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Volumn 303, Issue 1, 2012, Pages

BMP-2 induces a profibrotic phenotype in adult renal progenitor cells through Nox4 activation

Author keywords

DGF; NADPH oxidase; Stem cells

Indexed keywords

ACETYLCYSTEINE; ALPHA SMOOTH MUSCLE ACTIN; BASILIXIMAB; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR; CD133 ANTIGEN; COLLAGEN TYPE 1; CYCLOSPORIN A; FIBRONECTIN; HYDROGEN PEROXIDE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TACROLIMUS;

EID: 84863336505     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00328.2011     Document Type: Article
Times cited : (31)

References (33)
  • 1
    • 52649137487 scopus 로고    scopus 로고
    • Identification of renal potential progenitor/stem cells that participate in the renal regeneration processes of kidney allograft fibrosis
    • Bao J, Tu Z, Sun H, Yang L, Song J, Qin M, Shi Y, Bu H, Li Y. Identification of renal potential progenitor/stem cells that participate in the renal regeneration processes of kidney allograft fibrosis. Nephrology (Carlton) 13: 500-507, 2008.
    • (2008) Nephrology (Carlton) , vol.13 , pp. 500-507
    • Bao, J.1    Tu, Z.2    Sun, H.3    Yang, L.4    Song, J.5    Qin, M.6    Shi, Y.7    Bu, H.8    Li, Y.9
  • 3
    • 0037836057 scopus 로고    scopus 로고
    • Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure
    • Bonventre JV. Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol 14: S55-S61, 2003.
    • (2003) J Am Soc Nephrol , vol.14
    • Bonventre, J.V.1
  • 5
    • 52649170367 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling in the developing kidney: Present and future
    • Cain JE, Hartwig S, Bertram JF, Rosenblum ND. Bone morphogenetic protein signaling in the developing kidney: present and future. Differentiation 76: 831-842, 2008.
    • (2008) Differentiation , vol.76 , pp. 831-842
    • Cain, J.E.1    Hartwig, S.2    Bertram, J.F.3    Rosenblum, N.D.4
  • 6
    • 33845972599 scopus 로고    scopus 로고
    • Concise review: Bone morphogenetic protein pleiotropism in neural stem cells and their derivatives-alternative pathways, convergent signals
    • Chen HL, Panchision DM. Concise review: bone morphogenetic protein pleiotropism in neural stem cells and their derivatives-alternative pathways, convergent signals. Stem Cells 25: 63-68, 2007.
    • (2007) Stem Cells , vol.25 , pp. 63-68
    • Chen, H.L.1    Panchision, D.M.2
  • 7
    • 0344924850 scopus 로고    scopus 로고
    • Gene expression in early ischemic renal injury: Clues towards pathogenesis, biomarker discovery, and novel therapeutics
    • Devarajan P, Mishra J, Supavekin S, Patterson LT, Potterc SS. Gene expression in early ischemic renal injury: clues towards pathogenesis, biomarker discovery, and novel therapeutics. Mol Genet Metab 80: 365-376, 2003.
    • (2003) Mol Genet Metab , vol.80 , pp. 365-376
    • Devarajan, P.1    Mishra, J.2    Supavekin, S.3    Patterson, L.T.4    Potterc, S.S.5
  • 8
    • 0034840860 scopus 로고    scopus 로고
    • Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase
    • Gorin Y, Kim NH, Feliers D, Bhandari B, Choudhury GG, Abboud HE. Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase. FASEB J 15: 1909-1920, 2001.
    • (2001) FASEB J , vol.15 , pp. 1909-1920
    • Gorin, Y.1    Kim, N.H.2    Feliers, D.3    Bhandari, B.4    Choudhury, G.G.5    Abboud, H.E.6
  • 10
    • 0036149123 scopus 로고    scopus 로고
    • BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells
    • Gould SE, Day M, Jones SS, Dorai H. BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells. Kidney Int 61:51-60, 2002.
    • (2002) Kidney Int , vol.61 , pp. 51-60
    • Gould, S.E.1    Day, M.2    Jones, S.S.3    Dorai, H.4
  • 11
    • 42549151568 scopus 로고    scopus 로고
    • Increase of proliferating renal progenitor cells in acute tubular necrosis underlying delayed graft function
    • Loverre A, Capobianco C, Ditonno P, Battaglia M, Grandaliano G, Schena FP. Increase of proliferating renal progenitor cells in acute tubular necrosis underlying delayed graft function. Transplantation 85: 1112-1119, 2008.
    • (2008) Transplantation , vol.85 , pp. 1112-1119
    • Loverre, A.1    Capobianco, C.2    Ditonno, P.3    Battaglia, M.4    Grandaliano, G.5    Schena, F.P.6
  • 12
    • 31144440253 scopus 로고    scopus 로고
    • Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
    • Ma L, Lu MF, Schwartz RJ, Martin JF. Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development 132: 5601-5611, 2005.
    • (2005) Development , vol.132 , pp. 5601-5611
    • Ma, L.1    Lu, M.F.2    Schwartz, R.J.3    Martin, J.F.4
  • 13
    • 8444229815 scopus 로고    scopus 로고
    • Delayed graft function in kidney transplantation
    • Perico N, Cattaneo D, Sayegh MH, Remuzzi G. Delayed graft function in kidney transplantation. Lancet 364: 1814-1827, 2004.
    • (2004) Lancet , vol.364 , pp. 1814-1827
    • Perico, N.1    Cattaneo, D.2    Sayegh, M.H.3    Remuzzi, G.4
  • 15
    • 20544437490 scopus 로고    scopus 로고
    • Role of reactive oxygen species in TGF-_1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells
    • Rhyu DY, Yang Y, Ha H, Lee GT, Song JS, Uh St Lee HB. Role of reactive oxygen species in TGF-_1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 16: 667-675, 2005.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 667-675
    • Rhyu, D.Y.1    Yang, Y.2    Ha, H.3    Lee, G.T.4    Song, J.S.5    Uh St Lee, H.B.6
  • 16
    • 33745266407 scopus 로고    scopus 로고
    • Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field
    • Rivera-Feliciano J, Tabin CJ. Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field. Dev Biol 295: 580-588, 2006.
    • (2006) Dev Biol , vol.295 , pp. 580-588
    • Rivera-Feliciano, J.1    Tabin, C.J.2
  • 20
    • 0038300075 scopus 로고    scopus 로고
    • Effect of transforming growth factor beta and bone morphogenetic proteins on rat hepatic stellate cell proliferation and transdifferentiation
    • Shen H, Huang GJ, Gong YW. Effect of transforming growth factor beta and bone morphogenetic proteins on rat hepatic stellate cell proliferation and transdifferentiation. World J Gastroenterol 9: 784-787, 2003.
    • (2003) World J Gastroenterol , vol.9 , pp. 784-787
    • Shen, H.1    Huang, G.J.2    Gong, Y.W.3
  • 21
    • 21344443319 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in development and homeostasis of kidney
    • Simic P, Vukicevic S. Bone morphogenetic proteins in development and homeostasis of kidney. Cytokine Growth Factor Rev 16: 299-308, 2005.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 299-308
    • Simic, P.1    Vukicevic, S.2
  • 22
    • 1942425190 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice
    • Sugi Y, Yamamura H, Okagawa H, Markwald RR. Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice. Dev Biol 269: 505-518, 2004.
    • (2004) Dev Biol , vol.269 , pp. 505-518
    • Sugi, Y.1    Yamamura, H.2    Okagawa, H.3    Markwald, R.R.4
  • 23
    • 16344378397 scopus 로고    scopus 로고
    • TGF-_ and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
    • Valcourt U, Kowanetz M, Niimi H, Heldin CH, Moustakas A. TGF-_ and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol Biol Cell 16: 1987-2002, 2005.
    • (2005) Mol Biol Cell , vol.16 , pp. 1987-2002
    • Valcourt, U.1    Kowanetz, M.2    Niimi, H.3    Heldin, C.H.4    Moustakas, A.5
  • 24
    • 24644507896 scopus 로고    scopus 로고
    • The disparate role of BMP in stem cell biology
    • Varga AC, Wrana JL. The disparate role of BMP in stem cell biology. Oncogene 24: 5713-5721, 2005.
    • (2005) Oncogene , vol.24 , pp. 5713-5721
    • Varga, A.C.1    Wrana, J.L.2
  • 25
    • 33646490589 scopus 로고    scopus 로고
    • Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins
    • Villanueva S, Céspedes C, Vio CP. Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins. Am J Physiol Regul Integr Comp Physiol 290: R861-R870, 2006.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Villanueva, S.1    Céspedes, C.2    Vio, C.P.3
  • 26
    • 58149239733 scopus 로고    scopus 로고
    • Roles of TGF-_ family signaling in stem cell renewal and differentiation
    • Watabe T, Miyazono K. Roles of TGF-_ family signaling in stem cell renewal and differentiation. Cell Res 19: 103-115 2009.
    • (2009) Cell Res , vol.19 , pp. 103-115
    • Watabe, T.1    Miyazono, K.2
  • 27
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol 214: 199-210, 2008.
    • (2008) J Pathol , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 30
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9: 964-968, 2003.
    • (2003) Nat Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 31
    • 14844290237 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
    • Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J Biol Chem 280: 8094-8100, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 8094-8100
    • Zeisberg, M.1    Shah, A.A.2    Kalluri, R.3
  • 32
    • 23244432429 scopus 로고    scopus 로고
    • BMP signaling and stem cell regulation
    • Zhang J, Li L. BMP signaling and stem cell regulation. Dev Biol 284: 1-11, 2005.
    • (2005) Dev Biol , vol.284 , pp. 1-11
    • Zhang, J.1    Li, L.2
  • 33
    • 14644429806 scopus 로고    scopus 로고
    • Induction of chondro-, osteo-and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: Effect of cofactors on differentiating lineages
    • zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ. Induction of chondro-, osteo-and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: Effect of cofactors on differentiating lineages. BMC Dev Biol 5:1-12, 2005.
    • (2005) BMC Dev Biol , vol.5 , pp. 1-12
    • zur Nieden, N.I.1    Kempka, G.2    Rancourt, D.E.3    Ahr, H.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.