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Volumn 7, Issue 3, 2012, Pages

Cholesteryl ester transfer protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN; MESSENGER RNA; ATENOLOL; CETP PROTEIN, HUMAN; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ISOPROTEIN; VERAPAMIL;

EID: 84863259244     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031930     Document Type: Article
Times cited : (62)

References (38)
  • 1
    • 1842815777 scopus 로고    scopus 로고
    • Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol
    • Brousseau M, Schaefer E, Wolfe M, Bloedon L, Digenio A, et al. (2004) Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. N Engl J Med 350: 1505-1515.
    • (2004) N Engl J Med , vol.350 , pp. 1505-1515
    • Brousseau, M.1    Schaefer, E.2    Wolfe, M.3    Bloedon, L.4    Digenio, A.5
  • 3
    • 36348975228 scopus 로고    scopus 로고
    • ILLUMINATE Investigators. Effects of torcetrapib in patients at high risk for coronary events
    • Barter P, Caulfield M, Eriksson M, Grundy S, Kastelein J, et al. (2007) ILLUMINATE Investigators. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med 357: 2109-2122.
    • (2007) N Engl J Med , vol.357 , pp. 2109-2122
    • Barter, P.1    Caulfield, M.2    Eriksson, M.3    Grundy, S.4    Kastelein, J.5
  • 4
    • 0029948968 scopus 로고    scopus 로고
    • Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels
    • Zhong S, Sharp D, Grove J, Bruce C, Yano K, et al. (1996) Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels. J Clin Invest 97: 2917-2923.
    • (1996) J Clin Invest , vol.97 , pp. 2917-2923
    • Zhong, S.1    Sharp, D.2    Grove, J.3    Bruce, C.4    Yano, K.5
  • 5
    • 73349122606 scopus 로고    scopus 로고
    • Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community
    • Vasan RS, Pencina MJ, Robins SJ, Zachariah JP, Kaur G, et al. (2009) Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community. Circulation 120: 2414-2420.
    • (2009) Circulation , vol.120 , pp. 2414-2420
    • Vasan, R.S.1    Pencina, M.J.2    Robins, S.J.3    Zachariah, J.P.4    Kaur, G.5
  • 6
    • 17144458007 scopus 로고    scopus 로고
    • Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy Spanish population
    • Corella D, Saiz C, Guillen M, Portoles O, Mulet F, et al. (2000) Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy Spanish population. Atherosclerosis 152: 367-376.
    • (2000) Atherosclerosis , vol.152 , pp. 367-376
    • Corella, D.1    Saiz, C.2    Guillen, M.3    Portoles, O.4    Mulet, F.5
  • 7
    • 0034061148 scopus 로고    scopus 로고
    • Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk
    • Ordovas J, Cupples L, Corella D, Otvos J, Osgood D, et al. (2000) Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk. Arterioscler Thromb Vasc Biol 20: 1323-1329.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1323-1329
    • Ordovas, J.1    Cupples, L.2    Corella, D.3    Otvos, J.4    Osgood, D.5
  • 8
    • 0033945005 scopus 로고    scopus 로고
    • Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction
    • Corbex M, Poirier O, Fumeron F, Betoulle D, Evans A, et al. (2000) Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction. Genet Epidem 19: 64-80.
    • (2000) Genet Epidem , vol.19 , pp. 64-80
    • Corbex, M.1    Poirier, O.2    Fumeron, F.3    Betoulle, D.4    Evans, A.5
  • 9
    • 0038654373 scopus 로고    scopus 로고
    • Single nucleotide polymorphism haplotypes in the cholesteryl-ester transfer protein (CETP) gene and lipid phenotypes
    • Bauerfeind A, Knoblauch H, Schuster H, Luft FC, Reich JG, (2002) Single nucleotide polymorphism haplotypes in the cholesteryl-ester transfer protein (CETP) gene and lipid phenotypes. Hum Hered 54: 166-173.
    • (2002) Hum Hered , vol.54 , pp. 166-173
    • Bauerfeind, A.1    Knoblauch, H.2    Schuster, H.3    Luft, F.C.4    Reich, J.G.5
  • 10
    • 0041346384 scopus 로고    scopus 로고
    • A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders
    • Anguelova M, Benkelfat C, Turecki G, (2003) A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders. Mol Psychiatry 8: 574-591.
    • (2003) Mol Psychiatry , vol.8 , pp. 574-591
    • Anguelova, M.1    Benkelfat, C.2    Turecki, G.3
  • 11
    • 0038245111 scopus 로고    scopus 로고
    • Haplotype analyses of cholesteryl ester transfer protein gene promoter: a clue to an unsolved mystery of TaqIB polymorphism
    • Lu H, Inazu A, Moriyama Y, Higashikata T, Kawashiri M, et al. (2003) Haplotype analyses of cholesteryl ester transfer protein gene promoter: a clue to an unsolved mystery of TaqIB polymorphism. J Mol Med 81: 246-255.
    • (2003) J Mol Med , vol.81 , pp. 246-255
    • Lu, H.1    Inazu, A.2    Moriyama, Y.3    Higashikata, T.4    Kawashiri, M.5
  • 12
    • 19944431793 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects
    • Boekholdt S, Sacks F, Jukema JW, Shepherd J, Freeman D, et al. (2005) Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. Circulation 111: 278-287.
    • (2005) Circulation , vol.111 , pp. 278-287
    • Boekholdt, S.1    Sacks, F.2    Jukema, J.W.3    Shepherd, J.4    Freeman, D.5
  • 13
    • 0032495541 scopus 로고    scopus 로고
    • The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
    • Kuivenhoven JA, Jukema JW, Zwinderman AH, de Knijff P, McPherson R, et al. (1998) The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. N Engl Med 338: 86-93.
    • (1998) N Engl Med , vol.338 , pp. 86-93
    • Kuivenhoven, J.A.1    Jukema, J.W.2    Zwinderman, A.H.3    de Knijff, P.4    McPherson, R.5
  • 14
    • 0012605419 scopus 로고    scopus 로고
    • The cholesteryl ester transfer protein Taq1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease
    • Carlquist J, Muhlestein J, Horne B, Hart N, Bair T, et al. (2003) The cholesteryl ester transfer protein Taq1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease. Am Heart J 146: 929-931.
    • (2003) Am Heart J , vol.146 , pp. 929-931
    • Carlquist, J.1    Muhlestein, J.2    Horne, B.3    Hart, N.4    Bair, T.5
  • 15
    • 56449118071 scopus 로고    scopus 로고
    • CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction
    • Regieli JJ, Jukema JW, Grobbee DE, Kastelein JJ, Kuivenhoven JA, et al. (2008) CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction. Eur Heart J 29: 2792-2799.
    • (2008) Eur Heart J , vol.29 , pp. 2792-2799
    • Regieli, J.J.1    Jukema, J.W.2    Grobbee, D.E.3    Kastelein, J.J.4    Kuivenhoven, J.A.5
  • 16
    • 1242314787 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS)
    • Klerkx A, de Grooth G, Zwinderman A, Jukema J, Kuivenhoven J, et al. (2004) Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS). Eur J Clin Invest 34: 21-28.
    • (2004) Eur J Clin Invest , vol.34 , pp. 21-28
    • Klerkx, A.1    de Grooth, G.2    Zwinderman, A.3    Jukema, J.4    Kuivenhoven, J.5
  • 17
    • 10744219782 scopus 로고    scopus 로고
    • The cholesteryl ester transfer protein (CETP) TaqIB polymorphism in the cholesterol and recurrent events study: no interaction with the response to pravastatin therapy and no effects on cardiovascular outcome: a prospective analysis of the CETP TaqIB polymorphism on cardiovascular outcome and interaction with cholesterol-lowering therapy
    • de Grooth G, Zerba K, Huang S, Tsuchihashi Z, Kirchgessner T, et al. (2004) The cholesteryl ester transfer protein (CETP) TaqIB polymorphism in the cholesterol and recurrent events study: no interaction with the response to pravastatin therapy and no effects on cardiovascular outcome: a prospective analysis of the CETP TaqIB polymorphism on cardiovascular outcome and interaction with cholesterol-lowering therapy. J Am Coll Cardiol 43: 854-857.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 854-857
    • de Grooth, G.1    Zerba, K.2    Huang, S.3    Tsuchihashi, Z.4    Kirchgessner, T.5
  • 18
    • 19944431793 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects
    • Boekholdt SM, Sacks FM, Jukema JW, Shepherd J, Freeman DJ, et al. (2005) Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. Circulation 111: 278-287.
    • (2005) Circulation , vol.111 , pp. 278-287
    • Boekholdt, S.M.1    Sacks, F.M.2    Jukema, J.W.3    Shepherd, J.4    Freeman, D.J.5
  • 19
    • 53149130612 scopus 로고    scopus 로고
    • Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences
    • Lira ME, Loomis AK, Paciga SA, Lloyd DB, Thompson JF, (2008) Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences. J Lipid Res 49: 1955-1962.
    • (2008) J Lipid Res , vol.49 , pp. 1955-1962
    • Lira, M.E.1    Loomis, A.K.2    Paciga, S.A.3    Lloyd, D.B.4    Thompson, J.F.5
  • 20
    • 34548837731 scopus 로고    scopus 로고
    • CETP genotypes and HDL-cholesterol phenotypes in the HERITAGE Family Study
    • Spielmann N, Leon AS, Rao DC, Rice T, Skinner JS, et al. (2007) CETP genotypes and HDL-cholesterol phenotypes in the HERITAGE Family Study. Physiol Genomics 31: 25-31.
    • (2007) Physiol Genomics , vol.31 , pp. 25-31
    • Spielmann, N.1    Leon, A.S.2    Rao, D.C.3    Rice, T.4    Skinner, J.S.5
  • 21
    • 24944570257 scopus 로고    scopus 로고
    • Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study
    • Frisdal E, Klerkx AH, Le Goff W, Tanck MW, Lagarde JP, et al. (2005) Functional interaction between-629C/A,-971G/A and-1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study. Hum Mol Genet 14: 2607-2618.
    • (2005) Hum Mol Genet , vol.14 , pp. 2607-2618
    • Frisdal, E.1    Klerkx, A.H.2    Le Goff, W.3    Tanck, M.W.4    Lagarde, J.P.5
  • 22
    • 34147116766 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease
    • McCaskie PA, Beilby JP, Chapman CM, Hung J, McQuillan BM, et al. (2007) Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease. Hum Genet 121: 401-411.
    • (2007) Hum Genet , vol.121 , pp. 401-411
    • McCaskie, P.A.1    Beilby, J.P.2    Chapman, C.M.3    Hung, J.4    McQuillan, B.M.5
  • 24
    • 73649103089 scopus 로고    scopus 로고
    • Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis
    • Chasman DI, Pare G, Mora S, Hopewell JC, Peloso G, et al. (2009) Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. PLoS Genet 5: e1000730.
    • (2009) PLoS Genet , vol.5
    • Chasman, D.I.1    Pare, G.2    Mora, S.3    Hopewell, J.C.4    Peloso, G.5
  • 25
    • 72149100752 scopus 로고    scopus 로고
    • Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip
    • Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, et al. (2009) Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Am J Hum Genet 85: 628-642.
    • (2009) Am J Hum Genet , vol.85 , pp. 628-642
    • Talmud, P.J.1    Drenos, F.2    Shah, S.3    Shah, T.4    Palmen, J.5
  • 26
    • 0026513630 scopus 로고
    • Alternative splicing of the mRNA encoding the human cholesteryl ester transfer protein
    • Inazu A, Quinet E, Wang S, Brown M, Stevenson S, et al. (1992) Alternative splicing of the mRNA encoding the human cholesteryl ester transfer protein. Biochemistry 31: 2352-2358.
    • (1992) Biochemistry , vol.31 , pp. 2352-2358
    • Inazu, A.1    Quinet, E.2    Wang, S.3    Brown, M.4    Stevenson, S.5
  • 27
    • 17544371811 scopus 로고    scopus 로고
    • Alternative splicing of the human cholesteryl ester transfer protein gene in transgenic mice. Exon exclusion modulates gene expression in response to dietary or developmental change
    • Yang T, Agellon L, Walsh A, Breslow J, Tall A, (1996) Alternative splicing of the human cholesteryl ester transfer protein gene in transgenic mice. Exon exclusion modulates gene expression in response to dietary or developmental change. J Biol Chem 271: 12603-12609.
    • (1996) J Biol Chem , vol.271 , pp. 12603-12609
    • Yang, T.1    Agellon, L.2    Walsh, A.3    Breslow, J.4    Tall, A.5
  • 28
    • 0030778456 scopus 로고    scopus 로고
    • Alternative splicing of human plasma cholesteryl ester transfer protein mRNA in Caco-2 cells and its modulation by oleic acid
    • Dessi M, Motti C, Cortese C, Leonardis E, Giovannini C, et al. (1997) Alternative splicing of human plasma cholesteryl ester transfer protein mRNA in Caco-2 cells and its modulation by oleic acid. Mol Cell Biochem 177: 107-112.
    • (1997) Mol Cell Biochem , vol.177 , pp. 107-112
    • Dessi, M.1    Motti, C.2    Cortese, C.3    Leonardis, E.4    Giovannini, C.5
  • 30
    • 38049172954 scopus 로고    scopus 로고
    • Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory
    • Zhang Y, Bertolino A, Fazio L, Blasi G, Rampino A, et al. (2007) Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory. Proc Natl Acad Sci U S A 104: 20552-20557.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20552-20557
    • Zhang, Y.1    Bertolino, A.2    Fazio, L.3    Blasi, G.4    Rampino, A.5
  • 31
    • 0032231919 scopus 로고    scopus 로고
    • A point mutation in an intronic branch site results in aberrant splicing of COL5A1 and in Ehlers-Danlos syndrome type II in two British families
    • Burrows NP, Nicholls AC, Richards AJ, Luccarini C, Harrison JB, et al. (1998) A point mutation in an intronic branch site results in aberrant splicing of COL5A1 and in Ehlers-Danlos syndrome type II in two British families. Am J Hum Genet 63: 390-398.
    • (1998) Am J Hum Genet , vol.63 , pp. 390-398
    • Burrows, N.P.1    Nicholls, A.C.2    Richards, A.J.3    Luccarini, C.4    Harrison, J.B.5
  • 32
    • 56449118853 scopus 로고    scopus 로고
    • HDL-cholesterol levels and cardiovascular risk: acCETPing the context
    • Lange RA, Lindsey ML, (2008) HDL-cholesterol levels and cardiovascular risk: acCETPing the context. Eur Heart J 29: 2708-2709.
    • (2008) Eur Heart J , vol.29 , pp. 2708-2709
    • Lange, R.A.1    Lindsey, M.L.2
  • 33
    • 0025851782 scopus 로고
    • Health inequalities among British civil servants: the Whitehall II study
    • Marmot MG, Smith GD, Stansfeld S, Patel C, North F, et al. (1991) Health inequalities among British civil servants: the Whitehall II study. Lancet 337: 1387-1393.
    • (1991) Lancet , vol.337 , pp. 1387-1393
    • Marmot, M.G.1    Smith, G.D.2    Stansfeld, S.3    Patel, C.4    North, F.5
  • 34
    • 0345492460 scopus 로고    scopus 로고
    • A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial
    • Pepine CJ, Handberg EM, Cooper-DeHoff RM, Marks RG, Kowey P, et al. (2003) A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial. Jama 290: 2805-2816.
    • (2003) Jama , vol.290 , pp. 2805-2816
    • Pepine, C.J.1    Handberg, E.M.2    Cooper-DeHoff, R.M.3    Marks, R.G.4    Kowey, P.5
  • 35
    • 34547919927 scopus 로고    scopus 로고
    • KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST)
    • Beitelshees AL, Gong Y, Wang D, Schork NJ, Cooper-Dehoff RM, et al. (2007) KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST). Pharmacogenet Genomics 17: 719-729.
    • (2007) Pharmacogenet Genomics , vol.17 , pp. 719-729
    • Beitelshees, A.L.1    Gong, Y.2    Wang, D.3    Schork, N.J.4    Cooper-Dehoff, R.M.5
  • 36
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller S, Dykes D, Polesky H, (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.1    Dykes, D.2    Polesky, H.3
  • 37
    • 0038666509 scopus 로고    scopus 로고
    • Single nucleotide polymorphism genotyping using allele-specific PCR and fluorescence melting curves
    • Papp A, Pinsonneault J, Cooke G, Sadee W, (2003) Single nucleotide polymorphism genotyping using allele-specific PCR and fluorescence melting curves. Biotechniques 34: 1068-1072.
    • (2003) Biotechniques , vol.34 , pp. 1068-1072
    • Papp, A.1    Pinsonneault, J.2    Cooke, G.3    Sadee, W.4
  • 38
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: a tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5


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