Decreased gonadotropin requirements in once daily compared to twice daily administration: A prospective, randomized study

Journal of Assisted Reproduction and Genetics

Volumn 29, Issue 4, 2012, Pages 321-324

  Sharara, Fady I ^a,b   Collins, Michael G ^c   Abdo, Galal ^a  

^a Virginia Center for Reproductive Medicine   (United States)

^b GEORGE WASHINGTON UNIVERSITY   (United States)

^c FERRING PHARMACEUTICALS   (United States)

Author keywords

BID administration; Blastocyst; ET; Gonadotropins; Ovarian stimulation administration; Pregnancy rate

Indexed keywords

ESTRADIOL; GONADOTROPIN; HUMAN MENOPAUSAL GONADOTROPIN;

ADULT; ARTICLE; BLASTOCYST; BODY MASS; COMPARATIVE STUDY; CONTROLLED STUDY; DELIVERY; DOSAGE SCHEDULE COMPARISON; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMAN; OOCYTE; PREGNANCY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

ADULT; DRUG ADMINISTRATION SCHEDULE; EMBRYO TRANSFER; FEMALE; FERTILITY AGENTS, FEMALE; FERTILIZATION IN VITRO; GONADOTROPINS; HUMANS; OOCYTES; OVULATION INDUCTION; PREGNANCY; PREGNANCY RATE; REPRODUCTIVE TECHNIQUES, ASSISTED; SPERM INJECTIONS, INTRACYTOPLASMIC;

EID: 84863227463     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-012-9713-2     Document Type: Article

References (8)

1. Murphy AA, Michelman HW, Riedel HH, Grillo M, Mettler L. Comparison of human menopausal gonadotropin administered once and twice daily in an in vitro fertilization and embryo transfer program. J IVF ET. 1988;5:43-7. (Pubitemid 18097081)
2. Schnell V, Zbella A, Hummel WP, Khan N, Perloe M, Webster BW. Evaluation of QD vs. BID dosing of gonadotropins in patients undergoing IVF. Fertil Steril. 2007;87:S23-4.
3. Sharara FI, Abdo GA. Incidence of monozygotic twins in blastocyst and cleavage stage assisted reproductive technology cycles. Fertil Steril. 2010;93:642-5.
4. Doody KJ, Schnell VL, Foulk RA, Miller CE, Kolb BA, Blake EJ, Yankov VI. Endometrin for luteal support in a randomized, controlled, open-label, prospective in-vitro fertilization trial using a combination of Menopur and Bravelle for controlled ovarian hyperstimulation. Fertil Steril. 2009;91:1012-7.
5. Keye WR, Marrs RP, Check JH, Schnell V, Surrey M, Marshall DC. Evaluation of mixed protocols with Bravelle (human-derived FSH) and Repronex (hMG) to assess clinical efficacy (EMBRACE) in women undergoing in vitro fertilization. Fertil Steril. 2004;82:348-57. (Pubitemid 39092034)
6. Marshall DC, Reike E, Da Silva M, Nardi RV. Mixed-protocol, same-syringe combination of gonadotropins: compatibility of new, highly purified, human-derived FSH (Bravelle) and hMG (Repronex). Today Ther Trends. 2001;19:213-24. (Pubitemid 33104140)
7. Stillman RJ, Richter KS, Banks NK, Graham JR. Elective single embryo transfer: a 6-year progressive implementation of 784 single embryo transfers and the influence of payment method on patient choice. Fertil Steril. 2009;92:1895-906.
8. Resolve: the National Infertility Association. Patient assessment of infertility treatment administration. Results of an online patient survey, Bethesda, MD 2006