MicroRNA-155 silencing inhibits proliferation and migration and induces apoptosis by upregulating BACH1 in renal cancer cells

Molecular Medicine Reports

Volumn 5, Issue 4, 2012, Pages 949-954

  Li, Songchao ^a   Chen, Tieding ^b   Zhong, Zhaohui ^a   Wang, Yi ^a   Li, Yangle ^c   Zhao, Xiaokun ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Lihui Li Hospital   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

BACH1; microRNA 155; Renal cancer

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CYTOKINE; MICRORNA; PROTEIN BACH1; UNCLASSIFIED DRUG;

ADULT; AGED; APOPTOSIS; ARTICLE; BIOINFORMATICS; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; DOWN REGULATION; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; SIGNAL TRANSDUCTION; UPREGULATION;

AGED; APOPTOSIS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; GENE SILENCING; HUMANS; KIDNEY NEOPLASMS; MICRORNAS; MIDDLE AGED; OLIGONUCLEOTIDES, ANTISENSE; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; UP-REGULATION;

EID: 84863245942     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.779     Document Type: Article

References (38)

1. Rini BI, Campbell SC and Escudier B: Renal cell carcinoma. Lancet 373: 1119-1132, 2009.
2. Jemal A, Siegel R, Xu J and Ward E: Cancer statistics, 2010. CA Cancer J Clin 60: 277-300, 2010.
3. Reeves DJ and Liu CY: Treatment of metastatic renal cell carcinoma. Cancer Chemother Pharmacol 64: 11-25, 2009.
4. Bartel DP: Target recognition and regulatory functions. Cell 136: 215-233, 2009.
5. Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, Thomson AM, Lim B and Rigoutsos I: A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes. Cell 126: 1203-1217, 2006. (Pubitemid 44380294)
6. Asangani IA, Rasheed S, Nikolova D, Leupold JH, Colburn NH, Post S and Allgayer H: MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2236, 2008.
7. Navarro A, Diaz T, Martinez A, et al: Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma. Blood 114: 2945-2951, 2009.
8. Tsuchiya S, Fujiwara T, Sato F, Shimada Y, Tanaka E, Sakai Y, Shimizu K and Tsujimoto G: MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1). J Biol Chem 286: 420-428, 2011.
9. Jiang S, Zhang HW, Lu MH, He XH, Li Y, Gu H, Liu MF and Wang ED: MicroRNA-155 functions as an oncomir in breast cancer by targeting the suppressor of cytokine signaling 1 gene. Cancer Res 70: 3119-3127, 2010.
10. Du ZM, Hu LF, Wang HY, Yan LX, Zeng YX, Shao JY and Ernberg I: Upregulation of miR-155 in nasopharyngeal carcinoma is partly driven by LMP1 and LMP2A and downregulates a negative prognostic marker JMJD1A. PLoS One 6: e19137, 2011.
11. Pedersen IM, Otero D, Kao E, Miletic AV, Hother C, Ralfkiaer E, Rickert RC, Gronbaek K and David M: Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas. EMBO Mol Med 1: 288-295, 2009.
12. Zhao Y, Xu H, Yao Y, Smith LP, Kgosana L, Green J, Petherbridge L, Baigent SJ and Nair V: Critical role of the virus-encoded microRNA-155 ortholog in the induction of Marek's disease lymphomas. PLoS Pathog 7: e1001305, 2011.
13. Shibuya H, Iinuma H, Shimada R, Horiuchi A and Watanabe T: Clinicopathological and prognostic value of microRNA-21 and microRNA-155 in colorectal cancer. Oncology 79: 313-320, 2010.
14. Kong W, Yang H, He L, Zhao JJ, Coppola D, Dalton WS and Cheng JQ: MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RHOA. Mol Cell Biol 28: 6773-6784, 2008.
15. Wang B, Majumder S, Nuovo G, et al: Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. Hepatology 50: 1152-1161, 2009.
16. Levati L, Pagani E, Romani S, et al: MicroRNA-155 targets the ski gene in human melanoma cell lines. Pigment Cell Melanoma Res 24: 538-550, 2011.
17. Neal CS, Michael MZ, Rawlings LH, Van der Hoek MB and Gleadle JM: The VHL-dependent regulation of microRNAs in renal cancer. BMC Med 8: 64, 2010.
18. White NM, Bao TT, Grigull J, et al: MiRNA profiling for clear cell renal cell carcinoma: biomarker discovery and identification of potential controls and consequences of miRNA dysregulation. J Urol 186: 1077-1083, 2011.
19. Juan D, Alexe G, Antes T, Liu H, Madabhushi A, Delisi C, Ganesan S, Bhanot G and Liou LS: Identification of a microRNA panel for clear-cell kidney cancer. Urology 75: 835-841,2010.
20. Chen C, Ridzon D, Broomer AJ, et al: Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 27: e179, 2005.
21. Warnatz JH, Schmidt D, Manke T, et al: The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. J Biol Chem 286: 23521-23532, 2011.
22. Bakirtzi K, Hatziapostolou M, Karagiannides I, Polytarchou C, Jaeger S, Iliopoulos D and Pothoulakis C: Neurotensin signaling activates microRNAs -21 and -155 and akt, promotes tumor growth in mice, and is increased in human colon tumors. Gastroenterology 141: 1749-1761, 2011.
23. Crawford M, Brawner E, Batte K, Yu L, Hunter MG, Ga O, Nuovo G, Marsh CB and Sinkam SP: MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines. Biochem Biophys Res Commun 373: 607-612, 2008.
24. Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL and Massagué J: Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451: 147-152, 2008.
25. Elmén J, Lindow M, Schütz S, et al: LNA-mediated microRNA silencing in non-human primates. Nature 452: 896-899, 2008. (Pubitemid 351550859)
26. Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, Munk ME, Kauppinen S and Ørum H: Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327: 198-201, 2010.
27. Okada S, Muto A, Ogawa E, Nakanome A, Katoh Y, Ikawa S, Aiba S, Igarashi K and Okuyama R: Bach1-dependent and -independent regulation of HEME oxygenase-1 in keratinocytes. J Biol Chem 285: 23581-23589, 2010.
28. Igarashi K and Sun J: The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. Antioxid Redox Signal 8: 107-118, 2006. (Pubitemid 43324536)
29. Jozkowicz A, Was H and Dulak J: HEME oxygenase-1 in tumors: is it a false friend? Antioxid Redox Signal 9: 2099-2117, 2007. (Pubitemid 350059009)
30. Was H, Dulak J and Jozkowicz A: HEME oxygenase-1 in tumor biology and therapy. Curr Drug Targets 11: 1551-1570, 2010.
31. Miyazaki T, Kirino Y, Takeno M, et al: Expression of HEME oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1. Cancer Sci 101: 1409-1416, 2010.
32. Datta D, Banerjee P, Gasser M, Waaga AG and Pal S: CXCR3-B can mediate growth-inhibitory signals in human renal cancer cells by down-regulating the expression of HEME oxygenase-1. J Biol Chem 285: 33684-36842, 2010.
33. Kong W, He L, Coppola M, Guo J, Esposito NN, Coppola D and Cheng JQ: MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. J Biol Chem 285: 17869-17879, 2010.
34. Rai D, Kim SW, McKeller MR, Dahia PL and Aguiar RC: Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. Proc Natl Acad Sci USA 107: 3111-3116, 2010.
35. Lee JW, Bae SH, Jeong JW, Kim SH and Kim KW: Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med 36: 1-12, 2004.
36. Khan MN, Bhattacharyya T, Andrikopoulos P, Esteban M, Barod R, Connor T, Ashcroft M, Maxwell PH and Kiriakidis S: Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis. Br J Cancer 104: 1151-1159, 2011.
37. Inomata M, Tagawa H, Guo YM, Kameoka Y, Takahashi N and Sawada K: MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 113: 396-402, 2009.
38. Lössner C, Meier J, Warnken U, Rogers M, Lichter P, Pscherer A and Schnölzer M: Quantitative proteomics identify novel miR-155 target proteins. PLoS One 6: 22146, 2011.