Postexposure treatment with the live-attenuated rabies virus (rv) Vaccine trigas triggers the clearance of wild-type rv from the central nervous system (cns) Through the rapid induction of genes relevant to adaptive immunity in cns tissues

Journal of Virology

Volumn 86, Issue 6, 2012, Pages 3200-3210

  Li, Jianwei ^a   Ertel, Adam ^a   Portocarrero, Carla ^a   Barkhouse, Darryll A ^a   Dietzschold, Bernhard ^a   Hooper, D Craig ^a   Faber, Milosz ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTERFERON; BETA1 INTERFERON; GAMMA INTERFERON; INTERFERON; LIVE ATTENUATED TRIPLE GLYCOPROTEIN RABIES VIRUS VARIANT; MESSENGER RNA; RABIES VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM INFECTION; CHEMOKINE LIGAND 3 GENE; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; GENE; GENE ACTIVATION; GENE CLUSTER; GENE DOSAGE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE INDUCTION; GENE PRODUCT; GRANZYME A GENE; IMMUNE RESPONSE GENE; INNATE IMMUNITY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NATURAL KILLER CELL ACTIVATOR 2 GENE; NONHUMAN; POLYMERASE CHAIN REACTION; POST EXPOSURE PROPHYLAXIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; RABIES; RABIES VIRUS; T LYMPHOCYTE ACTIVATION; TYPE 1 INTERFERON GENE; VIRAL CLEARANCE; VIRUS REPLICATION; VIRUS SURVIVAL;

ADAPTIVE IMMUNITY; ANIMALS; ANTIBODIES, VIRAL; CENTRAL NERVOUS SYSTEM; FEMALE; HUMANS; MICE; MICE, INBRED C57BL; POST-EXPOSURE PROPHYLAXIS; RABIES; RABIES VACCINES; RABIES VIRUS; UP-REGULATION; VACCINES, ATTENUATED;

MUS; RABIES VIRUS;

EID: 84863244273     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06699-11     Document Type: Article

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