The absence of Nrf2 enhances NF-κB-dependent inflammation following scratch injury in mouse primary cultured astrocytes

Mediators of Inflammation

Volumn 2012, Issue , 2012, Pages

  Pan, Hao ^a   Wang, Handong ^a   Wang, Xiaoliang ^a   Zhu, Lin ^a   Mao, Lei ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; NFE2L2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; IN VITRO STUDY; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCRATCHING; TRAUMATIC BRAIN INJURY; UPREGULATION; WILD TYPE; ZYMOGRAPHY; ANIMAL; BIOSYNTHESIS; CELL COUNT; CELL CULTURE; CELL DEATH; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; METHODOLOGY; MOUSE MUTANT; WOUND HEALING;

MUS;

ANIMALS; ASTROCYTES; CELL COUNT; CELL DEATH; CELLS, CULTURED; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; NF-KAPPA B; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; WOUND HEALING;

EID: 84863238189     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2012/217580     Document Type: Article

References (29)

1. Stahel P. F., Shohami E., Younis F. M., Kariya K., Otto V. I., Lenzlinger P. M., Grosjean M. B., Eugster H. P., Trentz O., Kossmann T., Morganti-Kossmann M. C., Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines Journal of Cerebral Blood Flow and Metabolism 2000 20 2 369 380 (Pubitemid 30108456)
2. Hang C. H., Shi J. X., Li J. S., Wu W., Yin H. X., Concomitant upregulation of nuclear factor- B activity, proinflammatory cytokines and ICAM-1 in the injured brain after cortical contusion trauma in a rat model Neurology India 2005 53 3 312 317 (Pubitemid 41526843)
3. Hang C. H., Shi J. X., Li J. S., Li W. Q., Wu W., Expressions of intestinal NF- B, TNF-, and IL-6 following traumatic brain injury in rats Journal of Surgical Research 2005 123 2 188 193 (Pubitemid 40186896)
4. Jin W., Zhu L., Guan Q., Chen G., Qing F. W., Hong X. Y., Chun H. H., Ji X. S., Han D. W., Influence of Nrf2 genotype on pulmonary NF- B activity and inflammatory response after traumatic brain injury Annals of Clinical and Laboratory Science 2008 38 3 221 227
5. Jin W., Wang H., Yan W., Zhu L., Hu Z., Ding Y., Tang K., Role of Nrf2 in protection against traumatic brain injury in mice Journal of Neurotrauma 2009 26 1 131 139
6. Hong Y., Yan W., Chen S., Sun C. R., Zhang J. M., The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice Acta Pharmacologica Sinica 2010 31 11 1421 1430
7. Yu A. C., Lee Y. L., Eng L. F., Astrogliosis in culture: I. The model and the effect of antisense oligonucleotides on glial fibrillary acidic protein synthesis Journal of Neuroscience Research 1993 34 3 295 303 (Pubitemid 23060114)
8. Venetsanou K., Vlachos K., Moles A., Fragakis G., Fildissis G., Baltopoulos G., Hypolipoproteinemia and hyperinflammatory cytokines in serum of severe and moderate traumatic brain injury (TBI) patients European Cytokine Network 2007 18 4 206 209
9. Bethea J. R., Castro M., Keane R. W., Lee T. T., Dietrich W. D., Yezierski R. P., Traumatic spinal cord injury induces nuclear factor- B activation Journal of Neuroscience 1998 18 9 3251 3260 (Pubitemid 28186018)
10. Li B., Mahmood A., Lu D., Wu H., Xiong Y., Qu C., Chopp M., Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1B level after traumatic brain injury Neurosurgery 2009 65 1 179 185
11. Thompson W. L., van Eldik L. J., Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NF B and MAPK dependent pathways in rat astrocytes Brain Research 2009 1287 47 57
12. Gottschall P. E., Deb S., Regulation of matrix metalloproteinase expression in astrocytes, microglia and neurons NeuroImmunoModulation 1996 3 2-3 69 75 (Pubitemid 26373860)
13. Rosenberg G. A., Estrada E. Y., Dencoff J. E., Stetler-Stevenson W. G., Tumor necrosis factor- -induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window Brain Research 1995 703 1-2 151 155 (Pubitemid 3013581)
14. Hsu C.-P., Chen Y.-L., Huang C.-C., Chou C.-C., Liu C.-L., Hung C.-H., Kao T.-Y., Chung Y.-C., Anti-interleukin-6 receptor antibody inhibits the progression in human colon carcinoma cells European Journal of Clinical Investigation 2011 41 3 277 284
15. Srinivasan D., Yen J. H., Joseph D. J., Friedman W., Cell type-specific interleukin-1 signaling in the CNS Journal of Neuroscience 2004 24 29 6482 6488 (Pubitemid 38971695)
16. Kemler I., Fontana A., Role of I B and I B in the biphasic nuclear translocation of NF- B in TNF -stimulated astrocytes and in neuroblastoma cells Glia 1999 26 3 212 220 (Pubitemid 29212039)
17. Yan W., Wang H. D., Feng X. M., Ding Y. S., Jin W., Tang K., The expression of NF-E2-related factor 2 in the rat brain after traumatic brain injury The Journal of trauma 2009 66 5 1431 1435
18. Yan W., Wang H. D., Hu Z. G., Wang Q. F., Yin H. X., Activation of Nrf2-ARE pathway in brain after traumatic brain injury Neuroscience Letters 2008 431 2 150 154
19. Dash P. K., Zhao J., Orsi S. A., Zhang M., Moore A. N., Sulforaphane improves cognitive function administered following traumatic brain injury Neuroscience Letters 2009 460 2 103 107
20. Jin W., Wang H., Yan W., Xu L., Wang X., Zhao X., Yang X., Chen G., Ji Y., Disruption of Nrf2 enhances upregulation of nuclear factor- B activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury Mediators of Inflammation 2008 2008
21. Xu C., Shen G., Chen C., Gélinas C., Kong A. N. T., Suppression of NF- B and NF- B-regulated gene expression by sulforaphane and PEITC through I B, IKK pathway in human prostate cancer PC-3 cells Oncogene 2005 24 28 4486 4495 (Pubitemid 41032612)
22. Jeong W. S., Kim I. W., Hu R., Kong A. N., Modulatory properties of various natural chemopreventive agents on the activation of NF- B signaling pathway Pharmaceutical Research 2004 21 4 661 670 (Pubitemid 38457289)
23. Jin W., Wang H. D., Hu Z. G., Yan W., Chen G., Yin H. X., Transcription factor Nrf2 plays a pivotal role in protection against traumatic brain injury-induced acute intestinal mucosal injury in mice Journal of Surgical Research 2009 157 2 251 260
24. Thimmulappa R. K., Lee H., Rangasamy T., Reddy S. P., Yamamoto M., Kensler T. W., Biswal S., Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis Journal of Clinical Investigation 2006 116 4 984 995
25. Liu G. H., Qu J., Shen X., NF- B/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK Biochimica et Biophysica Acta 2008 1783 5 713 727
26. Hu R., Saw C. L., Yu R., Kong A. N., Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: antioxidant coupled with antiinflammatory Antioxidants and Redox Signaling 2010 13 11 1679 1698
27. Sawada M., Suzumura A., Marunouchi T., Cytokine network in the central nervous system and its roles in growth and differentiation of glial and neuronal cells International Journal of Developmental Neuroscience 1995 13 3-4 253 264
28. Pan H., Wang H., Zhu L., Mao L., Qiao L., Su X., Depletion of Nrf2 enhances inflammation induced by oxyhemoglobin in cultured mice astrocytes Neurochemical Research 2011 36 12 2434 2441
29. Sohn Y., Kang H. C., Kim K. S., Park S. M., Sohn N. W., Jung H. S., Kim S. H., Protective effects of Natrii sulfas on cerebral focal ischemia induced by MCAO in rats American Journal of Chinese Medicine 2009 37 2 273 293