A polymorphism in the upstream regulatory region of the interleukin-1α gene confers differential binding by transcription factors of the AP-1 family

Life Sciences

Volumn 90, Issue 25-26, 2012, Pages 975-979

  Moerman Herzog, Andréa M ^a   Barger, Steven W ^a,b,c  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

Author keywords

Activator Protein 1; Alzheimer's disease; C Fos; C Jun; Cytokine; Inflammation; Interleukin 1; Jun N terminal kinase; Microglia; Transcription factor

Indexed keywords

INTERLEUKIN 1ALPHA; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; GENE; GENE SEQUENCE; GENETIC POLYMORPHISM; MICROGLIA; MOUSE; NONHUMAN;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; INTERLEUKIN-1ALPHA; MICROGLIA; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR AP-1;

EID: 84863332121     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.05.004     Document Type: Article

References (24)

1. D. Abazis-Stamboulieh, P. Oikonomou, N. Papadoulis, P. Panayiotidis, E. Vrakidou, and A. Tsezou Association of interleukin-1A, interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms with multiple myeloma Leuk Lymphoma 48 2007 2196 2203
2. S.W. Barger, and A.D. Harmon Microglial activation by secreted Alzheimer amyloid precursor protein and modulation by apolipoprotein E Nature 388 1997 878 881
3. S.W. Barger, M.E. Goodwin, M.M. Porter, and M.L. Beggs Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation J Neurochem 101 2007 1205 1213
4. A. Bast, K. Fischer, S.F. Erttmann, and R. Walther Induction of peroxiredoxin I gene expression by LPS involves the Src/PI3K/JNK signalling pathway Biochim Biophys Acta 1799 2010 402 410
5. O. Combarros, J. Llorca, M. Sanchez-Guerra, J. Infante, and J. Berciano Age-dependent association between interleukin-1A (- 889) genetic polymorphism and sporadic Alzheimer's disease. A meta-analysis J Neurol 250 2003 987 989
6. C.A. Cordeiro, P.R. Moreira, G.C. Costa, W.O. Dutra, W.R. Campos, and F. Orefice Interleukin-1 gene polymorphisms and toxoplasmic retinochoroiditis Mol Vis 14 2008 1845 1849
7. C.M. de Jongh, S.M. John, D.P. Bruynzeel, F. Calkoen, F.J. van Dijk, and L. Khrenova Cytokine gene polymorphisms and susceptibility to chronic irritant contact dermatitis Contact Dermatitis 58 2008 269 277
8. R. Dominici, M. Cattaneo, G. Malferrari, D. Archi, C. Mariani, and L.M. Grimaldi Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha Immunogenetics 54 2002 82 86
9. W.S. Griffin Inflammation and neurodegenerative diseases Am J Clin Nutr 83 2006 470S 474S
10. W.S. Griffin, J.G. Sheng, S.M. Gentleman, D.I. Graham, R.E. Mrak, and G.W. Roberts Microglial interleukin-1a expression in human head injury: correlations with neuronal and neuritic b-amyloid precursor protein expression Neurosci Lett 176 1994 133 136
11. R. Griffin, R. Nally, Y. Nolan, Y. McCartney, J. Linden, and M.A. Lynch The age-related attenuation in long-term potentiation is associated with microglial activation J Neurochem 99 2006 1263 1272
12. W.S. Griffin, L. Liu, Y. Li, R.E. Mrak, and S.W. Barger Interleukin-1 mediates Alzheimer and Lewy body pathologies J Neuroinflammation 3 2006 5
13. L.M. Grimaldi, V.M. Casadei, C. Ferri, F. Veglia, F. Licastro, and G. Annoni Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism Ann Neurol 47 2000 361 365
14. A. Kolbus, K. Walch, F. Nagele, R. Wenzl, G. Unfried, and J.C. Huber Interleukin-1 alpha but not interleukin-1 beta gene polymorphism is associated with polycystic ovary syndrome J Reprod Immunol 73 2007 188 193
15. K.S. Kornman Interleukin 1 genetics, inflammatory mechanisms, and nutrigenetic opportunities to modulate diseases of aging Am J Clin Nutr 83 2006 475S 483S
16. K.S. Kornman, A. Crane, H.Y. Wang, F.S. di Giovine, M.G. Newman, and F.W. Pirk The interleukin-1 genotype as a severity factor in adult periodontal disease J Clin Periodontol 24 1997 72 77
17. B. Li, C. Tournier, R.J. Davis, and R.A. Flavell Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation EMBO J 18 1999 420 432
18. Y. Li, L. Liu, J. Kang, J.G. Sheng, S.W. Barger, and R.E. Mrak Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression J Neurosci 20 2000 149 155
19. R.E. Mrak, and W.S. Griffin Glia and their cytokines in progression of neurodegeneration Neurobiol Aging 26 2005 349 354
20. J.A. Nicoll, R.E. Mrak, D.I. Graham, J. Stewart, G. Wilcock, S. MacGowan, M.M. Esiri, L.S. Murray, D. Dewar, S. Love, T. Moss, and W.S. Griffin Association of interleukin-1 gene polymorphisms with Alzheimer's disease Ann Neurol 47 2000 365 368
21. I. Rainero, M. Bo, M. Ferrero, W. Valfre, G. Vaula, and L. Pinessi Association between the interleukin-1alpha gene and Alzheimer's disease: a meta-analysis Neurobiol Aging 25 2004 1293 1298
22. G.W. Roberts, S.M. Gentleman, A. Lynch, and D.I. Graham bA4 amyloid protein deposition in brain after head injury Lancet 338 1991 1422 1423
23. A. Tsezou, L. Poultsides, F. Kostopoulou, E. Zintzaras, M. Satra, and S. Kitsiou-Tzeli Influence of interleukin 1alpha (IL-1alpha), IL-4, and IL-6 polymorphisms on genetic susceptibility to chronic osteomyelitis Clin Vaccine Immunol 15 2008 1888 1890
24. X. Wei, X. Chen, C. Fontanilla, L. Zhao, Z. Liang, and R. Dodel C/T conversion alters interleukin-1A promoter function in a human astrocyte cell line Life Sci 80 2007 1152 1156