotor performance in healthy volunteers. Anesth Analg 1996; 82: 153-7
22. Galinkin JL, Janiszewski D, Young CJ, et al. Subjective, psychomotor, cognitive, and analgesic effects of subanesthetic concentrations of sevoflurane and nitrous oxide. Anesthesiology 1997; 87: 1082-8
23. Dwyer R, Bennett HL, Eger EI II, Heilbron D. Effects of isoflurane and nitrous oxide in subanesthetic concentrations on memory and responsiveness in volunteers. Anesthesiology 1992; 77: 888-98
24. Rabat A, Hardouin J, Courtiere A. Nitrous oxide impairs selective stages of working memory in rats. Neurosci Lett 2004; 364: 22-6
25. Burlingame RH, Shrestha S, Rummel MR, Banks MI. Subhypnotic doses of isoflurane impair auditory discrimination in rats. Anesthesiology 2007; 106: 754-62
26. Laroche S, Davis S, Jay TM. Plasticity at hippocampal to prefrontal cortex synapses: Dual roles in working memory and consolidation. Hippocampus 2000; 10: 438-46
27. Floresco S, Seamans JK, Phillips AG. Selective roles for hippocampal, prefrontal cortical, and ventral striatal circuits in radial-arm maze tasks with or without a delay. J Neurosci 1997; 17: 1880-90
28. Perouansky M, Hemmings HC Jr. Neurotoxicity of general anesthetics: Cause for concerň Anesthesiology 2009; 111: 1365-71