Ethnopharmacokinetic- and activity-guided isolation of a new antidepressive compound from Fructus Aurantii found in the traditional Chinese medicine Chaihu-Shugan-San: A new approach and its application

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Fan, Rong ^a,b   Huang, Xi ^a,b   Wang, Yang ^a,b   Chen, Xiao ^c   Ren, Ping ^a   Ji, Hui ^a,b   Xie, Ying ^a,b   Zhang, Yingjin ^a,b   Huang, Wei ^a,b   Qiu, Xinjian ^a,b   Liu, Zhaoqian ^b   Zhou, Honghao ^b   Fan, Lan ^b   Gao, Lichen ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c Jiangxi Qingfeng Pharmaceutical Company Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CHAIHU SHUGAN SA; CHINESE DRUG; FLUOXETINE; MERAZIN HYDRATE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CASE REPORT; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; ETHNOPHARMACOKINETIC AND ACTIVITY GUIDED ISOLATION; HUMAN; IMMOBILIZATION; LOCOMOTION; MAJOR DEPRESSION; MALE; PRIORITY JOURNAL; SOUR ORANGE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84863290802     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/607584     Document Type: Article

References (31)

1. Meunier B., Hybrid molecules with a dual mode of action: dream or reality? Accounts of Chemical Research 2008 41 1 69 77
2. Queiroz E. F., Wolfender J. L., Hostettmann K., Modern approaches in the search for new lead antiparasitic compounds from higher plants Current Drug Targets 2009 10 3 202 211
3. Alavijeh M. S., Palmer A. M., The pivotal role of drug metabolism and pharmacokinetics in the discovery and development of new medicines IDrugs 2004 7 8 755 763
4. Pavel D., Jitka M., Recent advances in analysis of Chinese medical plants and traditional medicines Journal of Chromatography B 2004 812 1-2 3 21
5. Homma M., Oka K., Yamada T., Niitsuma T., Ihto H., Takahashi N., A strategy for discovering biologically active compounds with high probability in traditional Chinese herb remedies: an application of Saiboku- to in bronchial asthma Analytical Biochemistry 1992 202 1 179 187
6. Kim S. H., Han J., Seog D. H., Chung J. Y., Kim N., Hong Park Y., Lee S. K., Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depression Life Sciences 2005 76 11 1297 1306 (Pubitemid 40092143)
7. Fossati P., Coyette F., Ergis A. M., Allilaire J. F., Influence of age and executive functioning on verbal memory of inpatients with depression Journal of Affective Disorders 2002 68 2-3 261 271 (Pubitemid 34628333)
8. Zheng L., Lin Z., Zhu Z., Observation of the therapeutic effect of modified Chaihu Shugan powder combined with deanxit on functional dyspepsia Chinese Journal of Integrated Traditional and Western Medicine on Digestion 2005 13 38 40
9. Dong H., Liu Z., Song F., Yu Z., Li H., Liu S., Structural analysis of monoterpene glycosides extracted from Paeonia lactiflora Pall. using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry and high-performance liquid chromatography/ electrospray ionization tandem mass spectrometry Rapid Communications in Mass Spectrometry 2007 21 19 3193 3199 (Pubitemid 47441780)
10. Huang X., Qin F., Zhang H. M., Xiao H. B., Wang L. X., Zhang X. Y., Ren P., Cardioprotection by Guanxin II in rats with acute myocardial infarction is related to its three compounds Journal of Ethnopharmacology 2009 121 2 268 273
11. Wang Y., Yao Y., An R., You L., Wang X., Simultaneous determination of puerarin, daidzein, baicalin, wogonoside and liquiritin of GegenQinlian decoction in rat plasma by ultra-performance liquid chromatography-mass spectrometry Journal of Chromatography B 2009 877 20-21 1820 1826
12. Wang Y., Yang L., He Y. Q., Wang C. H., Welbeck E. W., Bligh S. W. A., Wang Z. T., Characterization of fifty-one flavonoids in a Chinese herbal prescription Longdan Xiegan Decoction by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry and photodiode array detection Rapid Communications in Mass Spectrometry 2008 22 12 1767 1778 (Pubitemid 351947741)
13. Yu Q., Xiang J., Tang W., Liang M., Qin Y., Nan F., Simultaneous determination of the 10 major components of Da-Cheng-Qi decoction in dog plasma by liquid chromatography tandem mass spectrometry Journal of Chromatography B 2009 877 22 2025 2031
14. Zhou D. Y., Xu Q., Xue X. Y., Zhang F. F., Liang X. M., Identification of O-diglycosyl flavanones in Fructus aurantii by liquid chromatography with electrospray ionization and collision-induced dissociation mass spectrometry Journal of Pharmaceutical and Biomedical Analysis 2006 42 4 441 448 (Pubitemid 44375110)
15. Tam C. U., Yang F. Q., Zhang Q. W., Guan J., Li S. P., Optimization and comparison of three methods for extraction of volatile compounds from Cyperus rotundus evaluated by gas chromatography-mass spectrometry Journal of Pharmaceutical and Biomedical Analysis 2007 44 2 444 449 (Pubitemid 46880076)
16. Zou Q., Wei P., Li J., Ge Z. X., Ouyang P., Simultaneous determination of 18 -and 18 -glycyrrhetic acid in human plasma by LC-ESI-MS and its application to pharmacokinetics Biomedical Chromatography 2009 23 1 54 62
17. Zhang Y. Q., Ling J. H., Liang G., Effects of Chaihushugansan on GASR mRNA and CCK-AR mRNA expression in stress rats Lishizhen Medicine and Materia Medica Research 2010 21 1081 1083
18. Huang W., Huang X., Xing Z., Qiu X., Wang Y., Fan R., Liu W., Ren P., Liu Z., Zhou H., Meranzin hydrate induces similar effect to Fructus Aurantii on intestinal motility through activation of H1 histamine receptors Journal of Gastrointestinal Surgery 2011 15 1 87 96
19. dos Santos A. A., Pinheiro P. C. F., de Lima D. S. C., Ozias M. G., de Oliveira M. B., Guimares N. X., Guedes R. C. A., Fluoxetine inhibits cortical spreading depression in weaned and adult rats suckled under favorable and unfavorable lactation conditions Experimental Neurology 2006 200 2 275 282 (Pubitemid 44107910)
20. Broom D. C., Jutkiewicz E. M., Folk J. E., Traynor J. R., Rice K. C., Woods J. H., Nonpeptidic -opioid receptor agonists reduce immobility in the forced swim assay in rats Neuropsychopharmacology 2002 26 6 744 755 (Pubitemid 34455027)
21. Régine D., Paul B., Suzanne F. F., A new bicoumarin from the leaves and stems of Triphasia trifolia Fitoterapia 2006 77 2 129 133
22. Hu S. H., Huang X., Liang Q. H., Simultaneously qualitative determination of multiple compounds in Chaihu Shugan san and in rat intestine by UPLC-PDA Journal of Medical Research 2010 39 7 42 45
23. Qiu X. J., Huang X., Chen Z. Q., Pharmacokinetic study of the prokinetic compounds meranzin hydrate and ferulic acid following oral administration of Chaihu-Shugan-San to patients with functional dyspepsia Journal of Ethnopharmacology 2011 137 1 205 213
24. Schadt E. E., Zhang B., Zhu J., Advances in systems biology are enhancing our understanding of disease and moving us closer to novel disease treatments Genetica 2009 136 2 259 269
25. Riviere C., Goossens L., Pommery N., Fourneau C., Delelis A., Henichart J. P., Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker Natural Product Research 2006 20 10 909 916 (Pubitemid 44144701)
26. Rosselli S., Maggio A., Bellone G., Formisano C., Basile A., Cicala C., Alfieri A., Mascolo N., Bruno M., Antibacterial and anticoagulant activities of coumarins isolated from the flowers of Magydaris tomentosa Planta Medica 2007 73 2 116 120 (Pubitemid 46910428)
27. Teng W. Y., Chen C. C., Chung R. S., HPLC comparison of supercritical fluid extraction and solvent extraction of coumarins from the peel of Citrus maxima fruit Phytochemical Analysis 2005 16 6 459 462
28. Saied S., Nizami S. S., Anis I., Two new coumarins from Murraya paniculata Journal of Asian Natural Products Research 2008 10 6 515 519 (Pubitemid 351883083)
29. Zhou D. Y., Chen D. L., Xu Q., Xue X. Y., Zhang F. F., Liang X. M., Characterization of polymethoxylated flavones in Fructus aurantii by liquid chromatography with atmospheric pressure chemical ionization combined with tandem mass spectrometry Journal of Pharmaceutical and Biomedical Analysis 2007 43 5 1692 1699 (Pubitemid 46453079)
30. Wang C., Pan Y., Fan G., Chai Y., Wu Y., Application of an efficient strategy based on MAE, HPLC-DAD-MS/MS and HSCCC for the rapid extraction, identification, separation and purification of flavonoids from Fructus Aurantii Immaturus Biomedical Chromatography 2010 24 3 235 244
31. Balani S. K., Miwa G. T., Gan L. S., Wu J. T., Lee F. W., Strategy of utilizing in vitro and in vivo ADME tools for lead optimizaton and drug candidate selection Current Topics in Medicinal Chemistry 2005 5 11 1033 1038 (Pubitemid 41582117)