A Siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein

Glycobiology

Volumn 22, Issue 8, 2012, Pages 1086-1091

  Rademacher, Christoph ^a   Bru, Thierry ^b   McBride, Ryan ^a   Robison, Elizabeth ^a   Nycholat, Corwin M ^a   Kremer, Eric J ^b   Paulson, James C ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b CNRS   (France)

Author keywords

Adenovirus; Sialic acid; Siglecs; Structural glycobiology

Indexed keywords

CANINE ADENOVIRUS 2 FIBER KNOB PROTEIN; CAPSID PROTEIN; EPITOPE; MEMBRANE RECEPTOR; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; UNCLASSIFIED DRUG;

ARTICLE; CANINE ADENOVIRUS; IMMUNOREGULATION; MICROARRAY ANALYSIS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF;

ADENOVIRUSES, CANINE; ANIMALS; BIOLOGICAL MARKERS; CAPSID PROTEINS; DOGS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYSACCHARIDES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTINS; SIALIC ACIDS;

ADENOVIRIDAE; CANINE ADENOVIRUS; HUMAN ADENOVIRUS TYPE 2; MIRIDAE; MUS;

EID: 84863226712     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cws073     Document Type: Article

References (28)

1. Angata T, Varki A. 2002. Chemical diversity in the sialic acids and related alpha-keto acids: An evolutionary perspective. Chem Rev. 102:439-469. (Pubitemid 35381636)
2. Attrill H, Imamura A, Sharma RS, Kiso M, Crocker PR, van Aalten DM. 2006. Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b. J Biol Chem. 281:32774-32783. (Pubitemid 46036833)
3. Attrill H, Takazawa H, Witt S, Kelm S, Isecke R, Brossmer R, Ando T, Ishida H, Kiso M, Crocker PR, et al. 2006. The structure of siglec-7 in complex with sialosides: Leads for rational structure-based inhibitor design. Biochem J. 397:271-278. (Pubitemid 44076896)
4. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE. 2000. The Protein Data Bank. Nucleic Acids Res. 28:235-242. (Pubitemid 30047768)
5. Blixt O, Head S, Mondala T, Scanlan C, Huflejt ME, Alvarez R, Bryan MC, Fazio F, Calarese D, Stevens J, et al. 2004. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc Natl Acad Sci USA. 101:17033-17038. (Pubitemid 39627769)
6. Bochner BS, Alvarez RA, Mehta P, Bovin NV, Blixt O, White JR, Schnaar RL. 2005. Glycan array screening reveals a candidate ligand for Siglec-8. J Biol Chem. 280:4307-4312. (Pubitemid 40288598)
7. Cock PJ, Antao T, Chang JT, Chapman BA, Cox CJ, Dalke A, Friedberg I, Hamelryck T, Kauff F, Wilczynski B, et al. 2009. Biopython: Freely available Python tools for computational molecular biology and bioinformatics. Bioinformatics. 25:1422-1423.
8. Crocker PR, Paulson JC, Varki A. 2007. Siglecs and their roles in the immune system. Nat Rev Immunol. 7:255-266. (Pubitemid 46480955)
9. DeMarco ML, Woods RJ. 2008. Structural glycobiology: A game of snakes and ladders. Glycobiology. 18:426-440. (Pubitemid 351753546)
10. Evers A, Gohlke H, Klebe G. 2003. Ligand-supported homology modelling of protein binding-sites using knowledge-based potentials. J Mol Biol. 334: 327-345. (Pubitemid 37361090)
11. Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O. 1997. Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase. J Biol Chem. 272:32321-32328. (Pubitemid 28011913)
12. Kumlin U, Olofsson S, Dimock K, Arnberg N. 2008. Sialic acid tissue distribution and influenza virus tropism. Influenza Other Respi Viruses. 2:147-154.
13. Labute P, Williams C, Feher M, Sourial E, Schmidt JM. 2001. Flexible alignment of small molecules. J Med Chem. 44:1483-1490. (Pubitemid 32852192)
14. Lutteke T, Bohne-Lang A, Loss A, Goetz T, Frank M, von der Lieth CW. 2006. GLYCOSCIENCES.de: An Internet portal to support glycomics and glycobiology research. Glycobiology. 16:71R-81R.
15. Lutteke T, von der Lieth CW. 2009. Data mining the PDB for glyco-related data. Methods Mol Biol. 534:293-310.
16. Nycholat CM, McBride R, Ekiert DC, Xu R, Rangarajan J, Peng W, Razi N, Gilbert M, Wakarchuk WW, Wilson IA, et al. 2012. Recognition of sialylated poly-LacNAc on N- and O-linked glycans by human and avian influenza Avirus hemagglutinins. Angew Chem Int Ed Engl. 51:4860-4863.
17. O'Reilly MK, Paulson JC. 2009. Siglecs as targets for therapy in immune-cell-mediated disease. Trends Pharmacol Sci. 30:240-248.
18. Rost B. 1999. Twilight zone of protein sequence alignments. Protein Eng. 12: 85-94. (Pubitemid 29103686)
19. Sawada T, Hashimoto T, Nakano H, Shigematsu M, Ishida H, Kiso M. 2006. Conformational study of OE±-N-acetyl-D-neuraminic acid by density functional theory. J Carbohyd Chem. 25:387-405. (Pubitemid 44114984)
20. Seiradake E, Henaff D, Wodrich H, Billet O, Perreau M, Hippert C, Mennechet F, Schoehn G, Lortat-Jacob H, Dreja H, et al. 2009. The cell adhesion molecule "CAR" and sialic acid on human erythrocytes influence adenovirus in vivo biodistribution. PLoS Pathog. 5:e1000277.
21. Siebert HC, Reuter G, Schauer R, von der Lieth CW, Dabrowski J. 1992. Solution conformations of GM3 gangliosides containing different sialic acid residues as revealed by NOE-based distance mapping, molecular mechanics, and molecular dynamics calculations. Biochemistry. 31:6962-6971.
22. Tateno H, Crocker PR, Paulson JC. 2005. Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6′-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology. 15:1125-1135. (Pubitemid 41662639)
23. Tateno H, Ohnishi K, Yabe R, Hayatsu N, Sato T, Takeya M, Narimatsu H, Hirabayashi J. 2010. Dual specificity of Langerin to sulfated and mannosylated glycans via a single C-type carbohydrate recognition domain. J Biol Chem. 285:6390-6400.
24. Varki A. 2009. Essentials of Glycobiology. 2nd ed. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press.
25. Xu R, McBride R, Nycholat CM, Paulson JC, Wilson IA. 2012. Structural characterization of the hemagglutinin receptor specificity from the 2009 H1N1 influenza pandemic. J Virol. 86:982-990.
26. Ye Y, Godzik A. 2003. Flexible structure alignment by chaining aligned fragment pairs allowing twists. Bioinformatics. 19 (Suppl 2):ii246-ii255. (Pubitemid 41296662)
27. Zaccai NR, May AP, Robinson RC, Burtnick LD, Crocker PR, Brossmer R, Kelm S, Jones EY. 2007. Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin. J Mol Biol. 365:1469-1479. (Pubitemid 46061426)
28. Zhuravleva MA, Trandem K, Sun PD. 2008. Structural implications of Siglec-5-mediated sialoglycan recognition. J Mol Biol. 375:437-447. (Pubitemid 350192476)