Vaporized perfluorocarbon confers protection against acute lung injury by inhibiting MMP-9 expression without protective effects in other organs

Journal of International Medical Research

Volumn 40, Issue 1, 2012, Pages 115-125

  Han, B ^a   Zhao, X ^b   Huang, X ^b   Xie, Lixin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

Acute lung injury; Matrix Metalloproteinase 9 (MMP 9); Multiple organ injury; Perfluorocarbon

Indexed keywords

FLUOROCARBON; GELATINASE B; MESSENGER RNA; SEA WATER;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; HISTOPATHOLOGY; INTESTINE INJURY; INTESTINE PROTECTION; KIDNEY INJURY; KIDNEY PARENCHYMA; LIVER INJURY; LIVER PARENCHYMA; LIVER PROTECTION; LUNG LAVAGE; LUNG PARENCHYMA; LUNG PROTECTION; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PROPHYLAXIS; PROTEIN EXPRESSION; RABBIT; RENAL PROTECTION; SMALL INTESTINE;

EID: 84863257882     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001204000112     Document Type: Article

References (45)

1. Salomez F, Vincent JL: Drowning: a review of epidemiology, pathophysiology, treatment and prevention. Resuscitation 2004; 63: 261-268.
2. Layon AJ, Modell JH: Drowning: update 2009. Anesthesiology 2009; 110: 1390-1401.
3. Ware LB, Matthay MA: The acute respiratory distress syndrome. N Engl J Med 2000; 342: 1334-1349.
4. Tsushima K, King LS, Aggarwal NR, et al: Acute lung injury review. Intern Med 2009; 48: 621-630.
5. Zambon M, Vincent JL: Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest 2008; 133: 1120-1127.
6. Bleyl JU, Ragaller M, Tschö U, et al: Vaporized perfluorocarbon improves oxygenation and pulmonary function in an ovine model of acute respiratory distress syndrome. Anesthesiology 1999; 91: 461-469.
7. Hübler M, Souders JE, Shade ED, et al: Effects of vaporized perfluorocarbon on pulmonary blood flow and ventilation/perfusion distribution in a model of acute respiratory distress syndrome. Anesthesiology 2001; 95: 1414-1421.
8. Zhao XW, Zhang JP, Huang X, et al: Effects of vaporized perfluorocarbon therapy on seawater respiratory distress syndrome in rabbit models. Zhonghua Jie He He Hu Xi Za Zhi 2010; 33: 169-173 [in Chinese, English abstract].
9. Nesti FD, Fuhrman BP, Steinhorn DM, et al: Perfluorocarbon-associated gas exchange in gastric aspiration. Crit Care Med 1994; 22: 1445-1452.
10. Leach CL, Fuhrman BP, Morin FC 3rd, et al: Perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome: a prospective, randomized, controlled study. Crit Care Med 1993; 21: 1270-1278.
11. Papo MC, Paczan PR, Fuhrman BP, et al: Perfluorocarbon-associated gas exchange improves oxygenation, lung mechanics, and survival in a model of adult respiratory distress syndrome. Crit Care Med 1996; 24: 466-474.
12. Baba A, Kim YK, Zhang H, et al: Perfluorocarbon blocks tumor necrosis factor-α-induced interleukin-8 release from alveolar epithelial cells in vitro. Crit Care Med 2000; 28: 1113-1118.
13. Koch T, Ragaller M, Haufe D, et al: Perfluorohexane attenuates proinflammatory and procoagulatory response of activated monocytes and alveolar macrophages. Anesthesiology 2001: 94: 101-109.
14. Nakstad B, Wolfson MR, Shaffer TH, et al: Perfluorochemical liquids modulate cellmediated inflammatory responses. Crit Care Med 2001; 29: 1731-1737.
15. Thomassen MJ, Buhrow LT, Wiedemann HP: Perflubron decreases inflammatory cytokine production by human alveolar macrophages. Crit Care Med 1997; 25: 2045-2047.
16. von der Hardt K, Schoof E, Kandler MA, et al: Aerosolized perfluorocarbon suppresses early pulmonary inflammatory response in a surfactant-depleted piglet model. Pediatr Res 2002; 51: 177-182.
17. Warner RL, Bhagavathula N, Nerusu KC, et al: Matrix metalloproteinase in acute inflammation: induction of MMP-3 and MMP-9 in fibroblasts and epithelial cells following exposure to pro-inflammatory mediators in vitro. Exp Mol Pathol 2004; 76: 189-195.
18. Cederqvist K, Janer J, Tervahartiala T, et al: Upregulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat. Pediatr Res 2006; 60: 395-400.
19. Tan RJ, Fattman CL, Niehouse LM, et al: Matrix metalloproteinases promote inflammation and fibrosis in asbestos-induced lung injury in mice. Am J Respir Cell Mol Biol 2006; 35: 289-297.
20. Sen AI, Foronjy RF, Shiomi T, et al: Loss of MMP-13 delays inflammatory response after acute hyperoxic lung injury. Proc Am Thorac Soc 2008; 5: 360-361.
21. Schmalfeldt B, Prechtel D, Härting K, et al: Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer. Clin Cancer Res 2001; 7: 2396-2404.
22. Atkinson JJ, Senior RM: Matrix metallo-proteinase-9 in lung remodeling. Am J Respir Cell Mol Biol 2003; 28: 12-24.
23. Delclaux C, d'Ortho MP, Delacourt C, et al: Gelatinases in epithelial lining fluid of patients with adult respiratory distress syndrome. Am J Physiol 1997; 272: L442-L451.
24. Lemjabbar H, Gosset P, Lamblin C, et al: Contribution of 92 kDa gelatinase/type IV collagenase in bronchial inflammation during status asthmaticus. Am J Respir Crit Care Med 1999; 159: 1298-1307.
25. Lemjabbar H, Gosset P, Lechapt-Zalcman E, et al: Overexpression of alveolar macrophage gelatinase B (MMP-9) in patients with idiopathic pulmonary fibrosis: effects of steroid and immunosuppressive treatment. Am J Respir Cell Mol Biol 1999; 20: 903-913.
26. Doroszko A, Hurst TS, Polewicz D, et al: Effects of MMP-9 inhibition by doxycycline on proteome of lungs in high tidal volume mechanical ventilation-induced acute lung injury. Proteome Sci 2010; 8: 3.
27. Xinmin D, Yunyou D, Chaosheng P, et al: Dexamethasone treatment attenuates early seawater instillation-induced acute lung injury in rabbits. Pharmacol Res 2006; 53: 372-379.
28. Folkesson HG, Kheradmand F, Matthay MA: The effect of salt water on alveolar epithelial barrier function. Am J Respir Crit Care Med 1994; 150: 1555-1563.
29. Derks CM, Jacobovitz-Derks D: Embolic pneumopathy induced by oleic acid. A systematic morphologic study. Am J Pathol 1977; 87: 143-158.
30. Schlag G, Redl H, van Vuuren CJ, et al: Hyperdynamic sepsis in baboons: II. Relation of organ damage to severity of sepsis evaluated by a newly developed morphological scoring system. Circ Shock 1992; 38: 253-263.
31. Zhang XP, Zhang L, Wang Y, et al: Study of the protective effects of dexamethasone on multiple organ injury in rats with severe acute pancreatitis. JOP 2007; 8: 400-412.
32. Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29: e45.
33. Herrera MT, Toledo C, Valladares F, et al: Positive end-expiratory pressure modulates local and systemic inflammatory responses in a sepsis-induced lung injury model. Intensive Care Med 2003; 29: 1345-1353.
34. Nakazawa K, Yokoyama K, Yamakawa N, et al: Effect of positive end-expiratory pressure on inflammatory response in oleic acid-induced lung injury and whole-lung lavage-induced lung injury. J Anesth 2007; 21: 47-54.
35. Vincent JL, Zambon M: Why do patients who have acute lung injury/acute respiratory distress syndrome die from multiple organ dysfunction syndrome? Implications for management. Clin Chest Med 2006; 27: 725-731.
36. Fan Q, Zhao P, Li J, et al: 17:-Estradiol administration attenuates seawater aspirationinduced acute lung injury in rats. Pulm Pharmacol Ther 2011; 24: 673-681.
37. Shaffer TH, Wolfson MR, Greenspan JS, et al: Liquid ventilation in premature lambs: uptake, biodistribution and elimination of perfluorodecalin liquid. Reprod Fertil Dev 1996; 8: 409-416.
38. Gregor T, Schmalisch G, Burkhardt W, et al: Aerosolization of perfluorocarbons during mechanical ventilation: an in vitro study. Intensive Care Med 2003; 29: 1354-1360.
39. D'Ortho MP, Jarreau PH, Delacourt C, et al: Matrix metalloproteinase and elastase activities in LPS-induced acute lung injury in guinea pigs. Am J Physiol 1994; 266: L209-L216.
40. Ohno I, Ohtani H, Nitta Y, et al: Eosinophils as a source of matrix metalloproteinase-9 in asthmatic airway inflammation. Am J Respir Cell Mol Biol 1997; 16: 212-219.
41. Trocmé C, Gaudin P, Berthier S, et al: Human B lymphocytes synthesize the 92-kDa gelatinase, matrix metalloproteinase-9. J Biol Chem 1998; 273: 20677-20684.
42. Partridge CA, Jeffrey JJ, Malik AB: A 96-kDa gelatinase induced by TNF-alpha contributes to increased microvascular endothelial permeability. Am J Physiol 1993; 265: L438-L447.
43. Buisson AC, Zahm JM, Polette M, et al: Gelatinase B is involved in the in vitro wound repair of human respiratory epithelium. J Cell Physiol 1996; 166: 413-426.
44. Smith TM, Steinhorn DM, Thusu K, et al: A liquid perfluorochemical decreases the in vitro production of reactive oxygen species by alveolar macrophages. Crit Care Med 1995; 23: 1533-1539.
45. Fernandez R, Sarma V, Younkin E, et al: Exposure to perflubron is associated with decreased Syk phosphorylation in human neutrophils. J Appl Physiol 2001; 91: 1941-1947.