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Volumn 18, Issue 4, 2012, Pages 1028-1038

New gene-immunotherapy combining TRAIL-lymphocytes and EpCAMxCD3 bispecific antibody for tumor targeting

Author keywords

[No Author keywords available]

Indexed keywords

BISPECIFIC ANTIBODY; CHEMOKINE; EPITHELIAL CELL ADHESION MOLECULE;

EID: 84863132749     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-2767     Document Type: Article
Times cited : (19)

References (47)
  • 4
    • 49049086338 scopus 로고    scopus 로고
    • Ligand-based targeting of apoptosis in cancer: The potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
    • Ashkenazi A, Holland P, Eckhardt SG. Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J Clin Oncol 2008;26:3621-30.
    • (2008) J Clin Oncol , vol.26 , pp. 3621-3630
    • Ashkenazi, A.1    Holland, P.2    Eckhardt, S.G.3
  • 7
    • 56249091888 scopus 로고    scopus 로고
    • Mesenchymal Stem Cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model
    • Mohr A, Lyons M, Deedigan L, Harte T, Shaw G, Howard L, et al. Mesenchymal Stem Cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model. J Cell Mol Med 2008;12:2628-43.
    • (2008) J Cell Mol Med , vol.12 , pp. 2628-2643
    • Mohr, A.1    Lyons, M.2    Deedigan, L.3    Harte, T.4    Shaw, G.5    Howard, L.6
  • 8
    • 77950433110 scopus 로고    scopus 로고
    • Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature
    • Lavazza C, Carlo-Stella C, Giacomini A, Cleris L, Righi M, Sia D, et al. Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature. Blood 2010;115:2231-40.
    • (2010) Blood , vol.115 , pp. 2231-2240
    • Lavazza, C.1    Carlo-Stella, C.2    Giacomini, A.3    Cleris, L.4    Righi, M.5    Sia, D.6
  • 9
    • 33646823935 scopus 로고    scopus 로고
    • In vitro enhanced cytotoxicity of tumor-infiltrating lymphocytes transfected with tumor necrosis factor-related apoptosis-inducing ligand and/or interleukin-2 gene in human renal cell carcinoma
    • DOI 10.1016/j.urology.2005.11.030, PII S0090429505016456
    • Tian JQ, Wang ZP, Rodriguez R, Fu JS, Lu JZ, Ma BL. In vitro enhanced cytotoxicity of tumor-infiltrating lymphocytes transfected with tumor necrosis factor-related apoptosis-inducing ligand and/or interleukin-2 gene in human renal cell carcinoma. Urology 2006;67:1093-8. (Pubitemid 43964821)
    • (2006) Urology , vol.67 , Issue.5 , pp. 1093-1098
    • Tian, J.-Q.1    Wang, Z.-P.2    Rodriguez, R.3    Fu, J.-S.4    Lu, J.-Z.5    Ma, B.-L.6
  • 11
    • 58849085569 scopus 로고    scopus 로고
    • BiTE: Teaching antibodies to engage T-cells for cancer therapy
    • Baeuerle PA, Kufer P, Bargou R. BiTE: Teaching antibodies to engage T-cells for cancer therapy. Curr Opin Mol Ther 2009;11:22-30.
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 22-30
    • Baeuerle, P.A.1    Kufer, P.2    Bargou, R.3
  • 12
    • 0035889129 scopus 로고    scopus 로고
    • Induction of a long-lasting antitumor immunity by a trifunctional bispecific antibody
    • Ruf P, Lindhofer H. Induction of a long-lasting antitumor immunity by a trifunctional bispecific antibody. Blood 2001;98:2526-34.
    • (2001) Blood , vol.98 , pp. 2526-2534
    • Ruf, P.1    Lindhofer, H.2
  • 13
    • 77954676136 scopus 로고    scopus 로고
    • The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial
    • Heiss MM, Murawa P, Koralewski P, Kutarska E, Kolesnik OO, Ivanchenko VV, et al. The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial. Int J Cancer 2010;127:2209-21.
    • (2010) Int J Cancer , vol.127 , pp. 2209-2221
    • Heiss, M.M.1    Murawa, P.2    Koralewski, P.3    Kutarska, E.4    Kolesnik, O.O.5    Ivanchenko, V.V.6
  • 14
    • 0037056226 scopus 로고    scopus 로고
    • Intraperitoneal bispecific antibody (HEA125XOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma
    • DOI 10.1002/ijc.10562
    • Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G. Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma. Int J Cancer 2002;101:183-9. (Pubitemid 34970911)
    • (2002) International Journal of Cancer , vol.101 , Issue.2 , pp. 183-189
    • Marme, A.1    Strauss, G.2    Bastert, G.3    Grischke, E.-M.4    Moldenhauer, G.5
  • 15
    • 77449145878 scopus 로고    scopus 로고
    • Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma
    • Salnikov AV, Groth A, Apel A, Kallifatidis G, Beckermann BM, Khamidjanov A, et al. Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma. J Cell Mol Med 2009;13:4023-33.
    • (2009) J Cell Mol Med , vol.13 , pp. 4023-4033
    • Salnikov, A.V.1    Groth, A.2    Apel, A.3    Kallifatidis, G.4    Beckermann, B.M.5    Khamidjanov, A.6
  • 16
    • 0023180716 scopus 로고
    • Immunohistochemical study of the expression of a M(r) 34,000 human epithelium-specific surface glycoprotein in normal and malignant tissues
    • Momburg F, Moldenhauer G, Hammerling GJ, Moller P. Immunohistochemical study of the expression of a Mr 34,000 human epithelium-specific surface glycoprotein in normal and malignant tissues. Cancer Res 1987;47:2883-91. (Pubitemid 17113431)
    • (1987) Cancer Research , vol.47 , Issue.11 , pp. 2883-2891
    • Momburg, F.1    Moldenhauer, G.2    Hammerling, G.J.3    Moller, P.4
  • 19
    • 0034627152 scopus 로고    scopus 로고
    • Ep-CAM overexpression in breast cancer as a predictor of survival
    • Gastl G, Spizzo G, Obrist P, Dunser M, Mikuz G. Ep-CAM overexpression in breast cancer as a predictor of survival. Lancet 2000;356:1981-2.
    • (2000) Lancet , vol.356 , pp. 1981-1982
    • Gastl, G.1    Spizzo, G.2    Obrist, P.3    Dunser, M.4    Mikuz, G.5
  • 22
    • 34047096557 scopus 로고    scopus 로고
    • Cancer stem cells: Models and concepts
    • DOI 10.1146/annurev.med.58.062105.204854
    • Dalerba P, Cho RW, Clarke MF. Cancer stem cells: models and concepts. Annu Rev Med 2007;58:267-84. (Pubitemid 46706514)
    • (2007) Annual Review of Medicine , vol.58 , pp. 267-284
    • Dalerba, P.1    Cho, R.W.2    Clarke, M.F.3
  • 24
    • 34548455927 scopus 로고    scopus 로고
    • Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer
    • DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
    • Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007;1:313-23. (Pubitemid 47355323)
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 25
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • DOI 10.1158/0008-5472.CAN-05-2018
    • Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005;65:10946-51. (Pubitemid 41713363)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 26
    • 67649637824 scopus 로고    scopus 로고
    • Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling
    • Kallifatidis G, Rausch V, Baumann B, Apel A, Beckermann BM, Groth A, et al. Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. Gut 2009;58:949-63.
    • (2009) Gut , vol.58 , pp. 949-963
    • Kallifatidis, G.1    Rausch, V.2    Baumann, B.3    Apel, A.4    Beckermann, B.M.5    Groth, A.6
  • 27
    • 0032925519 scopus 로고    scopus 로고
    • Without prior stimulation, tumor-associated lymphocytes from malignant effusions lyse autologous tumor cells in the presence of bispecific antibody HEA125xOKT3
    • Strauss G, Guckel B, Wallwiener D, Moldenhauer G. Without prior stimulation, tumor-associated lymphocytes from malignant effusions lyse autologous tumor cells in the presence of bispecific antibody HEA125xOKT3. Clin Cancer Res 1999;5:171-80. (Pubitemid 29045191)
    • (1999) Clinical Cancer Research , vol.5 , Issue.1 , pp. 171-180
    • Strauss, G.1    Guckel, B.2    Wallwiener, D.3    Moldenhauer, G.4
  • 28
    • 0031974417 scopus 로고    scopus 로고
    • TRAIL/Apo-2-ligand-induced apoptosis in human T cells
    • DOI 10.1002/(SICI)1521-4141(199801)28:01<143::AID-IMMU143>3.0.CO;2- 3
    • Jeremias I, Herr I, Boehler T, Debatin K-M. TRAIL/APO-2-ligand-induced apoptosis in human T cells. Eur J Immunol 1998;28:143-52. (Pubitemid 28048285)
    • (1998) European Journal of Immunology , vol.28 , Issue.1 , pp. 143-152
    • Jeremias, I.1    Herr, I.2    Boehler, T.3    Debatin, K.-M.4
  • 29
    • 78650901935 scopus 로고    scopus 로고
    • Sulforaphane increases drug-mediated cytotoxicity towards cancer stem-like cells of pancreas and prostate
    • Kallifatidis G, Labsch S, Rausch V, Mattern J, Gladkich J, Moldenhauer G, et al. Sulforaphane increases drug-mediated cytotoxicity towards cancer stem-like cells of pancreas and prostate. Mol Ther 2011;19:188-95.
    • (2011) Mol Ther , vol.19 , pp. 188-195
    • Kallifatidis, G.1    Labsch, S.2    Rausch, V.3    Mattern, J.4    Gladkich, J.5    Moldenhauer, G.6
  • 30
    • 40949088678 scopus 로고    scopus 로고
    • PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells
    • DOI 10.1158/0008-5472.CAN-07-5878
    • Li H, Chen X, Calhoun-Davis T, Claypool K, Tang DG. PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res 2008;68:1820-5. (Pubitemid 351416567)
    • (2008) Cancer Research , vol.68 , Issue.6 , pp. 1820-1825
    • Li, H.1    Chen, X.2    Calhoun-Davis, T.3    Claypool, K.4    Tang, D.G.5
  • 31
    • 0242684481 scopus 로고    scopus 로고
    • Efficient tumor cell lysis by autologous, tumor-resident T lymphocytes in primary ovarian cancer samples by an EP-CAM-/CD3-bispecific antibody
    • DOI 10.1002/ijc.11056
    • Wimberger P, Xiang W, Mayr D, Diebold J, Dreier T, Baeuerle PA, et al. Efficient tumor cell lysis by autologous, tumor-resident T lymphocytes in primary ovarian cancer samples by an EP-CAM-/CD3-bispecific antibody. Int J Cancer 2003;105:241-8. (Pubitemid 36505328)
    • (2003) International Journal of Cancer , vol.105 , Issue.2 , pp. 241-248
    • Wimberger, P.1    Xiang, W.2    Mayr, D.3    Diebold, J.4    Dreier, T.5    Baeuerle, P.A.6    Kimmig, R.7
  • 32
    • 0034812659 scopus 로고    scopus 로고
    • Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: Characterization of in vivo efficacy, pharmacokinetics, and safety
    • Kelley SK, Harris LA, Xie D, Deforge L, Totpal K, Bussiere J, et al. Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safety. J Pharmacol Exp Ther 2001;299:31-8. (Pubitemid 32905115)
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.299 , Issue.1 , pp. 31-38
    • Kelley, S.K.1    Harris, L.A.2    Xie, D.3    Deforge, L.4    Totpal, K.5    Bussiere, J.6    Fox, J.A.7
  • 33
    • 66249083525 scopus 로고    scopus 로고
    • Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer
    • Loebinger MR, Eddaoudi A, Davies D, Janes SM. Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer. Cancer Res 2009;69:4134-42.
    • (2009) Cancer Res , vol.69 , pp. 4134-4142
    • Loebinger, M.R.1    Eddaoudi, A.2    Davies, D.3    Janes, S.M.4
  • 34
    • 0033178740 scopus 로고    scopus 로고
    • Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing
    • Zeidler R, Reisbach G, Wollenberg B, Lang S, Chaubal S, Schmitt B, et al. Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing. J Immunol 1999;163:1246-52. (Pubitemid 29352740)
    • (1999) Journal of Immunology , vol.163 , Issue.3 , pp. 1246-1252
    • Zeidler, R.1    Reisbach, G.2    Wollenberg, B.3    Lang, S.4    Chaubal, S.5    Schmitt, B.6    Lindhofer, H.7
  • 36
    • 78149460436 scopus 로고    scopus 로고
    • Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells
    • Herrmann I, Baeuerle PA, Friedrich M, Murr A, Filusch S, Ruttinger D, et al. Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells. PLoS ONE 2010;5:e13474.
    • (2010) PLoS ONE , vol.5
    • Herrmann, I.1    Baeuerle, P.A.2    Friedrich, M.3    Murr, A.4    Filusch, S.5    Ruttinger, D.6
  • 37
    • 0041845009 scopus 로고    scopus 로고
    • Trail induces apoptosis and inflammatory gene expression in human endothelial cells
    • Li JH, Kirkiles-Smith NC, McNiff JM, Pober JS. TRAIL induces apoptosis and inflammatory gene expression in human endothelial cells. J Immunol 2003;171:1526-33. (Pubitemid 36900088)
    • (2003) Journal of Immunology , vol.171 , Issue.3 , pp. 1526-1533
    • Li, J.H.1    Kirkiles-Smith, N.C.2    McNiff, J.M.3    Pober, J.S.4
  • 38
    • 23844464209 scopus 로고    scopus 로고
    • TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2
    • DOI 10.1159/000086599
    • Alladina SJ, Song JH, Davidge ST, Hao C, Easton AS. TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2. J Vasc Res 2005;42:337-47. (Pubitemid 41160235)
    • (2005) Journal of Vascular Research , vol.42 , Issue.4 , pp. 337-347
    • Alladina, S.J.1    Song, J.H.2    Davidge, S.T.3    Hao, C.4    Easton, A.S.5
  • 40
    • 33747152779 scopus 로고    scopus 로고
    • Cytokines and chemokines as regulators of angiogenesis in health and disease
    • DOI 10.2174/138161206777947461
    • Benelli R, Lorusso G, Albini A, Noonan DM. Cytokines and chemokines as regulators of angiogenesis in health and disease. Curr Pharm Des 2006;12:3101-15. (Pubitemid 44227572)
    • (2006) Current Pharmaceutical Design , vol.12 , Issue.24 , pp. 3101-3115
    • Benelli, R.1    Lorusso, G.2    Albini, A.3    Noonan, D.M.4
  • 42
    • 34547469573 scopus 로고    scopus 로고
    • On the TRAIL to therapeutic intervention in liver disease
    • DOI 10.1002/hep.21740
    • Herr I, Schemmer P, Buchler MW. On the TRAIL to therapeutic intervention in liver disease. Hepatology 2007;46:266-74. (Pubitemid 47171943)
    • (2007) Hepatology , vol.46 , Issue.1 , pp. 266-274
    • Herr, I.1    Schemmer, P.2    Buchler, M.W.3
  • 43
    • 70249090374 scopus 로고    scopus 로고
    • Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
    • Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF, et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 2009;461:282-6.
    • (2009) Nature , vol.461 , pp. 282-286
    • Elliott, M.R.1    Chekeni, F.B.2    Trampont, P.C.3    Lazarowski, E.R.4    Kadl, A.5    Walk, S.F.6
  • 44
    • 0028685525 scopus 로고
    • Pancreatic pseudocysts, ascites, and fistulas
    • Yeo CJ. Pancreatic pseudocysts, ascites, and fistulas. Curr Opin Gen Surg 1994;173-8.
    • (1994) Curr Opin Gen Surg , pp. 173-178
    • Yeo, C.J.1
  • 47
    • 70449127230 scopus 로고    scopus 로고
    • Insertional transformation of hematopoietic cells by selfin-activating lentiviral and gammaretroviral vectors
    • Modlich U, Navarro S, Zychlinski D, Maetzig T, Knoess S, Brugman MH, et al. Insertional transformation of hematopoietic cells by selfin-activating lentiviral and gammaretroviral vectors. Mol Ther 2009;17:1919-28.
    • (2009) Mol Ther , vol.17 , pp. 1919-1928
    • Modlich, U.1    Navarro, S.2    Zychlinski, D.3    Maetzig, T.4    Knoess, S.5    Brugman, M.H.6


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