Early radiation-induced mucosal changes evaluated by proctoscopy: Predictive role of dosimetric parameters

Radiotherapy and Oncology

Volumn 104, Issue 1, 2012, Pages 103-108

  Ippolito, Edy ^a,c   Deodato, Francesco ^a   MacChia, Gabriella ^a   Massaccesi, Mariangela ^a   Digesù, Cinzia ^a   Pirozzi, Giuseppe A ^a   Spera, Gianluca ^a   Marangi, Stefania ^a   Annoscia, Emanuele ^a   Cilla, Savino ^a   Piermattei, Angelo ^a   Valentini, Vincenzo ^b   Cellini, Numa ^b   Ingrosso, Marcello ^a   Morganti, Alessio Giuseppe ^a,b  

^a CATHOLIC UNIVERSITY   (Italy)

^b FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^c UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

Late rectal toxicity; Prostate cancer; Rectoscopy

Indexed keywords

ADULT; ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC TEST ACCURACY STUDY; DOSIMETRY; EARLY DIAGNOSIS; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE CARE; PREDICTIVE VALIDITY; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; RECEIVER OPERATING CHARACTERISTIC; RECTOSCOPY; RECTUM DISEASE; RECTUM MUCOSA; SCORING SYSTEM; TELANGIECTASIA;

ADENOCARCINOMA; AGED; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; PROCTOSCOPY; PROSTATIC NEOPLASMS; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RECTUM; TELANGIECTASIS;

EID: 84863228064     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2012.05.010     Document Type: Article

References (44)

1. J.W. Denham, P.C. O'Brien, and R.H. Dunstan Is there more than one late radiation proctitis syndrome? Aliment Pharmacol Ther 51 1999 43 53 (Pubitemid 29244090)
2. H.J. Andreyev Gastrointestinal symptoms after pelvic radiotherapy: a new understanding to improve management of symptomatic patients Lancet Oncol 8 2007 1007 1017
3. J.D. Cox, J.A. Stetz, and T.F. Pajak Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) Int J Radiat Oncol Biol Phys 31 1995 1341 1346
4. A. Trotti, A.D. Colevas, and A. Setserb CTCAE v3.0. development of a comprehensive grading system for the adverse effects of cancer treatment Semin Radiat Oncol 13 2003 176 181 (Pubitemid 36962641)
5. LENT-SOMA tables. Radiother Oncol 1995;35:17-60.
6. A. Capp, M. Inostroza-Ponta, and D. Bill Is there more than one proctitis syndrome? A revisitation using data from the TROG 96.01 trial Aliment Pharmacol Ther 90 2009 400 407
7. C. Fiorino, G. Fellin, and T. Rancati Clinical and dosimetric predictors of late rectal syndrome after 3D-CRT for localized prostate cancer: preliminary results of a multicenter prospective study Int J Radiat Oncol Biol Phys 70 2008 1130 1137 (Pubitemid 351296107)
8. S.T. Peeters, J.V. Lebesque, and W.D. Heemsbergen Localized volume effects for late rectal and anal toxicity after radiotherapy for prostate cancer Int J Radiat Oncol Biol Phys 64 2006 1151 1161
9. O'Brien PC. Radiation injury of the rectum. Radiother Oncol 2001;60:1-14. (Pubitemid 32532076)
10. S. Wachter, N. Gerstner, G. Goldner, R. Pötzi, A. Wambersie, and R. Pötter Endoscopic scoring of late rectal mucosal damage after conformal radiotherapy for prostatic carcinoma Aliment Pharmacol Ther 54 2000 11 19 (Pubitemid 30055321)
11. K.D. Chi, E.D. Ehrenpreis, and A.B. Jani Accuracy and reliability of the endoscopic classification of chronic radiation-induced proctopathy using a novel grading method J Clin Gastroenterol 39 2005 42 46 (Pubitemid 40041342)
12. R. Zinicola, M.D. Rutter, and G. Falasco Haemorrhagic radiation proctitis: endoscopic severity may be useful to guide therapy Int J Colorectal Dis 18 2003 439 444 (Pubitemid 37062737)
13. M. Crespi, M. Delvaux, M. Schaprio, C. Venables, and F. Zwiebel Working party report by the committee for minimal standards of terminology and documentation in digestive endoscopy of the European society of gastrointestinal endoscopy. Minimal standard terminology for a computerized endoscopic data base. Ad hoc task force of the committee Am J Gastroenterol 91 1996 191 216 (Pubitemid 26067325)
14. G. Goldner, B. Tomicek, and G. Becker Proctitis after external-beam radiotherapy for prostate cancer classified by Vienna Rectoscopy Score and correlated with EORTC/RTOG score for late rectal toxicity: results of a prospective multicenter study of 166 patients Int J Radiat Oncol Biol Phys 67 2007 78 83 (Pubitemid 44959504)
15. G. Goldner, R. Pötter, A. Kranz, A. Bluhm, and W. Dörr Healing of late endoscopic changes in the rectum between 12 and 65 months after external beam radiotherapy Strahlenther Onkol 187 2011 202 205
16. H.J. Andreyev, P. Vlavianos, P. Blake, D. Dearnaley, A.R. Norman, and D. Tait Gastrointestinal symptoms after pelvic radiotherapy: role for the gastroenterologist? Int J Radiat Oncol Biol Phys 62 2005 1464 1471 (Pubitemid 40982071)
17. S. Wachter, N. Gerstner, G. Goldner, R. Pötzi, A. Wambersie, and R. Pötter Rectal sequelae after conformal radiotherapy of prostate cancer: dose-volume histograms as predictive factors Aliment Pharmacol Ther 59 2001 65 70 (Pubitemid 32261078)
18. L.J. Boersma, B.M. Van den, and A.M. Bruce Estimation of the incidence of late bladder and rectum complications after high dose (70-78 Gy) conformal radiotherapy for prostate cancer, using dose-volume histograms Int J Radiat Oncol Biol Phys 41 1998 83 92 (Pubitemid 28211306)
19. C. Fiorino, C. Cozzarini, and V. Vavassori Relationships between DVHs and late rectal bleeding after radiotherapy for prostate cancer: analysis of a large group of patients pooled from three institutions Aliment Pharmacol Ther 64 2002 1 12 (Pubitemid 35223147)
20. C. Greco, C. Mazzetta, and F. Cattani Finding dose-volume constraints to reduce late rectal toxicity following 3D-conformal radiotherapy (3D-CRT) of prostate cancer Aliment Pharmacol Ther 69 2003 215 222 (Pubitemid 37485883)
21. C. Cozzarini, C. Fiorino, and G.L. Ceresoli Significant correlation between rectal DVH and late bleeding in patients treated after radical prostatectomy with conformal or conventional radiotherapy (66.6-70.2 Gy) Int J Radiat Oncol Biol Phys 55 2003 688 694 (Pubitemid 36170010)
22. E.H. Huang, A. Pollack, and L. Levy Late rectal toxicity: dose-volume effects of conformal radiotherapy for prostate cancer Int J Radiat Oncol Biol Phys 54 2002 1314 1321 (Pubitemid 35380030)
23. A. Pollack, G.K. Zagars, and G. Starkschall Prostate cancer radiation dose response: results of the M.D. Anderson phase III randomized trial Int J Radiat Oncol Biol Phys 53 2002 1097 1105 (Pubitemid 34787842)
24. V.S. Khoo, and D.P. Dearnaley Question of dose, fractionation and technique: ingredients for testing hypofractionation in prostate cancer - The CHHiP trial Clin Oncol (R Coll Radiol) 20 2008 12 14
25. H.P. Van der Laan, A. Van den Bergh, C. Schilstra, R. Vlaslam, H. Meertens, and J.A. Langendijk Grading system dependent volume effects for late radiation induced rectal toxicity after curative radiotherapy for prostate cancer Int J Radiat Oncol Biol Phys 70 2008 1145
26. A. Jackson, M.W. Skwarchuk, and M.J. Zelefsky Late rectal bleeding after conformal radiotherapy of prostate cancer: II. Volume effects and dose-volume histograms Int J Radiat Oncol Biol Phys 49 2001 685 698 (Pubitemid 32112195)
27. S.L. Tucker, R. Cheung, and L. Dong Dose-volume response analyses of late rectal bleeding after radiotherapy for prostate cancer Int J Radiat Oncol Biol Phys 59 2004 353 365 (Pubitemid 38622586)
28. M. Roach, C. Marquez, and H. You Predicting the risk of lymph node involvement using the pre-treatment prostate specific antigen and Gleason score in men with clinically localized prostate cancer Int J Radiat Oncol Biol Phys 28 1993 33 37 (Pubitemid 24012852)
29. N. Hovdenak, L.F. Fajardo, and M. Hauer-Jensen Acute radiation proctitis: a sequential clinicopathologic study during pelvic radiotherapy Int J Radiat Oncol Biol Phys 48 2000 1111 1117
30. N. Hovdenak, J. Wang, C.C. Sung, T. Kelly, L.F. Fajardo, and M. Hauer-Jensen Clinical significance of increased gelatinolytic activity in the rectal mucosa during external beam radiation therapy of prostate cancer Int J Radiat Oncol Biol Phys 53 2002 919 927 (Pubitemid 34722637)
31. D. Christie, J. Denham, and A. Steigler Delayed rectal and urinary symptomatology in patients treated for prostate cancer by radiotherapy with or without short term neo-adjuvant androgen deprivation Aliment Pharmacol Ther 77 2005 117 125 (Pubitemid 41682375)
32. P.C. O'Brien, C.S. Hamilton, J.W. Denham, R. Gourlay, and C.I. Franklin Spontaneous improvement in late rectal mucosal changes after radiotherapy for prostate cancer Int J Radiat Oncol Biol Phys 58 2004 75 80 (Pubitemid 38010339)
33. E.N. Van Lin, J. Kristinsson, and M.E. Philippens Reduced late rectal mucosal changes after prostate three-dimensional conformal radiotherapy with endorectal ballon as observed in repeated endoscopy Int J Radiat Oncol Biol Phys 67 2007 799 811 (Pubitemid 46215872)
34. M. Feng, A.L. Hanlon, and T.M. Pisansky Predictive factors for late genitourinary and gastrointestinal toxicity in patients with prostate cancer treated with adjuvant or salvage radiotherapy Int J Radiat Oncol Biol Phys 68 2007 1417 1423 (Pubitemid 47176790)
35. J.G. Taylor, J.A. DiSario, and K.N. Buchi Argon laser therapy for hemorrhagic radiation proctitis: long-term results Gastrointest Endosc 39 1993 641 644 (Pubitemid 23282516)
36. H.R. Williams, P. Vlavianos, P. Blake, D.P. Dearnaley, D. Tait, and H.J.N. Andreyev The significance of rectal bleeding after pelvic radiotherapy Aliment Pharmacol Ther 21 2005 1085 1090 (Pubitemid 40646533)
37. E.M. Moore, T.J. Magrino, and P.A. Johnstone Rectal bleeding after radiation therapy for prostate cancer: endoscopic evaluation Radiology 217 2000 215 218 (Pubitemid 33097604)
38. T. Rancati, C. Fiorino, and G. Gagliardi Fitting late rectal bleeding data using different NTCP models: results from an Italian multi-centric study (AIROPROS0101) Aliment Pharmacol Ther 73 2004 21 32 (Pubitemid 39304121)
39. M. Söhn, D. Yan, J. Linag, E. Meldolesi, C. Vargas, and M. Alber Incidence of late rectal bleeding in high dose conformal radiotherapy of prostate cancer using equivalent uniform dose-based and dose-volume-based normal tissue complication probability models Int J Radiat Oncol Biol Phys 26 2007 1066 1073
40. S.L. Tucker, L. Dong, and W.R. Bosch Fit of a generalized Lyman normal tissue complication probability (NTCP) model to grade ≥2 late rectal toxicity data from patients treated on protocol RTOG 94-06 Int J Radiat Oncol Biol Phys 69 2007 S8 9
41. T. Rancati, C. Fiorino, and V. Valvassori Late rectal bleeding after conformal radiotherapy for prostate cancer: NTCP modelling Aliment Pharmacol Ther 88 2008 S332 3
42. S.L. Gulliford, K. Foo, and R.C. Morgan Dose-volume constraints to reduce rectal side effects from prostate radiotherapy: evidence from MRC RT01 trial ISRCTN 47772397 Int J Radiat Oncol Biol Phys 76 2010 747 754
43. G. Fellin, C. Fiorino, and T. Rancati Clinical and dosimetric predictors of late rectal toxicity after conformal radiation for localized prostate cancer: results of a large multicenter observational study Aliment Pharmacol Ther 93 2009 197 202
44. P. Georg, C. Kirisits, and G. Goldner Correlation of dose-volume parameters, endoscopic and clinical rectal side effects in cervix cancer patients treated with definitive radiotherapy including MRI-based brachytherapy Aliment Pharmacol Ther 91 2009 173 180