Reviewing the evidence for using continuous subcutaneous metoclopramide and ondansetron to treat nausea & vomiting during pregnancy

Managed Care

Volumn 21, Issue 5, 2012, Pages 44-47

  Reichmann, James P ^a   Kirkbride, Michael S ^a  

^a NONE   (United States)

Author keywords

Hyperemesis gravidarum; Metoclopramide (Reglan); Nausea and vomiting of pregnancy; Ondansetron (Zofran); Reglan pump; Zofran

Indexed keywords

ANTIEMETIC AGENT; METOCLOPRAMIDE; ONDANSETRON;

EVIDENCE BASED MEDICINE; FEMALE; HUMAN; NAUSEA; PREGNANCY; PREGNANCY COMPLICATION; REVIEW; SUBCUTANEOUS DRUG ADMINISTRATION; VOMITING;

ANTIEMETICS; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; INFUSIONS, SUBCUTANEOUS; METOCLOPRAMIDE; NAUSEA; ONDANSETRON; PREGNANCY; PREGNANCY COMPLICATIONS; VOMITING;

EID: 84863224522     PISSN: 10623388     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Review

References (20)

1. ACOG Committee on Ethics. ACOG Committee Opinion No. 352: Innovative practice: ethical guidelines. Obstet Gynecol. 2006; 108:1589-95.
2. Als-Nielsen B, Chen W, Gluud C, Kjaergard LL. Association of funding and conclusions in randomized drug trials: a reflection of treatment effect or adverse events? JAMA. 2003; 290(7):921-8.
3. Bekelman JE, Li Y, Gross CP. Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA. 2003; 289: 454-65.
4. Buchkowsky SS, Jewesson PJ. Industry sponsorship and authorship over 20 years. Ann Pharmacother. 2004; 38(4):579-585.
5. Buttino L, Gambon C. Home subcutaneous metoclopromide therapy for hyperemesis gravidarum. Prim Care Update Ob Gyns. 1998; 5(4):189.
6. Buttino L Jr., Coleman SK, Bergauer NK, Gambon C, Stanziano GJ. Home subcutaneous metoclopromide therapy for hyperemisis gravidarum. J Perinatol. 2000; 20(6):359-62.
7. Buttino L Jr., Gambon C, Coleman S. Home subcutaneous metoclopromide therapy for hyperemesis gravidarum. In: Koren G, Bishai R, editors. Nausea and vomiting of pregnancy: state of the art 2000. First International Conference on Nausea and Vomiting of Pregnancy. Toronto: Motherisk; 2000 P 84-9.
8. Chaudry S, Schroter S, Smith R, et al. Does declaration of competing interests affect readers' perceptions? A trial. BMJ. 2002:325:1391-2.
9. Dietz HP. Bias in research and conflict of interest: Why should we care? Int Urogynecol J Pelvic Floor Dysfunct. 2007; 18(3):241-3.
10. Goetzsehe P. Research integrity and pharmaceutical industry sponsorship. Med J Aust. 2005. 182(11):549.
11. Kassirer J. Physicians on the take. Med-GenMed. 2006; 8(1):74.
12. Klauser CK, Fox NS, Istwan N, Rhea D, Rebarber A, Desch C, Palmer B, Saltzman D. Treatment of severe nausea and vomiting of pregnancy with subcutaneous medications. Am J Perinatol. 2011 Oct; 28(9):715-22.
13. Lombardi DG, Istwan NB, Rhea DJ, O'Brien JM. Measuring outpatient outcomes of emesis and nausea management in pregnant women. Manag Care. 2004; 13(11):48-51.
14. McHenry L. Of sophists and spin-doctors: Industry-sponsored ghostwriting and the crisis of academic medicine. 2010; In: Psychopharmacology Today: Some Issues (A.R. Singh and S.A. Singh, eds.), MSM, 8, Jan-Dec 2010, p129-145.
15. Neaf RW III, Chauhan SP, Roach H, Roberts WE, Travis KH, Morrison JC. Treatment for hyperemesis gravidarum in the home: an alternative to hospitalization. J Pernatol. 1995; 15(4):289-92.
16. Reichmann JP, Kirkbride MS. Nausea and vomiting of pregnancy-cost effective pharmacologic treatments. Manag Care. 2008 Dec; 17(12):41-45.
17. Silverman GK, Loewenstein GF, Anderson BL, Ubel PA, Zinberg S, Schulkin J. Failure to discount for conflict of interest when evaluating medical literature: a trial of physicians. J Med Ethics. 2010; 36:265-270.
18. Sullivan CA, Johnson CA, Martin RN, Stewart DK, Morrison JC. A pilot study of ondansetron for hyperemesis gravidarum. Am J Obstet Gynecol. 1996; 174:1565-8.
19. "Trimethobenzamide Hydrochloride Suppositories; Withdrawal of Approval." Federal Register 72 (April 9, 2007). http//www.gpoaccess.gov/fr/index (accessed on April 13, 2011).
20. WellCare Health Plans, Inc. Coverage Guideline, Treatment of Nausea and Vomiting (Hyperemesis Gravidarum) during Pregnancy with Subcutaneous Misroinfusion Pump, Guideline Number: HS-016, Original effective date: 4/3/2008; Revision Date: 6/5/2009. Available at: http:www.wellcare.com/WCAssets/corporate/assets/HS016_Treatment_of_%20Nausea_and_Vomiting_in_Pregnancy_with_Subcutaneous_Pump.pdf. Retrieved October 27, 2010.