Radiolysis of paracetamol in dilute aqueous solution

Radiation Physics and Chemistry

Volumn 81, Issue 9, 2012, Pages 1503-1507

  Szabó, László ^a,b   Tóth, Tünde ^b   Homlok, Renáta ^a   Takács, Erzsébet ^a   Wojnárovits, László ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

Author keywords

Acetaminophen; Advanced oxidation processes; Hydroxyl radical; Paracetamol; Toxicity

Indexed keywords

ACETAMINOPHEN; ADVANCED OXIDATION PROCESSES; AROMATIC RINGS; DILUTE AQUEOUS SOLUTION; HIGHLY SENSITIVE; HYDROXYL RADICALS; INITIAL EFFICIENCY; LOW DOSE; PARACETAMOL;

IRRADIATION; MOLECULES; OXIDATION RESISTANCE; RADIATION CHEMISTRY; RADIOLYSIS; TOXICITY;

REACTION INTERMEDIATES;

ACETAMIDE; HYDROXY CYCLOHEXADIENYL RADICAL; HYDROXYL RADICAL; OXYGEN; PARACETAMOL; PARACETAMOL DERIVATIVE; PEROXY RADICAL; QUINONE DERIVATIVE; RADICAL; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); DECOLORATION; DILUTION; DISSOLUTION; DRUG DEGRADATION; HYDROXYLATION; IRRADIATION; MINERALIZATION; RADIOCHEMISTRY; RADIOLYSIS; TOXICITY TESTING;

EID: 84863300552     PISSN: 0969806X     EISSN: 18790895     Source Type: Journal    
DOI: 10.1016/j.radphyschem.2011.11.036     Document Type: Article

References (20)

1. 2/UV system. Water Res. 2003, 37:993-1004.
2. Bisby R.H., Tabassum N. Properties of the radicals formed by one-electron oxidation of acetaminophen-a pulse radiolysis study. Biochem. Pharmacol. 1988, 37:2731-2738.
3. Brillas E., Sirés I., Arias C., Cabot P.L., Centellas F., Rodríguez R.M., Garrido J.A. Mineralization of paracetamol in aqueous medium by anodic oxidation with boron-doped diamond electrode. Chemosphere 2005, 58:399-406.
4. 2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry GC-MS. J. Braz. Chem. Soc. 2008, 19:81-88.
5. Farré M., Ferrer I., Ginebreda A., Figueras M., Olivella L., Tirapu L., Vilanova M., Barceló D. Determination of drugs in surface water and wastewater samples by liquid chromatography-mass spectrometry: methods and preliminary results including toxicity studies with Vibrio fischeri. J. Chromatogr. 2001, 95:187-197.
6. Földváry C.S.M., Wojnárovits L. Role of reactive intermediates in the radiolytic degradation of Acid Red 1 in aqueous solution. Radiat. Phys. Chem. 2009, 78:13-18.
7. Gunatilleka A.D., People C.F. Models for estimating the non-specific toxicity of organic compounds. Anal. Chem. 1999, 36:235-242.
8. Homlok R., Takács E., Wojnárovits L. Radiolytic degradation of 2,4-dichlorophenoxyacetic acid in dilute aqueous solution: pH dependence. J. Radioanal. Nucl. Chem. 2010, 284:415-419.
9. IAEA, 2007. Radiation Processing: Environmental Applications, International Atomic Energy Agency, Vienna, 92-0-100507-5.
10. Jovanovic S.V., Hara Y., Steenken S., Simic M.G. Antioxidant potential of gallocatechins. A pulse radiolysis and laser photolysis study. J. Amer. Chem. Soc. 1995, 117:9881-9888.
11. Kim Y., Choi K., Jung J., Park S., Kim P.-G., Park J. Aquatic toxicity of acetaminophen carbamazephine, cimetidine, diltiazem and six major sulfonamides, and their potential risks in Korea. Environ. Int. 2007, 33:370-375.
12. Pálfi T., Wojnárovits L., Takács E. Calculated and measured product yields in pulse radiolysis of aqueous solutions: concentration dependence. Radiat. Phys. Chem. 2010, 79:1154-1158.
13. 2+, and UVA light on electrochemical hydrogen peroxide. J. Electrochem. Soc. 2006, 153:D1-D9.
14. Spinks J.W.T., Woods R.J. An Introduction to Radiation Chemistry 1990, Wiley-Interscience, New York. third ed.
15. 15N-aided inventory of nitrogenous breakdown products. J. Org. Chem. 2002, 67:6143-6151.
16. Von Sonntag C., Schuchmann H.-P. The chemistry behind the application of ionizing radiation in water-pollution abatement. Stud. Phys. Theor. Chem. 2001, 87:657-670.
17. Waterston K., Wang J.W.J., Bejan D., Bunce N.J. Electrochemical waste water treatment: electrooxidation of acetaminophen. J. Appl. Electrochem. 2006, 36:227-232.
18. 2 photocatalysis. Water Res. 2008, 42:3480-3488.
19. Yang L., Yu L.E., Ray M.B. Photocatalytic oxidation of paracetamol: dominant reactants, intermediates, and reaction mechanisms. Environ. Sci. Technol. 2009, 43:460-465.
20. Zona R., Solar S. Oxidation of 2,4-dichlorophenoxyacatic acid by ionizing radiation: degradation, detoxification and mineralization. Radiat. Phys. Chem. 2003, 66:137-143.