SCOPUS 정보 검색 플랫폼

Volumn 55, Issue 5, 2012, Pages 2452-2468

2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one derivatives as potent and selective histamine-3 receptor antagonists

(14) Zhou, Dahui a Gross, Jonathan L a Adedoyin, Adedayo B a Aschmies, Suzan B a Brennan, Julie a Bowlby, Mark a Di, Li a Kubek, Katie a Platt, Brian J a Wang, Zheng a Zhang, Guoming a Brandon, Nicholas a Comery, Thomas A a Robichaud, Albert J a

a PFIZER INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE H3 RECEPTOR ANTAGONIST; ION CHANNEL; N,N DIMETHYL 4 [1 OXO 2 (2 PYRROLIDIN 1 YLETHYL) 1,2,3,4 TETRAHYDROISOQUINOLIN 6 YL]BENZAMIDE; NEUROTRANSMITTER RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG MEGADOSE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; RAT; SINGLE DRUG DOSE;

ANIMALS; BENZAMIDES; BLOOD PROTEINS; CELL LINE; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; DRINKING BEHAVIOR; DRUG INVERSE AGONISM; ETHER-A-GO-GO POTASSIUM CHANNELS; GUINEA PIGS; HISTAMINE AGONISTS; HISTAMINE H3 ANTAGONISTS; HUMANS; ISOQUINOLINES; MACACA FASCICULARIS; MALE; MICROSOMES, LIVER; PERMEABILITY; PROTEIN BINDING; PYRROLIDINES; RADIOLIGAND ASSAY; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; RECEPTORS, HISTAMINE H3; RECOGNITION (PSYCHOLOGY); STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84863242786 PISSN: 00222623 EISSN: 15204804 Source Type: Journal
DOI: 10.1021/jm300011d Document Type: Article

Times cited : (16)

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