Persistence of Orientia tsutsugamushi in humans

Journal of Korean Medical Science

Volumn 27, Issue 3, 2012, Pages 231-235

  Chung, Moon Hyun ^a   Lee, Jin Soo ^a   Baek, Ji hyeon ^a   Kim, Mijeong ^a   Kang, Jae Seung ^a  

^a Inha University School of Medicine   (South Korea)

Author keywords

Atherosclerosis; Orientia tsutsugamushi; Persistence; Recurrence; Scrub typhus

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL DNA; BACTERIAL PROTEIN; MEMBRANE PROTEIN; STA56 ANTIGEN, RICKETTSIA TSUTSUGAMUSHI;

ADULT; AGED; ARTICLE; BACTERIAL GENE; CASE CONTROL STUDY; CASE REPORT; CHRONIC DISEASE; CORONARY ARTERY DISEASE; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; MIDDLE AGED; MUSCLE WEAKNESS; NUCLEOTIDE SEQUENCE; ORIENTIA TSUTSUGAMUSHI; RECURRENT DISEASE; SCRUB TYPHUS; TIME; TRANSIENT ISCHEMIC ATTACK;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BASE SEQUENCE; CASE-CONTROL STUDIES; CHRONIC DISEASE; CORONARY ARTERY DISEASE; DNA, BACTERIAL; FEMALE; GENES, BACTERIAL; HUMANS; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUSCLE WEAKNESS; ORIENTIA TSUTSUGAMUSHI; RECURRENCE; SCRUB TYPHUS; TIME FACTORS;

EID: 84863267268     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2012.27.3.231     Document Type: Article

References (23)

1. Murai K, Okayama A, Horinouchi H, Oshikawa T, Tachibana N, Tsubouchi H. Eradication of Rickettsia tsutsugamushi from patients' blood by chemotherapy, as assessed by the polymerase chain reaction. Am J Trop Med Hyg 1995; 52: 325-7.
2. Saisongkorh W, Chenchittikul M, Silpapojakul K. Evaluation of nested PCR for the diagnosis of scrub typhus among patients with acute pyrexia of unknown origin. Trans R Soc Trop Med Hyg 2004; 98: 360-6.
3. Kim DM, Yun NR, Yang TY, Lee JH, Yang JT, Shim SK, Choi EN, Park MY, Lee SH. Usefulness of nested PCR for the diagnosis of scrub typhus in clinical practice: a prospective study. Am J Trop Med Hyg 2006; 75: 542-5.
4. Kim DM, Byun JN. Effects of antibiotic treatment on the results of nested PCRs for scrub typhus. J Clin Microbiol 2008; 46: 3465-6.
5. Hayashi H, Watanabe M. On the possibility of appearance of rickettsiae in the circulating blood after the recovery of rickettsiosis. Kitasato Arch Exp Med 1948; 21: 135-41.
6. Rights FL, Smadel JE. Studies on scrub typhus; tsutsugamushi disease: heterogenicity of strains of R. tsutsugamushi as demonstrated by crossvaccination studies. J Exp Med 1948; 87: 339-51.
7. Smadel JE, Ley HL Jr, Diercks FH, Cameron JA. Persistence of Rickettsia tsutsugamushi in tissues of patients recovered from scrub typhus. Am J Hyg 1952; 56: 294-302.
8. Jackson EB, Danauskas JX, Smadel JE, Fuller HS, Coale MC, Bozeman FM. Occurrence of Rickettsia tsutsugamushi in Korean rodents and chiggers. Am J Hyg 1957; 66: 309-20.
9. Song HJ, Seong SY, Huh MS, Park SG, Jang WJ, Kee SH, Kim KH, Kim SC, Choi MS, Kim IS, Chang WH. Molecular and serologic survey of Orientia tsutsugamushi infection among field rodents in southern Cholla Province, Korea. Am J Trop Med Hyg 1998; 58: 513-8.
10. Smadel JE, Jackson EB, Cruise AB. Chloromycetin in experimental rickettsial infections. J Immunol 1949; 62: 49-65.
11. Takahashi M, Murata M, Sasaki M, Saito T, Machida K, Hori E, Tanaka H, Kawamura A Jr. Resistance to Rickettsia tsutsugamushi and persistence of infection in different wild rodents. Jpn J Exp Med 1990; 60: 241-5.
12. Fox JP. The long persistence of Rickettsia orientalis in the blood and tissues of infected animals. J Immunol 1948; 59: 109-14.
13. Kee SH, Choi IH, Choi MS, Kim IS, Chang WH. Detection of Rickettsia tsutsugamushi in experimentally infected mice by PCR. J Clin Microbiol 1994; 32: 1435-9.
14. Shirai A, Chan TC, Gan E, Huxsoll DL. Persistence and reactivation of Rickettsia tsutsugamushi infections in laboratory mice. Jpn J Med Sci Biol 1979; 32: 179-84.
15. Kim MK, Kee SH, Cho KA, Chung MH, Lim BU, Chang WH, Kang JS. Apoptosis of endothelial cell line ECV304 persistently infected with Orientia tsutsugamushi. Microbiol Immunol 1999; 43: 751-7.
16. Smadel JE, Jackson EB, Ley HL Jr. Terramycin as a rickettsiostatic agent and its usefulness in patients with scrub typhus. Ann N Y Acad Sci 1950; 53: 375-84.
17. Smadel JE, Ley HL Jr, Diercks FH, Traub R. Immunity in scrub typhus: resistance to induced reinfection. AMA Arch Pathol 1950; 50: 847-61.
18. Brown J, Reading SJ, Jones S, Fitchett CJ, Howl J, Martin A, Longland CL, Michelangeli F, Dubrova YE, Brown CA. Critical evaluation of ECV304 as a human endothelial cell model defined by genetic analysis and functional responses: a comparison with the human bladder cancer derived epithelial cell line T24/83. Lab Invest 2000; 80: 37-45.
19. Qiang Y, Tamura A, Urakami H, Makisaka Y, Koyama S, Fukuhara M, Kadosaka T. Phylogenetic characterization of Orientia tsutsugamushi isolated in Taiwan according to the sequence homologies of 56-kDa typespecific antigen genes. Microbiol Immunol 2003; 47: 577-83.
20. Shirai A, Saunders JP, Dohany AL, Huxsoll DL, Groves MG. Transmission of scrub typhus to human volunteers by laboratory-reared chiggers. Jpn J Med Sci Biol 1982; 35: 9-16.
21. Kramme S, An le V, Khoa ND, Trin le V, Tannich E, Rybniker J, Fleischer B, Drosten C, Panning M. Orientia tsutsugamushi bacteremia and cytokine levels in Vietnamese scrub typhus patients. J Clin Microbiol 2009; 47: 586-9.
22. Watt G, Jongsakul K, Suttinont C. Possible scrub typhus coinfections in Thai agricultural workers hospitalized with leptospirosis. Am J Trop Med Hyg 2003; 68: 89-91.
23. Danesh J, Appleby P. Persistent infection and vascular disease: a systematic review. Expert Opin Investig Drugs 1998; 7: 691-713.