Discriminating astragali radix from its adulterants using HPLC coupled with chemometric clustering techniques

Journal of Food and Drug Analysis

Volumn 19, Issue 4, 2011, Pages

  Dong, Wei Wei ^a,b,c   Au, Dawn ^d   Cao, Xin Wei ^c   Li, Xiao Bo ^a   Yang, Da Jian ^c,d  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Shenzhen Virtual University Park Postdoc Station ^*  (China)

^c State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

^d HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Astragali radix; Hierarchical cluster analysis; HPLC; Isoflavonoids; Principle component analysis

Indexed keywords

CALYCOSIN; CALYCOSIN 7 O DEXTRO GLUCOPYRANOSIDE; FORMONONETIN; ISOFLAVONOID; ONONIN; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; ASTRAGALI RADIX; ASTRAGALUS CHRYSOPTERUS; ASTRAGALUS ERNESTII; ASTRAGALUS MEMBRANACEUS; ASTRAGALUS PLANT; CLUSTER ANALYSIS; CONTROLLED STUDY; DRUG ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRINCIPAL COMPONENT ANALYSIS;

EID: 84863173689     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. The State Pharmacopoeia Commission of P. R. China. 2010. Pharmacopoeia of the People's Republic of China. p 285. China Medicine Science and Technology Press of China. Beijing. China.
2. Sinclair, S. 1998. Chinese herbs: a clinical review of Astragalus, Ligusticum, and Schizandrae. Altern. Med. Rev. 3: 338-344. (Pubitemid 128709611)
3. Gui, S. Y., Wei, W., Wang, H., Wu, L., Sun, W. Y., Chen, W. B. and Wu, C. Y. 2006. Effects and mechanisms of crude astragalosides fraction on liver fibrosis in rats. J. Ethnopharmacol. 103: 154-159. (Pubitemid 41796911)
4. Liu, C. Y., Gu, Z. L., Zhou, W. X. and Guo, C. Y. 2005. Effect of Astragalus complanatus flavonoid on anti-liver fibrosis in rats. World J. Gastroenterol. 11: 5782-5786.
5. Li, J. X., Xue, B., Chai, Q., Liu, Z. X., Zhao, A. P. and Chen, L. B. 2005. Antihypertensive effect of total flavonoid fraction of Astragalus complanatus in hypertensive rats. Chin. J. Physiol. 48: 101-106. (Pubitemid 40867528)
6. Janick, J., Whipkey, A., Eds. 2002. Trends in New Crops and New Uses. p. 491. ASHS Press. Alexandria.
7. Lu, K. T., Lee, H. C., Liu, F. S., Lo, C. F. and Lin, J. H., 2009. Discriminating Astragali Radix from Hedysarum Radix in Chinese Medicine Preparations Using Nested PCR and DNA Sequencing Methods. J. Food Drug Anal. 17: 380-385.
8. Wu, S. Z. and He, Z. Q. 1992. The pharmacological study of Astragalus roots. Pharm. Clin. Chin. Mater. Med. 8: 24-27.
9. Wu, T., Bligh, S. W. A., Gu, L. H., Wang, Z. T., Liu, H. P., Cheng, X. M., Chris, J. B. W. and Hu, B. H. 2005. Simultaneous determination of six isoflavonoids in commercial Radix Astragali by HPLC-UV. Fitoterapia 76: 157-165. (Pubitemid 40326961)
10. Wang, D., Song, Y., Li, S. L., Bian, Y. Y., Guan, J. and Li, P. 2006. Simultaneous analysis of seven astragalosides in Radix Astragali and related preparations by liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry. J. Sep. Sci. 29: 2012-2022. (Pubitemid 44355483)
11. Qi, L. W, Yu, Q. T., Li, S. L., Wang, Y X., Sheng, L. H. and Yi, L. 2006. Quality evaluation of Radix Astragali through a simultaneous determination of six major active isoflavonoids and four main saponins by high-performance liquid chromatography coupled with diode array and evaporative light scattering detectors. J. Chromatorg. A 1134: 162-169. (Pubitemid 44740252)
12. Ding, Y., Xiang, L. Y., Zhang, T., Ji, S. and Xu, L. Y. 2010. Chemical fingerprint analysis of Gardenia jasminoides fruit by high-performance liquid chromatography. J. Food Drug Anal. 18: 180-190.
13. Qiao, C. F., He, Z. D., Han, Q. B., Xu, H. X., Jiang, R. W., Li, S. L., Zhang, Y. B., But, P. P. H. and Shaw, P. C. 2007. The use of lobetyolin and HPLC-UV fingerprints for quality assessment of Radix Codonopsis. J. Food Drug Anal. 15: 258-264.
14. Jiang, Y., Li, S. P., Wang, Y. T., Chen, X. J. and Tu, P. F. 2009. Differentiation of herba cistanches by fingerprint with high-performance liquid chromatography-diode array detection-mass spectrometry. J. Chromatorg. A 1216: 2156-2162.
15. Tong, L., Wang, Y. Z., Xiong, J. F., Cui, Y., Zhou, Y. G. and Yi, L. C. 2008. Selection and fingerprints of the control substances for plant drug Eucommia ulmodies Oliver by HPLC and LC-MS. Talanta 76: 80-84.