1H chemical shift magnetic resonance imaging probes with high sensitivity for multiplex imaging

Contrast Media and Molecular Imaging

Volumn 7, Issue 2, 2012, Pages 276-279

  Yang, Yan ^a,b   Schühle, Daniel T ^a   Dai, Guangping ^a   Alford, Jamu K ^a   Caravan, Peter ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Chemical shift imaging; Gadolinium; Multiplex

Indexed keywords

3 (2 HYDROXYETHYL)THIAZOLIUM BROMIDE; DOCUSATE SODIUM; LIPOSOME; NANOCARRIER; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; TETRAXETAN; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; PROTON;

ARTICLE; CONTRAST ENHANCEMENT; HUMAN; HUMAN CELL; NANOENCAPSULATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; UMBILICAL VEIN ENDOTHELIAL CELL; CHEMISTRY; METHODOLOGY; MOLECULAR PROBE; NUCLEAR MAGNETIC RESONANCE IMAGING; SIGNAL NOISE RATIO; SUSPENSION; TIME;

LIPOSOMES; MAGNETIC RESONANCE IMAGING; MOLECULAR PROBES; PROTONS; SIGNAL-TO-NOISE RATIO; SUSPENSIONS; TIME FACTORS;

EID: 84863350976     PISSN: 15554309     EISSN: 15554317     Source Type: Journal    
DOI: 10.1002/cmmi.490     Document Type: Article

References (20)

1. Chalmers KH, De Luca E, Hogg NHM, Kenwright AM, Kuprov I, Parker D, Botta M, Wilson JI, Blamire AM. Design principles and theory of paramagnetic fluorine-labelled lanthanide complexes as probes for F-19 magnetic resonance: a proof-of-concept study. Chem- Eur J 2010; 16(1): 134-148.
2. Aime S, Botta M, Fasano M, Terreno E, Kinchesh P, Calabi L, Paleari L. A new ytterbium chelate as contrast agent in chemical shift imaging and temperature sensitive probe for MR spectroscopy. Magn Reson Med 1996; 35(5): 648-651.
3. -). Int J Hypertherm 2002; 18(3): 165-179.
4. Provent P, Benito M, Hiba B, Farion R, Lopez-Larrubia P, Ballesteros P, Remy C, Segebarth C, Cerdan S, Coles JA, Garcia-Martin ML. Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular pH in rat gliomas shows redistribution of protons away from sites of glycolysis. Cancer Res 2007; 67(16): 7638-7645.
5. 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane. Magn Reson Med 2006; 55(4): 743-748.
6. Kodibagkar VD, Wang XH, Pacheco-Torres J, Gulaka P, Mason RP. Proton imaging of siloxanes to map tissue oxygenation levels: a tool for quantitative tissue oximetry. NMR Biomed 2008; 21(8): 899-907.
7. Fahlbusch T, Frank M, Schatz J, Schühle DT. Kinetic acidity of supramolecular imidazolium salts - effects of substituent, preorientation, and counterions on H/D exchange rates. J Org Chem 2006; 71(4): 1688-1691.
8. Aime S, Botta M, Ermondi G. NMR-study of solution structures and dynamics of lanthanide(III) complexes of DOTA. Inorg Chem 1992; 31(21): 4291-4299.
9. 1H NMR spectroscopy of rat brain at 1ms echo time. Magn Reson Med 1999; 41(4): 649-656.
10. Frahm J, Merboldt KD, Hanicke W. Localized proton spectroscopy using stimulated echoes. J Magn Reson 1987; 72(3): 502-508.
11. Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 2005; 4(2): 145-160.
12. Lasic DD, Needham D. The 'stealth' liposome: a prototypical biomaterial. Chem Rev 1995; 95(8): 2601-2628.
13. Heath TD, Fraley RT, Papahadjopoulos D. Antibody targeting of liposomes - cell specificity obtained by conjugation of F(ab')2 to vesicle surface. Science 1980; 210(4469): 539-541.
14. Lanza GM, Yu X, Winter PM, Abendschein DR, Karukstis KK, Scott MJ, Chinen LK, Fuhrhop RW, Scherrer DE, Wickline SA. Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: implications for rational therapy of restenosis. Circulation 2002; 106(22): 2842-2847.
15. Mulder WJM, Strijkers GJ, van Tilborg GAF, Griffioen AW, Nicolay K. Lipid-based nanoparticles for contrast-enhanced MRI and molecular imaging. NMR Biomed 2006; 19(1): 142-164.
16. Vucic E, Sanders HM, Arena F, Terreno E, Aime S, Nicolay K, Leupold E, Dathe M, Sommerdijk NA, Fayad ZA, Mulder WJ. Well-defined, multifunctional nanostructures of a paramagnetic lipid and a lipopeptide for macrophage imaging. J Am Chem Soc 2009; 131(2): 406-407.
17. Uppal R, Caravan P. Targeted probes for cardiovascular MR imaging. Future Med Chem 2010; 2(3): 451-470.
18. 19F signals from perfluorocarbon nanoparticles as a new strategy for molecular imaging. Magn Reson Med 2008; 60(5): 1066-1072.
19. 19F MR-imaging - relaxation enhancement with Gd-DTPA. J Magn Reson Imag 1994; 4(4): 609-613.
20. Terreno E, Castelli DD, Viale A, Aime S. Challenges for molecular magnetic resonance imaging. Chem Rev 2010; 110(5): 3019-3042.