-
1
-
-
23444461364
-
Endometrial cancer
-
Amant F, Moerman P, Neven P, et al (2005). Endometrial cancer. Lancet, 366, 491-505.
-
(2005)
Lancet
, vol.366
, pp. 491-505
-
-
Amant, F.1
Moerman, P.2
Neven, P.3
-
2
-
-
6344256753
-
MtorA protein kinase switching between life and death
-
Asnaghi L, Bruno P, Priulla M, et al (2004). MtorA protein kinase switching between life and death. Pharmacol Res, 50, 545-9.
-
(2004)
Pharmacol Res
, vol.50
, pp. 545-549
-
-
Asnaghi, L.1
Bruno, P.2
Priulla, M.3
-
3
-
-
0030220145
-
A phase II trial of paclitaxel in patients with advanced or recurrent adenocarcinoma of the endometrium: a Gynecologic Oncology Group study
-
Ball HG, Blessing JA, Lentz SS, et al (1996). A phase II trial of paclitaxel in patients with advanced or recurrent adenocarcinoma of the endometrium: a Gynecologic Oncology Group study. Gynecol Oncol, 62, 278-81.
-
(1996)
Gynecol Oncol
, vol.62
, pp. 278-281
-
-
Ball, H.G.1
Blessing, J.A.2
Lentz, S.S.3
-
4
-
-
33845227643
-
Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic,colon, and breast tumors
-
Buck E, Eyzaguirre A, Brown E, et al (2006). Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic,colon, and breast tumors. Mol Cancer Ther, 5, 2676-84.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2676-2684
-
-
Buck, E.1
Eyzaguirre, A.2
Brown, E.3
-
5
-
-
62049084546
-
Rapamycin induces transactivation of the egfr and increases cell survival
-
Chaturvedi D, Gao X, Cohen MS, et al (2009). Rapamycin induces transactivation of the egfr and increases cell survival. Oncogene, 28, 1187-96.
-
(2009)
Oncogene
, vol.28
, pp. 1187-1196
-
-
Chaturvedi, D.1
Gao, X.2
Cohen, M.S.3
-
6
-
-
33746622984
-
Strategies for optimizing combinations of molecularly targeted anticancer agents
-
Dancey JE, Chen HX (2006). Strategies for optimizing combinations of molecularly targeted anticancer agents. Nat Rev Drug Discov, 5, 649-59.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 649-659
-
-
Dancey, J.E.1
Chen, H.X.2
-
7
-
-
79955577284
-
Emerging therapeutic targets in endometrial cancer
-
Dedes KJ, Wetterskog D, Ashworth A, et al (2011). Emerging therapeutic targets in endometrial cancer. Nat Rev Clin Oncol, 8, 261-71.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 261-271
-
-
Dedes, K.J.1
Wetterskog, D.2
Ashworth, A.3
-
8
-
-
77958049428
-
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to parp inhibitors
-
Dedes KJ, Wetterskog D, Mendes-Pereira AM, et al (2010). PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to parp inhibitors. Sci Transl Med, 2, 53-75.
-
(2010)
Sci Transl Med
, vol.2
, pp. 53-75
-
-
Dedes, K.J.1
Wetterskog, D.2
Mendes-Pereira, A.M.3
-
9
-
-
50649103493
-
Phase ii study of carboplatin and erlotinib (tarcevaosi-774) in patients with recurrent glioblastoma
-
de Groot JF, Gilbert MR, Aldape K, et al (2008). Phase ii study of carboplatin and erlotinib (tarcevaosi-774) in patients with recurrent glioblastoma. Dedes KJ, 90, 89-97.
-
(2008)
Dedes KJ
, vol.90
, pp. 89-97
-
-
de Groot, J.F.1
Gilbert, M.R.2
Aldape, K.3
-
10
-
-
0027467778
-
Assembly of purified gdp-tubulin into microtubules induced by taxol and taxotere: Reversibility, ligand stoichiometry, and competition
-
Diaz JF, Andreu JM (1993). Assembly of purified gdp-tubulin into microtubules induced by taxol and taxotere: Reversibility, ligand stoichiometry, and competition. Biochemistry, 32, 2747-55.
-
(1993)
Biochemistry
, vol.32
, pp. 2747-2755
-
-
Diaz, J.F.1
Andreu, J.M.2
-
11
-
-
33746807790
-
Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas
-
Doherty L, Gigas DC, Kesari S, et al (2006). Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology, 67, 156-8.
-
(2006)
Neurology
, vol.67
, pp. 156-158
-
-
Doherty, L.1
Gigas, D.C.2
Kesari, S.3
-
12
-
-
33746637660
-
Current development of mtor inhibitors as anticancer agents
-
Faivre S, Kroemer G, Raymond E (2006). Current development of mtor inhibitors as anticancer agents. Nat Rev Drug Discov, 5, 671-88.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 671-688
-
-
Faivre, S.1
Kroemer, G.2
Raymond, E.3
-
13
-
-
23844528811
-
Inhibitors of epidermoid growth factor receptor suppress cell growth and enhance chemosensitivity of nasopharyngeal cancer cells in vitro
-
Hsu CH, Gao M, Chen CL, et al (2005). Inhibitors of epidermoid growth factor receptor suppress cell growth and enhance chemosensitivity of nasopharyngeal cancer cells in vitro. Oncology, 68, 538-47.
-
(2005)
Oncology
, vol.68
, pp. 538-547
-
-
Hsu, C.H.1
Gao, M.2
Chen, C.L.3
-
14
-
-
33847662544
-
Chemotherapy for advanced, recurrent or metastatic endometrial cancer: A systematic review of cochrane collaboration
-
Humber CE, Tierney JF, Symonds RP, et al (2007). Chemotherapy for advanced, recurrent or metastatic endometrial cancer: A systematic review of cochrane collaboration. Ann Oncol, 18, 409-20.
-
(2007)
Ann Oncol
, vol.18
, pp. 409-420
-
-
Humber, C.E.1
Tierney, J.F.2
Symonds, R.P.3
-
15
-
-
33947422073
-
Dual egfr and mtor targeting in squamous cell carcinoma models, and development of early markers of efficacy
-
Jimeno A, Kulesza P, Wheelhouse J, et al (2007). Dual egfr and mtor targeting in squamous cell carcinoma models, and development of early markers of efficacy. Br J Cancer, 96, 952-9.
-
(2007)
Br J Cancer
, vol.96
, pp. 952-959
-
-
Jimeno, A.1
Kulesza, P.2
Wheelhouse, J.3
-
16
-
-
0037342140
-
Activity of paclitaxel as second-line chemotherapy in endometrial carcinoma: a Gynecologic Oncology Group study
-
Lincoln S, Blessing JA, Lee RB, et al (2003). Activity of paclitaxel as second-line chemotherapy in endometrial carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol, 88, 277-81.
-
(2003)
Gynecol Oncol
, vol.88
, pp. 277-281
-
-
Lincoln, S.1
Blessing, J.A.2
Lee, R.B.3
-
17
-
-
34247370642
-
Combining an mtor antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer
-
Masiello D, Mohi MG, McKnight NC, et al (2007) Combining an mtor antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer. Cancer Biol Ther, 6, 195-201.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 195-201
-
-
Masiello, D.1
Mohi, M.G.2
McKnight, N.C.3
-
18
-
-
77349125856
-
Microrna-21 inhibitor sensitizes human glioblastoma cells u251 (pten-mutant) and ln229 (pten-wild type) to taxol
-
Microrna-21 inhibitor sensitizes human glioblastoma cells u251 (pten-mutant) and ln229 (pten-wild type) to taxol. BMC Cancer, 10, 27.
-
BMC Cancer
, vol.10
, pp. 27
-
-
-
19
-
-
77954313321
-
Enhancement of paclitaxel-induced apoptosis in her2-overexpressing human breast cancer cells by a pertuzumab mimetic peptidehrap
-
Nakajima H, Mizuta N, Sakaguchi K, et al (2010). Enhancement of paclitaxel-induced apoptosis in her2-overexpressing human breast cancer cells by a pertuzumab mimetic peptidehrap. J Biosci Bioeng, 110, 250-3.
-
(2010)
J Biosci Bioeng
, vol.110
, pp. 250-253
-
-
Nakajima, H.1
Mizuta, N.2
Sakaguchi, K.3
-
20
-
-
34547099558
-
Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma
-
Ollikainen M, Gylling A, Puputti M, et al (2007). Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma. International J of Cancer, 121, 915-20.
-
(2007)
International J of Cancer
, vol.121
, pp. 915-920
-
-
Ollikainen, M.1
Gylling, A.2
Puputti, M.3
-
21
-
-
52049125733
-
Phase ii study of erlotinib in recurrent or metastatic endometrial cancer: Ncic ind-148
-
Oza AM, Eisenhauer EA, Elit L, et al (2008). Phase ii study of erlotinib in recurrent or metastatic endometrial cancer: Ncic ind-148. J Clin Oncol, 26, 4319-25.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4319-4325
-
-
Oza, A.M.1
Eisenhauer, E.A.2
Elit, L.3
-
22
-
-
0030741043
-
MRNA expression of ligands of the epidermal-growth- factor- receptor in the uterus
-
Pfeiffer D, Spranger J, Al-Deiri M, et al (1997). MRNA expression of ligands of the epidermal-growth- factor- receptor in the uterus. Int J Cancer, 72, 581-6.
-
(1997)
Int J Cancer
, vol.72
, pp. 581-586
-
-
Pfeiffer, D.1
Spranger, J.2
Al-Deiri, M.3
-
23
-
-
78649592049
-
A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma
-
Slomovitz BM, Lu KH, Johnston T, et al (2010). A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma. Cancer, 116, 5415-9.
-
(2010)
Cancer
, vol.116
, pp. 5415-5419
-
-
Slomovitz, B.M.1
Lu, K.H.2
Johnston, T.3
-
24
-
-
18144399578
-
Mtor-targeted therapy of cancer with rapamycin derivatives
-
Vignot S, Faivre S, Aguirre D, et al (2005). Mtor-targeted therapy of cancer with rapamycin derivatives. Ann Oncol, 16, 525-37.
-
(2005)
Ann Oncol
, vol.16
, pp. 525-537
-
-
Vignot, S.1
Faivre, S.2
Aguirre, D.3
-
25
-
-
34248576166
-
Rapamycin together with herceptin significantly increased anti-tumor efficacy compared to either alone in erbb2 over expressing breast cancer cells
-
Wang LH, Chan JL, Li W (2007). Rapamycin together with herceptin significantly increased anti-tumor efficacy compared to either alone in erbb2 over expressing breast cancer cells. Int J Cancer, 121, 157-64.
-
(2007)
Int J Cancer
, vol.121
, pp. 157-164
-
-
Wang, L.H.1
Chan, J.L.2
Li, W.3
-
26
-
-
77958049428
-
Pten deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to parp inhibitors
-
Ren Y, Zhou X, Mei M, et al. (2010)
-
Wetterskog D, Mendes-Pereira AM, et al (2010). Pten deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to parp inhibitors. Sci Transl Med, 2, 53-75. Ren Y, Zhou X, Mei M, et al (2010).
-
(2010)
Sci Transl Med
, vol.2
, pp. 53-75
-
-
Wetterskog, D.1
Mendes-Pereira, A.M.2
-
27
-
-
1842852634
-
Pharmacogenomic profiling of the pi3k/pten-akt-mtor pathway in common human tumors
-
Xu G, Zhang W, Bertram P, et al (2004).Pharmacogenomic profiling of the pi3k/pten-akt-mtor pathway in common human tumors. Int J Oncol, 24, 893-900.
-
(2004)
Int J Oncol
, vol.24
, pp. 893-900
-
-
Xu, G.1
Zhang, W.2
Bertram, P.3
-
28
-
-
77956882253
-
Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance
-
Zuo Q, Shi M, Li L, et al (2010). Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance. Biomed Pharmacother, 64, 550-8
-
(2010)
Biomed Pharmacother
, vol.64
, pp. 550-558
-
-
Zuo, Q.1
Shi, M.2
Li, L.3
|