M 3 subtype of muscarinic acetylcholine receptor promotes cardioprotection via the suppression of mir-376b-5p

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Pan, Zhenyu ^a   Guo, Yueping ^a   Qi, Hanping ^a   Fan, Kai ^a   Wang, Shu ^a   Zhao, Hua ^a   Fan, Yuhua ^a   Xie, Jing ^a   Guo, Feng ^a   Hou, Yunlong ^a   Wang, Ning ^a   Huo, Rong ^a   Zhang, Yong ^a   Liu, Yan ^a   Du, Zhimin ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM ION; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 376B 5P; MUSCARINIC M3 RECEPTOR; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CALCIUM; CHOLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; MICROARRAY ANALYSIS; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOLOGICAL MODEL; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HEART INFARCTION; HEART MUSCLE CELL; ISCHEMIA; METABOLISM; PATHOLOGY; WISTAR RAT;

RATTUS;

ANIMALS; CALCIUM; CELL LINE; CHOLINE; DOWN-REGULATION; GENE EXPRESSION REGULATION; ISCHEMIA; MALE; MICRORNAS; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; NF-KAPPA B; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTOR, MUSCARINIC M3;

EID: 84863264024     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032571     Document Type: Article

References (45)

1. Ferdinandy P, Schulz R, Baxter GF, (2007) Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning. Pharmacol Rev 59: 418-458.
2. Bolli R, Fisher DJ, Taylor AA, Young JB, Miller RR, (1984) Effect of alpha-adrenergic blockade on arrhythmias induced by acute myocardial ischemia and reperfusion in the dog. J Mol Cell Cardiol 16: 1101-1117.
3. Myerburg RJ, Kessler KM, Castellanos A, (1993) Sudden cardiac death: epidemiology, transient risk, and intervention assessment. Ann Intern Med 119: 1187-1197.
4. Ferreira M, Santos-Silva PR, de Abreu LC, Valenti VE, Crispim V, et al. (2010) Sudden cardiac death athletes: a systematic review. Sports Med Arthrosc Rehabil Ther Technol 2: 19.
5. Downey JM, Cohen MV, (2009) Why do we still not have cardioprotective drugs? Circulation 73: 1171-1177.
6. Shi H, Wang H, Wang Z, (1999) Identification and characterization of multiple subtypes of muscarinic acetylcholine receptors and their physiological functions in canine hearts. Mol Pharmacol 55: 497-507.
7. Yang B, Lin H, Xu C, Liu Y, Wang H, et al. (2005) Choline produces cytoprotective effects against ischemic myocardial injuries: evidence for the role of cardiac M3 subtype muscarinic acetylcholine receptors. Cell Physiol Biochem 16: 163-174.
8. Yue P, Zhang Y, Du Z, Xiao J, Pan Z, et al. (2006) Ischemia impairs the association between connexin 43 and M3 subtype of acetylcholine muscarinic receptor (M3-mAChR) in ventricular myocytes. Cell Physiol Biochem 17: 129-136.
9. Liu Y, Sun HL, Li DL, Wang LY, Gao Y, et al. (2008) Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism. Can J Physiol Pharmacol 86: 860-865.
10. Liu Y, Du J, Gao Y, Zhang Y, Cai BZ, et al. (2009) Role of M3 receptor in aconitine/barium-chloride-induced preconditioning against arrhythmias in rats. Naunyn Schmiedebergs Arch Pharmacol 379: 511-515.
11. Yang B, Lin H, Xiao J, Lu Y, Luo X, et al. (2007) The muscle-specific microRNAmiR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med 13: 486-491.
12. Li Q, Song XW, Zou J, Wang GK, Kremneva E, et al. (2010) Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy. J Cell Sci 123: 2444-2452.
13. Kumarswamy R, Anker SD, Thum T, (2010) MicroRNAs as circulating biomarkers for heart failure: questions about MiR-423-5p. Circ Res 106: e8.
14. Matkovich SJ, Wang W, Tu Y, Eschenbacher WH, Dorn LE, et al. (2010) MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res 106: 166-175.
15. Ren XP, Wu J, Wang X, Sartor MA, Qian J, et al. (2009) MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20. Circulation 119: 2357-2366.
16. Cheng Y, Zhu P, Yang J, Liu X, Dong S, et al. (2010) Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4. Cardiovasc Res 87: 431-439.
17. Wang X, Zhang X, Ren XP, Chen J, Liu H, et al. (2010) MicroRNA-494 Targeting Both Proapoptotic and Antiapoptotic Proteins Protects Against Ischemia/Reperfusion-Induced Cardiac Injury. Circulation 122: 1308-1318.
18. Fujino H, Uehara T, Murayama T, Okuma Y, Ariga H, et al. (2000) Extracellular signal regulated protein kinase and c-jun N-terminal kinase are involved in ml muscarinic receptor-enhanced interleukin-2 production pathway in Jurkat cells. J Biol Pharm Bull 23: 1198-1205.
19. Siehler S, Wang Y, Fan X, Windh RT, Manning DR, (2001) Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells. J Biol Chem 276: 48733-48739.
20. Zheng H, Chen D, Zhang J, Tian Y, (2004) Involvement of M3 cholinergic receptor signal transduction pathway in regulation of the expression of chemokine MOB-1, MCP-1 genes in pancreatic acinar cells. J Huazhong Univ Sci Technolog Med Sci 24: 140-143, 157.
21. Valen G, Yan ZQ, Hansson GK, (2001) Nuclear factor kappa-B and the heart. J Am Coll Cardiol 38: 307-314.
22. Taganov KD, Boldin MP, Chang KJ, Baltimore D, (2006) NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 103: 12481-12486.
23. Bazzoni F, Rossato M, Fabbri M, Gaudiosi D, Mirolo M, et al. (2009) Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc Natl Acad Sci USA 106: 5282-5287.
24. Akanji AO, Suresh CG, Al-Radwan R, Fatania HR, (2007) Insulin-like growth factor (IGF)-I, IGF-II and IGF-binding protein (IGFBP)-3 levels in Arab subjects with coronary heart disease. Scand J Clin Lab Invest 67: 553-559.
25. Chu CH, Tzang BS, Chen LM, Kuo CH, Cheng YC, et al. (2008) IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells. J Endocrinol 197: 381-390.
26. Guo ZY, Jiao Q, Wang ST, Xu MH, Gao FH, (2008) Effect of ryanodine receptor 2 gene silencing on ischemia-reperfusion injury of rat myocardial cells. Zhonghua Bing Li Xue Za Zhi 37: 760-764.
27. Guo Z, Wang S, Jiao Q, Xu M, Gao F, (2010) RNAi targeting ryanodine receptor 2 protects rat cardiomyocytes from injury caused by simulated ischemia-reperfusion. Biomed Pharmacother 64: 184-190.
28. Fauconnier J, Pasquié JL, Bideaux P, Lacampagne A, Richard S, (2010) Cardiomyocytes hypertrophic status after myocardial infarction determines distinct types of arrhythmia: role of the ryanodine receptor. Prog Biophys Mol Biol 103: 71-80.
29. Luo Z, Diaco M, Murohara T, Ferrara N, Isner JM, et al. (1997) Vascular endothelial growth factor attenuates myocardial ischemia-reperfusion injury. The Annals of thoracic surgery 64: 993-998.
30. Donovan MJ, Lin MI, Wiegn P, Ringstedt T, Kraemer R, et al. (2000) Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development 127: 4531-4540.
31. Hiltunen JO, Laurikainen A, Väkevä A, Meri S, Saarma M, (2001) Nerve growth factor and brain-derived neurotrophic factor mRNAs are regulated in distinct cell populations of rat heart after ischaemia and reperfusion. J Pathol 194: 247-253.
32. Nakamura K, Martin KC, Jackson JK, Beppu K, Woo CW, et al. (2006) Brain-derived neurotrophic factor activation of TrkB induces vascular endothelial growth factor expression via hypoxia-inducible factor-1alpha in neuroblastoma cells. Cancer research 66: 4249-4255.
33. Kreusser MM, Buss SJ, Krebs J, Kinscherf R, Metz J, et al. (2008) Differential expression of cardiac neurotrophic factors and sympathetic nerve ending abnormalities within the failing heart. J Mol Cell Cardiol 44: 380-387.
34. Lorgis L, Amoureux S, Vergely C, Zeller M, Cottin Y, et al. (2009) Brain-derived neurotrophic factor (BDNF): role of this neurotrophin in cardiovascular physiopathology. Ann Cardiol Angeiol 58: 99-103.
35. Katare RG, Kakinuma Y, Arikawa M, Yamasaki F, Sato T, (2009) Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway. J Mol Cell Cardiol 46: 405-412.
36. Maulik N, Sato M, Price BD, Das DK, (1998) An essential role of NFkappaB in tyrosine kinase signaling of p38 MAP kinase regulation of myocardial adaptation to ischaemia. FEBS Lett 429: 365-369.
37. Maulik N, Goswami S, Galang N, Das DK, (1999) Differential regulation of Bcl-2, AP-1, and NFkappaB on cardiomyocyte apoptosis during myocar-dial ischemic stress adaption. FEBS Lett 443: 331-336.
38. Dana A, Jonassen AK, Yamashita N, Yellon DM, (2000) Adenosine A(1) receptor activation induces delayed preconditioning in rats mediated by manganese superoxide dismutase. Circulation 101: 2841-2848.
39. Gumina RJ, Newman PJ, Kenny D, Warltier DC, Gross GJ, (1997) The eukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury. Basic Res Cardiol 92: 201-213.
40. Shimizu N, Yoshiyama M, Omura T, Hanatani A, Kim S, et al. (1998) Activation of mitogen-activated protein kinases and activator protein-1 in myocardial infarction in rats. Cardiovasc Res 38: 116-124.
41. Cain BS, Harken AH, Meldrum DR, (1999) Therapeutic strategies to reduce TNF-alpha mediated cardiac contractile depression following ischemia and reperfusion. J Mol Cell Cardiol 31: 931-947.
42. Ono K, Matsumori A, Furukawa Y, Igata H, Shioi T, et al. (1999) Prevention of myocardial reperfusion injury in rats by an antibody against monocyte chemotactic and activating factor/monocyte chemoattractant protein-1. Lab Invest 79: 195-203.
43. Morgan EN, Boyle EM, Yun W, Griscavage-Ennis JM, Farr AL, et al. (1999) An essential role for NFkappaB in the cardioadaptive response to ischemia. Ann Thorac Surg 68: 377-382.
44. Xuan YT, Tang XL, Banerjee S, Takano H, Li RC, et al. (1999) Nuclear factor-kB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits. Circ Res 84: 1095-1109.
45. Todisco A, Ramamoorthy S, Pausawasdi N, Tacey K, (1999) Carbachol activates IkappaB kinase in isolated canine gastric parietal cells. J Biochem Biophys Res Commun 261: 877-884.