Treatment of severe nausea and vomiting of pregnancy with subcutaneous medications

American Journal of Perinatology

Volumn 28, Issue 9, 2011, Pages 715-721

  Klauser, Chad K ^a,b   Fox, Nathan S ^a,b   Istwan, Niki ^c   Rhea, Debbie ^c   Rebarber, Andrei ^a,b   Desch, Cheryl ^c   Palmer, Beverly ^c   Saltzman, Daniel ^a,b  

^a Maternal Fetal Medicine Associates   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c Alere Women's and Children's Health   (United States)

Author keywords

nausea and vomiting of pregnancy; NVP; subcutaneous metoclopramide; subcutaneous ondansetron

Indexed keywords

METOCLOPRAMIDE; ONDANSETRON;

ADULT; ARTICLE; CLINICAL EXAMINATION; COMPARATIVE STUDY; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG DOSE INCREASE; DRUG DOSE TITRATION; FEMALE; HOSPITALIZATION; HUMAN; INFUSION PUMP; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; NAUSEA AND VOMITING; NURSING; OUTPATIENT CARE; PHYSICIAN; PREGNANCY DISORDER; PRIORITY JOURNAL; SYMPTOM; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADOLESCENT; ADULT; ANTIEMETICS; FEMALE; HOME INFUSION THERAPY; HUMANS; INFUSIONS, SUBCUTANEOUS; METOCLOPRAMIDE; MIDDLE AGED; NAUSEA; ONDANSETRON; PREGNANCY; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; VOMITING; YOUNG ADULT;

EID: 80052966098     PISSN: 07351631     EISSN: 10988785     Source Type: Journal    
DOI: 10.1055/s-0031-1280594     Document Type: Article

References (21)

1. Jueckstock J K., Kaestner R, Mylonas I. Managing hyperemesis gravidarum: a multimodal challenge. BMC Medicine 2010;8:46. Available at: http://www.biomedcentral.com/1741-7015/8/46 Accessed November 24, 2010
2. Miller F. Nausea and vomiting in pregnancy: the problem of perceptionis it really a disease? Am J Obstet Gynecol 2002 186 5, Suppl Understanding S182-S183 (Pubitemid 34533871)
3. Eliakim R, Abulafia O, Sherer D M. Hyperemesis gravidarum: a current review. Am J Perinatol 2000 17 207-218
4. Goodwin T M. Hyperemesis gravidarum. Obstet Gynecol Clin North Am 2008 35 401-417 viii
5. Attard C L., Kohli M A., Coleman S et al. The burden of illness of severe nausea and vomiting of pregnancy in the United States. Am J Obstet Gynecol 2002 186 5, Suppl Understanding S220-S227 (Pubitemid 34533878)
6. Lacasse A, Rey E, Ferreira E, Morin C, Brard A. Nausea and vomiting of pregnancy: what about quality of life? BJOG 2008 115 1484-1493
7. Koren G, Boskovic R, Hard M, Maltepe C, Navioz Y, Einarson A. Motherisk-PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancy. Am J Obstet Gynecol 2002 186 5, Suppl Understanding S228-S231 (Pubitemid 34533879)
8. Niebyl J R. Clinical practice. Nausea and vomiting in pregnancy. N Engl J Med 2010 363 1544-1550
9. American College of Obstetrics and Gynecology. ACOG (American College of Obstetrics and Gynecology) Practice Bulletin: nausea and vomiting of pregnancy. Obstet Gynecol 2004 103 803-814
10. Naef R W. III, Chauhan S P., Roach H, Roberts W E., Travis K H., Morrison J C. Treatment for hyperemesis gravidarum in the home: an alternative to hospitalization. J Perinatol 1995 15 289-292
11. Buttino L Jr, Coleman S K., Bergauer N K., Gambon C, Stanziano G J. Home subcutaneous metoclopramide therapy for hyperemesis gravidarum. J Perinatol 2000 20 359-362
12. Lombardi D G., Istwan N B., Rhea D J., O'Brien J M., Barton J R. Measuring outpatient outcomes of emesis and nausea management in pregnant women. Manag Care 2004 13 48-52
13. Drugs.com. Ondansetron side effects. Available at: http://www.drugs.com/ sfx/ondansetron-side-effects.html Accessed May 23, 2011
14. Matok I, Gorodischer R, Koren G, Sheiner E, Wiznitzer A, Levy A. The safety of metoclopramide use in the first trimester of pregnancy. N Engl J Med 2009 360 2528-2535
15. Berkovitch M, Mazzota P, Greenberg R et al. Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study. Am J Perinatol 2002 19 311-316
16. Sørensen H T., Nielsen G L., Christensen K, Tage-Jensen U, Ekbom A, Baron J. Euromap Study Group. Birth outcome following maternal use of metoclopramide. The Euromap study group. Br J Clin Pharmacol 2000 49 264-268 (Pubitemid 30150988)
17. Tan P C., Khine P P., Vallikkannu N, Omar S Z. Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. Obstet Gynecol 2010 115 975-981
18. Einarson A, Maltepe C, Navioz Y, Kennedy D, Tan M P., Koren G. The safety of ondansetron for nausea and vomiting of pregnancy: a prospective comparative study. BJOG 2004 111 940-943 (Pubitemid 39223043)
19. Matthews A, Dowswell T, Haas D M., Doyle M, O'Mathna D P. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2010 CD007575
20. Wennberg D E., Marr A, Lang L, O'Malley S, Bennett G. A randomized trial of a telephone care-management strategy. N Engl J Med 2010 363 1245-1255
21. Altavela J L., Jones M K., Ritter M. A prospective trial of a clinical pharmacy intervention in a primary care practice in a capitated payment system. J Manag Care Pharm 2008 14 831-843