Characterization and crystal structure of the thermophilic ROK hexokinase from Thermus thermophilus

Journal of Bioscience and Bioengineering

Volumn 114, Issue 2, 2012, Pages 150-154

  Nakamura, Tsutomu ^a   Kashima, Yasuhiro ^b   Mine, Shouhei ^a   Oku, Takashi ^b   Uegaki, Koichi ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b Thermostable Enzyme Laboratory Co Ltd   (Japan)

Author keywords

Crystal structure; Glucokinase; Hexokinase; ROK family; Thermus thermophilus

Indexed keywords

ACCESSIBLE SURFACE AREAS; BOUND ZINC; CIRCULAR DICHROISM MEASUREMENTS; CONSENSUS SEQUENCE; ENZYMATIC ACTIVITIES; GLUCOKINASE; HEXOKINASES; HOMOTETRAMERS; LARGE DOMAIN; OPEN READING FRAME; POLYPEPTIDE STRUCTURES; ROK FAMILY; SUGAR KINASE; TETRAMERIC STRUCTURES; THERMOPHILUS; THERMUS THERMOPHILUS; X-RAY ABSORPTION FINE STRUCTURE SPECTRUM; ZINC FINGER;

AMINO ACIDS; CRYSTAL STRUCTURE; GLUCOSE; ZINC;

ENZYMES;

DIMER; FRUCTOSE; GALACTOSE; GLUCOSE; HEXOKINASE; MANNOSE; PHOSPHOTRANSFERASE; PROTEIN ROK; REPRESSOR PROTEIN; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; HYPERTHERMOPHILIC BACTERIUM; NONHUMAN; OPEN READING FRAME; PROTEIN DOMAIN; SEQUENCE ANALYSIS; THERMUS THERMOPHILUS; X RAY ABSORPTION SPECTROSCOPY; ZINC FINGER MOTIF;

AMINO ACID SEQUENCE; CONSENSUS SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; FRUCTOSE; GALACTOSE; GLUCOKINASE; GLUCOSE; HEXOKINASE; MANNOSE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, QUATERNARY; SUBSTRATE SPECIFICITY; THERMUS THERMOPHILUS; ZINC;

BACTERIA (MICROORGANISMS); THERMUS THERMOPHILUS;

EID: 84863203543     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2012.03.018     Document Type: Article

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