Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities

Chemistry and Biodiversity

Volumn 9, Issue 2, 2012, Pages 428-440

  Zhang, Jie ^a   Huang, Yan ^a   Kikuchi, Takashi ^a   Tokuda, Harukuni ^b   Suzuki, Nobutaka ^b   Inafuku, Kei Ichiro ^c   Miura, Motofumi ^a   Motohashi, Shigeyasu ^a   Suzuki, Takashi ^a   Akihisa, Toshihiro ^a  

^a NIHON UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c Okinawa Hakko Kagaku Co Ltd   (Japan)

Author keywords

Anti tumor promoting activity; Cucurbitane triterpenoids; Cytotoxic activity; Inhibitors; Momordica charantia; Triterpenoids

Indexed keywords

3BETA HYDROXY 23 METHOXYCUCURBITA 5,24 DIEN 19 AL 7BETA YL BETA GLUCOPYRANOSIDE; 3BETA HYDROXY 25 OXO 27 NORCUCURBITA 5,23 DIEN 19 AL 7BETA YL BETA GLUCOPYRANOSIDE; 3BETA HYDROXY 7BETA,23 DIMETHOXYCUCURBITA 5,24 DIEN 19 AL; 3BETA HYDROXY25 METHOXYCUCURBITA 6,23 DIEN 19,5BETA OLIDE; 3BETA,25 DIHYDROXY 7B METHOXYCUCURBITA 5,23 DIEN 19 AL; 3BETA,25,26 TRIHYDROXYCUCURBITA 5,23 DIEN 19 AL 7BETA YL BETA GLUCOPYRANOSIDE; 3BETA,7BETA DIHYDROXY 25 METHOXYCUCURBITA 5,23 DIEN 19 AL; CUCURBITANE TRITERPENOID; KARAVILAGENIN D; MOMORDICOSIDE L; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; MOMORDICA CHARANTIA; MOUSE; NONHUMAN; PLANT LEAF;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTIGENS, VIRAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; GLYCOSIDES; HUMANS; MICE; MOLECULAR STRUCTURE; MOMORDICA CHARANTIA; PLANT LEAVES; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 84863118843     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.201100142     Document Type: Article

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