Mechanisms involved in biological behavior changes associated with Angptl4 expression in colon cancer cell lines

Oncology Reports

Volumn 27, Issue 5, 2012, Pages 1541-1547

  Huang, Xue Feng ^a   Han, Jie ^a   Hu, Xiao Tong ^a   He, Chao ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b Key Laboratory of Biotherapy of Zhejiang Province   (China)

Author keywords

Angptl4; Colorectal cancer; Cytoskeleton; Metastasis

Indexed keywords

EZRIN; F ACTIN; MESSENGER RNA; MOESIN; RADIXIN; UVOMORULIN;

ANGPTL4 GENE; ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CELLULAR DISTRIBUTION; COLON CANCER; CONTROLLED STUDY; CORRELATIONAL STUDY; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOPODIUM; QUANTITATIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; TISSUE DISTRIBUTION;

ACTINS; ADULT; AGED; AGED, 80 AND OVER; ANGIOPOIETINS; ANIMALS; ANTIGENS, CD44; CADHERINS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLONIC NEOPLASMS; CYTOSKELETAL PROTEINS; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMANS; INTESTINAL MUCOSA; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROFILAMENT PROTEINS; MIDDLE AGED; PHOSPHOPROTEINS; PSEUDOPODIA; TRANSPLANTATION, HETEROLOGOUS;

EID: 84863265580     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1672     Document Type: Article

References (20)

1. Jemal A, Siegel R, Xu J and Ward E: Cancer Statistics, 2010. CA Cancer J Clin 60: 277-300, 2010.
2. Markowitz SD and Bertagnolli MM: Molecular origins of cancer: molecular basis of colorectal cancer. N Engl J Med 361: 2449-2460, 2009.
3. Yau MH, Wang Y, Lam KS, Zhang J, Wu D, et al: A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization. J Biol Chem 284: 11942-11952, 2009.
4. Ito Y, Oike Y, Yasunaga K, Hamada K, Miyata K, et al: Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4. Cancer Res 1563: 6651-6657, 2003. (Pubitemid 37322943)
5. Zhu H, Li J, Qin W, Yang Y, He X, et al: Cloning of a novel gene, ANGPTL4 and the functional study in angiogenesis. Zhonghua Yi Xue Za Zhi 82: 94-99, 2002.
6. Xu A, Lam MC, Chan KW, Wang Y, Zhang J, et al: Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci USA 102: 6086-6091, 2005. (Pubitemid 40594259)
7. Li KQ, Li WL, Peng SY, Shi XY, Tang HL, et al: Anti-tumor effect of recombinant retroviral vector-mediated human ANGPTL4 gene transfection. Chin Med J (Engl) 117: 1364-1369, 2004.
8. Galaup A, Cazes A, Le Jan S, Philippe J, Connault E, et al: Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness. Proc Natl Acad Sci USA 103: 18721-18726, 2006. (Pubitemid 44913477)
9. Kaneda A, Kaminishi M, Yanagihara K, Sugimura T and Ushijima T: Identification of silencing of nine genes in human gastric cancers. Cancer Res 62: 6645-6650, 2002. (Pubitemid 35364133)
10. LeJan S, Amy C, Cazes A, Monnot C, Lamande N, et al: Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma. Am J Pathol 162: 1521-1528, 2003. (Pubitemid 36512834)
11. Nakayama T, Hirakawa H, Shibata K, Abe K, Nagayasu T, et al: Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion. Oncol Rep 24: 599-606, 2010.
12. Wang Z, Han B, Zhang Z, Pan J and Xia H: Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma. Biomarkers 15: 39-46, 2010.
13. Shibata K, Nakayama T, Hirakawa H, Hidaka S and Nagayasu T: Clinicopathological significance of angiopoietin-like protein 4 expression in oesophageal squamous cell carcinoma. J Clin Pathol 63: 1054-1058, 2010.
14. Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, et al: TGF beta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 133: 66-77, 2008. (Pubitemid 351442989)
15. Beavon IR: The E-cadherin-catenin complex in tumor metastasis: structure, function and regulation. Eur J Cancer 36: 1607-1620, 2000.
16. Cavallaro U and Christofori G: Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough. Biochim Biophys Acta 1552: 39-45, 2001. (Pubitemid 34066627)
17. Barbour AP, Reeder JA, Walsh MD, et al: Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3. Cancer Res 63: 887-892, 2003. (Pubitemid 36231993)
18. Weber GF, Bronson RT, Ilagan J, et al: Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res 62: 2281-2286, 2002. (Pubitemid 34411705)
19. Yu Q, Toole BP and Stamenkovic I: Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function. J Exp Med 186: 1985-1996, 1997. (Pubitemid 28013682)
20. Wong K, Rubenthiran U and Jothy S: Motility of colon cancer cells: modulation by CD44 isoform expression. Exp Mol Pathol 75: 124-130, 2003. (Pubitemid 37152502)