Research on the stability of a rabbit dry eye model induced by topical application of the preservative benzalkonium chloride

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Li, Chaoyang ^a   Song, Yiyue ^a   Luan, Shaohong ^a   Wan, Pengxia ^a   Li, Naiyang ^a   Tang, Jing ^b   Han, Yu ^b   Xiong, Cuiju ^a   Wang, Zhichong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b People's Hospital of Leshan   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BENZALKONIUM CHLORIDE; EOSIN; FLUORESCEIN; HEMATOXYLIN; MUCIN 5AC; BENZALKONIUM; EYE DROPS; PRESERVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONJUNCTIVA; CONTROLLED STUDY; CORNEA; DISEASE MODEL; DRUG EFFICACY; DRY EYE; EYEBALL; FEMALE; GOBLET CELL; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMPRESSION CYTOLOGY; NONHUMAN; PROTEIN DEFICIENCY; RABBIT; SCANNING ELECTRON MICROSCOPY; SCHIRMER TEST; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT DURATION; ULTRASTRUCTURE; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; HUMAN; LACRIMAL FLUID; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SECRETION; TIME; VALIDATION STUDY;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

ANIMALS; BENZALKONIUM COMPOUNDS; CONJUNCTIVA; CORNEA; DISEASE MODELS, ANIMAL; DRY EYE SYNDROMES; FEMALE; GOBLET CELLS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MUCIN 5AC; OPHTHALMIC SOLUTIONS; PRESERVATIVES, PHARMACEUTICAL; RABBITS; TEARS; TIME FACTORS;

EID: 84863348090     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033688     Document Type: Article

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