Identifying therapeutic targets in a combined EGFR-TGFβR signalling cascade using a multiscale agent-based cancer model

Mathematical Medicine and Biology

Volumn 29, Issue 1, 2012, Pages 95-108

  Wang, Zhihui ^a   Bordas, Veronika ^b   Sagotsky, Jonathan ^a   Deisboeck, Thomas S ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

Agent based model; Epidermal growth factor receptor; Multiscale; Non small cell lung cancer; Signalling pathway; Transforming growth factor

Indexed keywords

BIOLOGICAL ORGANS; COMPUTATIONAL METHODS; DISEASES; ENZYME ACTIVITY; ENZYME INHIBITION; SIGNALING;

AGENT-BASED MODEL; CANCER MODELS; EPIDERMAL GROWTH FACTOR RECEPTORS; MULTISCALE; NON SMALL CELL LUNG CANCER; RECEPTOR SIGNALING; SIGNALLING PATHWAYS; THERAPEUTIC TARGETS; TRANSFORMING GROWTH FACTOR Β; TRANSFORMING GROWTH FACTORS;

CELL SIGNALING;

EID: 84863229594     PISSN: 14778599     EISSN: 14778602     Source Type: Journal    
DOI: 10.1093/imammb/dqq023     Document Type: Article

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