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Volumn 3, Issue 4, 2012, Pages 879-884

Silencing Notch-1 induces apoptosis and increases the chemosensitivity of prostate cancer cells to docetaxel through Bcl-2 and Bax

Author keywords

Apoptosis; Bax; Bcl 2; Notch signaling; Prostate cancer; Small interfering RNA

Indexed keywords

DOCETAXEL; NOTCH1 RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA;

EID: 84863131344     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.572     Document Type: Article
Times cited : (80)

References (34)
  • 1
    • 0003432464 scopus 로고    scopus 로고
    • American Cancer Society, Cancer Facts and Figures 2011, Atlanta
    • American Cancer Society: Cancer Facts and Figures 2011. American Cancer Society, Atlanta, 2011.
    • (2011) American Cancer Society
  • 2
    • 0032497522 scopus 로고    scopus 로고
    • Bilateral orchiectomy with or without flutamide for metastatic prostate cancer
    • Eisenberger MA, Blumenstein BA, Crawford ED, et al: Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. N Engl J Med 339: 1036-1042, 1998.
    • (1998) N Engl J Med , vol.339 , pp. 1036-1042
    • Eisenberger, M.A.1    Blumenstein, B.A.2    Crawford, E.D.3
  • 3
    • 77649158894 scopus 로고    scopus 로고
    • NCCN clinical practice guidelines in oncology: Prostate cancer
    • Mohler J, Bahnson RR, Boston B, et al: NCCN clinical practice guidelines in oncology: prostate cancer. J Natl Compr Canc Netw 8: 162-200, 2010.
    • (2010) J Natl Compr Canc Netw , vol.8 , pp. 162-200
    • Mohler, J.1    Bahnson, R.R.2    Boston, B.3
  • 4
    • 78549257475 scopus 로고    scopus 로고
    • Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy
    • Ploussard G, Terry S, Maille P, et al: Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy. Cancer Res 70: 9253-9264, 2010.
    • (2010) Cancer Res , vol.70 , pp. 9253-9264
    • Ploussard, G.1    Terry, S.2    Maille, P.3
  • 5
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • Petrylak DP, Tangen CM, Hussain MHA, et al: Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. New Engl J Med 351: 1513-1520, 2004.
    • (2004) New Engl J Med , vol.351 , pp. 1513-1520
    • Petrylak, D.P.1    Tangen, C.M.2    Hussain, M.H.A.3
  • 6
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD and Lake RJ: Notch signaling: cell fate control and signal integration in development. Science 284: 770-776, 1999.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 7
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: Unfolding the activation mechanism
    • Kopan R and Ilagan MX: The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137: 216-233, 2009.
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 8
    • 33644752839 scopus 로고    scopus 로고
    • Notch signaling
    • Miele L: Notch signaling. Clin Cancer Res 12: 1074-1079, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 1074-1079
    • Miele, L.1
  • 10
    • 47849127390 scopus 로고    scopus 로고
    • The Notch pathway in prostate development and cancer
    • Leong KG and Gao WQ: The Notch pathway in prostate development and cancer. Differentiation 76: 699-716, 2008.
    • (2008) Differentiation , vol.76 , pp. 699-716
    • Leong, K.G.1    Gao, W.Q.2
  • 11
    • 55449084812 scopus 로고    scopus 로고
    • Notch Signaling: A potential therapeutic target in prostate cancer
    • Villaronga MA, Bevan CL and Belandia B: Notch Signaling: a potential therapeutic target in prostate cancer. Curr Cancer Drug Tar 8: 566-580, 2008.
    • (2008) Curr Cancer Drug Tar , vol.8 , pp. 566-580
    • Villaronga, M.A.1    Bevan, C.L.2    Belandia, B.3
  • 12
    • 0035476048 scopus 로고    scopus 로고
    • Dynamics of notch expression during murine prostate development and tumorigenesis
    • Shou JY, Ross S, Koeppen H, de Sauvage FJ and Gao WQ: Dynamics of notch expression during murine prostate development and tumorigenesis. Cancer Res 61: 7291-7297, 2001.
    • (2001) Cancer Res , vol.61 , pp. 7291-7297
    • Shou, J.Y.1    Ross, S.2    Koeppen, H.3    de Sauvage, F.J.4    Gao, W.Q.5
  • 14
    • 59449107891 scopus 로고    scopus 로고
    • Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator
    • Bin Hafeez B, Adhami VM, Asim M, et al: Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator. Clin Cancer Res 15: 452-459, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 452-459
    • Hafeez, B.B.1    Adhami, V.M.2    Asim, M.3
  • 15
    • 77749321234 scopus 로고    scopus 로고
    • Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappa B signaling pathways
    • Wang ZW, Li Y, Banerjee S, et al: Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappa B signaling pathways. J Cell Biochem 109: 726-736, 2010.
    • (2010) J Cell Biochem , vol.109 , pp. 726-736
    • Wang, Z.W.1    Li, Y.2    Banerjee, S.3
  • 16
    • 33947274103 scopus 로고    scopus 로고
    • Hedgehog pathway activity in the LADY prostate tumor model
    • Bushman W, Gipp J, Gu GY, Crylen C and Kasper S: Hedgehog pathway activity in the LADY prostate tumor model. Mol Cancer 6: 19, 2007.
    • (2007) Mol Cancer , vol.6 , pp. 19
    • Bushman, W.1    Gipp, J.2    Gu, G.Y.3    Crylen, C.4    Kasper, S.5
  • 17
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 18
    • 55249099408 scopus 로고    scopus 로고
    • Combination of vitamin E and selenium causes an induction of apoptosis of human prostate cancer cells by enhancing Bax/Bcl-2 ratio
    • Reagan-Shaw S, Nihal M, Ahsan H, Mukhtar H and Ahmad N: Combination of vitamin E and selenium causes an induction of apoptosis of human prostate cancer cells by enhancing Bax/Bcl-2 ratio. Prostate 68: 1624-1634, 2008.
    • (2008) Prostate , vol.68 , pp. 1624-1634
    • Reagan-Shaw, S.1    Nihal, M.2    Ahsan, H.3    Mukhtar, H.4    Ahmad, N.5
  • 19
    • 50849104230 scopus 로고    scopus 로고
    • Notch tumor suppressor function
    • Dotto GP: Notch tumor suppressor function. Oncogene 27: 5115-5123, 2008.
    • (2008) Oncogene , vol.27 , pp. 5115-5123
    • Dotto, G.P.1
  • 20
    • 70449732855 scopus 로고    scopus 로고
    • Expression of Notch1, Jagged1 and beta-catenin and their clinicopathological significance in hepatocellular carcinoma
    • Wang M, Xue L, Cao Q, et al: Expression of Notch1, Jagged1 and beta-catenin and their clinicopathological significance in hepatocellular carcinoma. Neoplasma 56: 533-541, 2009.
    • (2009) Neoplasma , vol.56 , pp. 533-541
    • Wang, M.1    Xue, L.2    Cao, Q.3
  • 21
    • 33845987566 scopus 로고    scopus 로고
    • Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells
    • Kunnimalaiyaan M, Vaccaro AM, Ndiaye MA and Chen H: Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells. J Biol Chem 281: 39819-39830, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 39819-39830
    • Kunnimalaiyaan, M.1    Vaccaro, A.M.2    Ndiaye, M.A.3    Chen, H.4
  • 22
    • 34249936877 scopus 로고    scopus 로고
    • Notch signaling inhibits growth of the human lung adenocarcinoma cell line A549
    • Zheng Q, Qin H, Zhang H, et al: Notch signaling inhibits growth of the human lung adenocarcinoma cell line A549. Oncol Rep 17: 847-852, 2007.
    • (2007) Oncol Rep , vol.17 , pp. 847-852
    • Zheng, Q.1    Qin, H.2    Zhang, H.3
  • 23
    • 10744223624 scopus 로고    scopus 로고
    • Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
    • Miyamoto Y, Maitra A, Ghosh B, et al: Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 3: 565-576, 2003.
    • (2003) Cancer Cell , vol.3 , pp. 565-576
    • Miyamoto, Y.1    Maitra, A.2    Ghosh, B.3
  • 25
    • 0034574386 scopus 로고    scopus 로고
    • Novel association of a diverse range of genes with renal cell carcinoma as identified by differential display
    • Rae FK, Stephenson SA, Nicol DL and Clements JA: Novel association of a diverse range of genes with renal cell carcinoma as identified by differential display. Int J Cancer 88: 726-732, 2000.
    • (2000) Int J Cancer , vol.88 , pp. 726-732
    • Rae, F.K.1    Stephenson, S.A.2    Nicol, D.L.3    Clements, J.A.4
  • 26
    • 20144387679 scopus 로고    scopus 로고
    • Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation
    • Purow BW, Haque RM, Noel MW, et al: Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Res 65: 2353-2363, 2005.
    • (2005) Cancer Res , vol.65 , pp. 2353-2363
    • Purow, B.W.1    Haque, R.M.2    Noel, M.W.3
  • 27
    • 27144504699 scopus 로고    scopus 로고
    • The Notch pathway in ovarian carcinomas and adenomas
    • Hopfer O, Zwahlen D, Fey MF and Aebi S: The Notch pathway in ovarian carcinomas and adenomas. Br J Cancer 93: 709-718, 2005.
    • (2005) Br J Cancer , vol.93 , pp. 709-718
    • Hopfer, O.1    Zwahlen, D.2    Fey, M.F.3    Aebi, S.4
  • 28
    • 24944506696 scopus 로고    scopus 로고
    • High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
    • Reedijk M, Odorcic S, Chang L, et al: High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 65: 8530-8537, 2005.
    • (2005) Cancer Res , vol.65 , pp. 8530-8537
    • Reedijk, M.1    Odorcic, S.2    Chang, L.3
  • 29
    • 77949457142 scopus 로고    scopus 로고
    • RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer
    • Zang SL, Chen F, Dai JJ, et al: RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer. Oncol Rep 23: 893-899, 2010.
    • (2010) Oncol Rep , vol.23 , pp. 893-899
    • Zang, S.L.1    Chen, F.2    Dai, J.J.3
  • 30
    • 41349095228 scopus 로고    scopus 로고
    • Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy
    • Nefedova Y, Sullivan DM, Bolick SC, Dalton WS and Gabrilovich DI: Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy. Blood 111: 2220-2229, 2008.
    • (2008) Blood , vol.111 , pp. 2220-2229
    • Nefedova, Y.1    Sullivan, D.M.2    Bolick, S.C.3    Dalton, W.S.4    Gabrilovich, D.I.5
  • 32
    • 67149138004 scopus 로고    scopus 로고
    • Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells
    • Rasul S, Balasubramanian R, Filipovic A, Slade MJ, Yague E and Coombes RC: Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells. Br J Cancer 100: 1879-1888, 2009.
    • (2009) Br J Cancer , vol.100 , pp. 1879-1888
    • Rasul, S.1    Balasubramanian, R.2    Filipovic, A.3    Slade, M.J.4    Yague, E.5    Coombes, R.C.6
  • 33
    • 1242272838 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells
    • Chun E and Lee KY: Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells. Biochem Biophys Res Commun 315: 771-779, 2004.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 771-779
    • Chun, E.1    Lee, K.Y.2
  • 34
    • 33750723137 scopus 로고    scopus 로고
    • Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy
    • Yoshino T, Shiina H, Urakami S, et al: Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy. Clin Cancer Res 12: 6116-6124, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 6116-6124
    • Yoshino, T.1    Shiina, H.2    Urakami, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.