Histology of microvascular aging of human skin

Textbook of Aging Skin

Volumn , Issue , 2010, Pages 13-18

  Helmbold, Peter ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84863226047     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-540-89656-2_2     Document Type: Chapter

References (34)

1. Helmbold P, Lautenschlager C, Marsch W, et al. Detection of a physiological juvenile phase and the central role of pericytes in human dermal microvascular aging. J Invest Dermatol. 2006;126:1419-1421.
2. Helmbold P, Wohlrab J, Marsch WC, et al. Human dermal pericytes express 3G5 ganglioside-a new approach for microvessel histology in the skin. J Cutan Pathol. 2001;28:206-210.
3. Helmbold P, Fiedler E, Fischer M, et al. Hyperplasia of dermal microvascular pericytes in scleroderma. J Cutan Pathol. 2004;31: 431-440.
4. Helmbold P. Methodische Grundlagen zur Erforschung von Perizyten der Haut. In: Medizinische Fakultät. Halle (Saale): Martin-Luther- Universität Halle-Wittenberg. 2002.
5. Braverman IM. Elastic fiber and microvascular abnormalities in aging skin. Clin Geriatr Med. 1989;5:69-90.
6. Korkushko OV, Sarkisov KG. Age-specific characteristics of microcirculation in middle-and old age. Kardiologiia. 1976;16:19-25.
7. Herrick AL, Moore T, Hollis S, et al. The influence of age on nailfold capillary dimensions in childhood. J Rheumatol. 2000;27:797-800.
8. Leung WC, Harvey I. Is skin ageing in the elderly caused by sun exposure or smoking? Br J Dermatol. 2002;147:1187-1191.
9. Chung JH, Yano K, Lee MK, et al. Differential effects of photoaging vs intrinsic aging on the vascularization of human skin. Arch Dermatol. 2002;138:1437-1442.
10. Braverman IM. Ultrastructure and organization of the cutaneous microvasculature in normal and pathologic states. J Invest Dermatol. 1989;93:2S-9S.
11. Dehouck MP, Vigne P, Torpier G, et al. Endothelin-1 as a mediator of endothelial cell-pericyte interactions in bovine brain capillaries. J Cereb Blood Flow Metab. 1997;17:464-469.
12. Takagi H, King GL, Robinson GS, et al. Adenosine mediates hypoxic induction of vascular endothelial growth factor in retinal pericytes and endothelial cells. Invest Ophthalmol Vis Sci. 1996;37:2165-2176.
13. Kim Y, Imdad RY, Stephenson AH, et al. Vascular endothelial growth factor mRNA in pericytes is upregulated by phorbol myristate acetate. Hypertension. 1998;31:511-515.
14. Hirschi KK, D'Amore PA. Pericytes in the microvasculature. Cardiovasc Res. 1996;32:687-698.
15. Lindahl P, Johansson BR, Leveen P, et al. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997;277: 242-245.
16. Hirschi KK, D'Amore PA. Control of angiogenesis by the pericyte: Molecular mechanisms and significance. Exs. 1997;79:419-428.
17. de Oliveira F. Pericytes in diabetic retinopathy. Br J Ophthalmol. 1966;50:134-143.
18. Braverman IM, Sibley J, Keh A. Ultrastructural analysis of the endothelial-pericyte relationship in diabetic cutaneous vessels. J Invest Dermatol. 1990;95:147-153.
19. Wallow IH, Bindley CD, Reboussin DM, et al. Systemic hypertension produces pericyte changes in retinal capillaries. Invest Ophthalmol Vis Sci. 1993;34:420-430.
20. Schlingemann RO, Rietveld FJ, Kwaspen F, et al. Differential expression of markers for endothelial cells, pericytes, and basal lamina in the microvasculature of tumors and granulation tissue. Am J Pathol. 1991;138:1335-1347.
21. Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development. 1998;125:1591-1598.
22. Helmbold P, Fiedler E, Fischer M, et al. Hyperplasia of dermal microvascular pericytes in scleroderma. J Cutan Pathol.2004;31: 431-440.
23. Laaff H, Vandscheidt W, Weiss JM, et al. Immunohistochemical investigation of pericytes in chronic venous insufficiency. Vasa. 1991;20:323-328.
24. Lugassy C, Eyden BP, Christensen L, et al. Angio-tumoral complex in human malignant melanoma characterised by free laminin: Ultrastructural and immunohistochemical observations. J Submicrosc Cytol Pathol. 1997;29:19-28.
25. Tsukamoto H, Mishima Y, Hayashibe K, et al. Alpha-smooth muscle actin expression in tumor and stromal cells of benign and malignant human pigment cell tumors. J Invest Dermatol. 1992;98:116-120.
26. Sundberg C, Ivarsson M, Gerdin B, et al. Pericytes as collagenproducing cells in excessive dermal scarring. Lab Invest. 1996;74: 452-466.
27. Braverman IM, Sibley J. Ultrastructural and three-dimensional analysis of the contractile cells of the cutaneous microvasculature. J Invest Dermatol. 1990;95:90-96.
28. Gendron RL. A plasticity for blood vessel remodeling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Surv Ophthalmol. 1999;44:184-185.
29. Schönfelder U, Hofer A, Paul M, et al. In situ observation of living pericytes in rat retinal capillaries. Microvasc Res. 1998;56:22-29.
30. Erber R, Thurnher A, Katsen AD, et al. Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. FASEB J. 2004;18:338-340, Epub 2003 Dec;2004.
31. Sato Y, Rifkin DB. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture. J Cell Biol. 1989;109:309-315.
32. Antonelli-Orlidge A, Saunders KB, Smith SR, et al. An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. Proc Natl Acad Sci USA. 1989;86:4544-4548.
33. Massague J, Blain SW, Lo RS. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell. 2000;103:295-309.
34. Papetti M, Herman IM. Mechanisms of normal and tumor-derived angiogenesis. Am J Physiol Cell Physiol. 2002;282:947-970.