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Volumn 125, Issue 4, 2012, Pages 687-695

Gemifloxacin for the treatment of community-acquired pneumonia and acute exacerbation of chronic bronchitis: A meta-analysis of randomized controlled trials

Author keywords

Beta lactams; Gemifloxacin; Quinolones; Safety

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; BETA LACTAM ANTIBIOTIC; CEFTRIAXONE; CEFUROXIME; CLARITHROMYCIN; GEMIFLOXACIN; LEVOFLOXACIN; MACROLIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TROVAFLOXACIN;

EID: 84863118235     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.04.024     Document Type: Article
Times cited : (6)

References (54)
  • 1
    • 33847155159 scopus 로고    scopus 로고
    • Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
    • Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD, Dean NC, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007; 44 Suppl 2: s27-s72.
    • (2007) Clin Infect Dis , vol.44 , Issue.SUPPL. 2
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3    Bartlett, J.G.4    Campbell, G.D.5    Dean, N.C.6
  • 2
    • 54449093808 scopus 로고    scopus 로고
    • Role of gemifloxacin in community-acquired pneumonia
    • Tillotson GS. Role of gemifloxacin in community-acquired pneumonia. Expert Rev Anti Infect Ther 2008; 6: 40 5-418.
    • (2008) Expert Rev Anti Infect Ther , vol.6 , Issue.40 , pp. 5-418
    • Tillotson, G.S.1
  • 3
    • 31844435204 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Current burden and future projections
    • Lopez AD, Shibuya K, Rao C, Mathers CD, Hansell AL, Held LS, et al. Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J 2006; 27: 39 7-412.
    • (2006) Eur Respir J , vol.27 , Issue.39 , pp. 7-412
    • Lopez, A.D.1    Shibuya, K.2    Rao, C.3    Mathers, C.D.4    Hansell, A.L.5    Held, L.S.6
  • 4
    • 31544465514 scopus 로고    scopus 로고
    • International Primary Care Respiratory Group (IPCRG) Guidelines: Management of chronic obstructive pulmonary disease (COPD)
    • Bellamy D, Bouchard J, Henrichsen S, Johansson G, Langhammer A, Reid J, et al. International Primary Care Respiratory Group (IPCRG) Guidelines: management of chronic obstructive pulmonary disease (COPD). Prim Care Respir J 2006; 15: 4 8-57.
    • (2006) Prim Care Respir J , vol.15 , Issue.4 , pp. 8-57
    • Bellamy, D.1    Bouchard, J.2    Henrichsen, S.3    Johansson, G.4    Langhammer, A.5    Reid, J.6
  • 5
    • 18644375970 scopus 로고    scopus 로고
    • Guide to selection of fluoroquinolones in patients with lower respiratory tract infections
    • Shams WE, Evans ME. Guide to selection of fluoroquinolones in patients with lower respiratory tract infections. Drugs 2005; 65: 94 9-991.
    • (2005) Drugs , vol.65 , Issue.94 , pp. 9-991
    • Shams, W.E.1    Evans, M.E.2
  • 6
    • 4644359864 scopus 로고    scopus 로고
    • BSAC Respiratory Resistance Surveillance Programme (2002-2003): Comparative susceptibility of Streptococcus pneumoniae, cultured from patients in Great Britain and Ireland with community-acquired lower respiratory tract infection, to gemifloxacin
    • Felmingham D, Shackcloth J, Tillotson G. BSAC Respiratory Resistance Surveillance Programme (2002-2003): comparative susceptibility of Streptococcus pneumoniae, cultured from patients in Great Britain and Ireland with community-acquired lower respiratory tract infection, to gemifloxacin. J Antimicrob Chemother 2004; 54: 69 8-699.
    • (2004) J Antimicrob Chemother , vol.54 , Issue.69 , pp. 8-699
    • Felmingham, D.1    Shackcloth, J.2    Tillotson, G.3
  • 7
    • 84863144659 scopus 로고    scopus 로고
    • Prevalence of atypical pathogens in adult patients with community-acquired pneumonia in Beijing
    • Liu YN, Zhao TM, Yao WZ, Zhang LS, He ZY, Jiao YM, et al. Prevalence of atypical pathogens in adult patients with community-acquired pneumonia in Beijing. Chin J Tuberc Respir Dis (Chin) 2004; 27: 2 7-30.
    • (2004) Chin J Tuberc Respir Dis (Chin) , vol.27 , Issue.2 , pp. 7-30
    • Liu, Y.N.1    Zhao, T.M.2    Yao, W.Z.3    Zhang, L.S.4    He, Z.Y.5    Jiao, Y.M.6
  • 8
    • 0034989717 scopus 로고    scopus 로고
    • Susceptibility of Canadian isolates of Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae to oral antimicrobial agents
    • Blondeau JM, Vaughan D, Laskowski R, Borsos S. Susceptibility of Canadian isolates of Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae to oral antimicrobial agents. Int J Antimicrob Agents 2001; 17: 45 7-464.
    • (2001) Int J Antimicrob Agents , vol.17 , Issue.45 , pp. 7-464
    • Blondeau, J.M.1    Vaughan, D.2    Laskowski, R.3    Borsos, S.4
  • 9
    • 2942565876 scopus 로고    scopus 로고
    • Quinolone-resistant Haemophilus influenzae in a long-term care facility: Clinical and molecular epidemiology
    • Nazir J, Urban C, Mariano N, Burns J, Tommasulo B, Rosenberg C, et al. Quinolone-resistant Haemophilus influenzae in a long-term care facility: clinical and molecular epidemiology. Clin Infect Dis 2004; 38: 156 4-1569.
    • (2004) Clin Infect Dis , vol.38 , Issue.156 , pp. 4-1569
    • Nazir, J.1    Urban, C.2    Mariano, N.3    Burns, J.4    Tommasulo, B.5    Rosenberg, C.6
  • 10
    • 2342590604 scopus 로고    scopus 로고
    • Guidelines for management of chronic obstructive pulmonary disease (COPD) in India: A guide for physicians (2003)
    • Jindal SK, Gupta D, Aggarwal AN. Guidelines for management of chronic obstructive pulmonary disease (COPD) in India: a guide for physicians (2003). Indian J Chest Dis Allied Sci 2004; 46: 13 7-153.
    • (2004) Indian J Chest Dis Allied Sci , vol.46 , Issue.13 , pp. 7-153
    • Jindal, S.K.1    Gupta, D.2    Aggarwal, A.N.3
  • 11
    • 0037045689 scopus 로고    scopus 로고
    • Management of chronic obstructive pulmonary disease: The Swiss guidelines. Official Guidelines of the Swiss Respiratory Society
    • Russi EW, Leuenberger P, Brandli O, Frey JG, Grebski E, Gugger M, et al. Management of chronic obstructive pulmonary disease: the Swiss guidelines. Official Guidelines of the Swiss Respiratory Society. Swiss Med Wkly 2002; 132: 6 7-78.
    • (2002) Swiss Med Wkly , vol.132 , Issue.6 , pp. 7-78
    • Russi, E.W.1    Leuenberger, P.2    Brandli, O.3    Frey, J.G.4    Grebski, E.5    Gugger, M.6
  • 12
    • 0035430987 scopus 로고    scopus 로고
    • New international guidelines for chronic obstructive pulmonary disease
    • Pierson DJ. New international guidelines for chronic obstructive pulmonary disease. Respir Care 2001; 46: 76 8-771.
    • (2001) Respir Care , vol.46 , Issue.76 , pp. 8-771
    • Pierson, D.J.1
  • 13
    • 0032948829 scopus 로고    scopus 로고
    • Chronic bronchitis and chronic obstructive pulmonary disease: Finnish National Guidelines for Prevention and Treatment 199 8-2007
    • Laitinen LA, Koskela K. Chronic bronchitis and chronic obstructive pulmonary disease: Finnish National Guidelines for Prevention and Treatment 199 8-2007. Respir Med 1999; 93: 29 7-332.
    • (1999) Respir Med , vol.93 , Issue.29 , pp. 7-332
    • Laitinen, L.A.1    Koskela, K.2
  • 14
    • 33845291923 scopus 로고    scopus 로고
    • 13--Antibiotic therapy of community-acquired pneumonia (CAP) caused by atypical agents
    • Roig J, Casal J, Gispert P, Gea E. 13--Antibiotic therapy of community-acquired pneumonia (CAP) caused by atypical agents. Med Mal Infect 2006; 36: 680-689.
    • (2006) Med Mal Infect , vol.36 , Issue.68 , pp. 680-689
    • Roig, J.1    Casal, J.2    Gispert, P.3    Gea, E.4
  • 15
    • 67249101092 scopus 로고    scopus 로고
    • Increased macrolide resistance of Mycoplasma pneumoniae in France directly detected in clinical specimens by real-time PCR and melting curve analysis
    • Peuchant O, Menard A, Renaudin H, Morozumi M, Ubukata K, Bebear CM, et al. Increased macrolide resistance of Mycoplasma pneumoniae in France directly detected in clinical specimens by real-time PCR and melting curve analysis. J Antimicrob Chemother 2009; 64: 5 2-58.
    • (2009) J Antimicrob Chemother , vol.64 , Issue.5 , pp. 2-58
    • Peuchant, O.1    Menard, A.2    Renaudin, H.3    Morozumi, M.4    Ubukata, K.5    Bebear, C.M.6
  • 16
    • 66149117796 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China
    • Liu Y, Ye X, Zhang H, Xu X, Li W, Zhu D, et al. Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. Antimicrob Agents Chemother 2009; 53: 216 0-2162.
    • (2009) Antimicrob Agents Chemother , vol.53 , Issue.216 , pp. 0-2162
    • Liu, Y.1    Ye, X.2    Zhang, H.3    Xu, X.4    Li, W.5    Zhu, D.6
  • 17
    • 34948895653 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae isolated from patients with respiratory infection in Kanagawa Prefecture in 1976-2006: Emergence of macrolide-resistant strains
    • Okazaki N, Ohya H, Sasaki T. Mycoplasma pneumoniae isolated from patients with respiratory infection in Kanagawa Prefecture in 1976-2006: emergence of macrolide-resistant strains. Jpn J Infect Dis 2007; 60: 32 5-326.
    • (2007) Jpn J Infect Dis , vol.60 , Issue.32 , pp. 5-326
    • Okazaki, N.1    Ohya, H.2    Sasaki, T.3
  • 18
    • 68649089313 scopus 로고    scopus 로고
    • Emerging macrolide resistance in Mycoplasma pneumoniae in children: Detection and characterization of resistant isolates
    • Li X, Atkinson TP, Hagood J, Makris C, Duffy LB, Waites KB. Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates. Pediatr Infect Dis J 2009; 28: 69 3-696.
    • (2009) Pediatr Infect Dis J , vol.28 , Issue.69 , pp. 3-696
    • Li, X.1    Atkinson, T.P.2    Hagood, J.3    Makris, C.4    Duffy, L.B.5    Waites, K.B.6
  • 19
    • 33845691276 scopus 로고    scopus 로고
    • Monotherapy versus combination therapy in patients hospitalized with community-acquired pneumonia
    • Kolditz M, Halank M, Hoffken G. Monotherapy versus combination therapy in patients hospitalized with community-acquired pneumonia. Treat Respir Med 2006; 5: 37 1-383.
    • (2006) Treat Respir Med , vol.5 , Issue.37 , pp. 1-383
    • Kolditz, M.1    Halank, M.2    Hoffken, G.3
  • 20
    • 33845689355 scopus 로고    scopus 로고
    • Treating acute exacerbations of chronic bronchitis and community-acquired pneumonia: How effective are respiratory fluoroquinolones?
    • Balter M, Weiss K. Treating acute exacerbations of chronic bronchitis and community-acquired pneumonia: how effective are respiratory fluoroquinolones? Can Fam Physician 2006; 52: 123 6-1242.
    • (2006) Can Fam Physician , vol.52 , Issue.123 , pp. 6-1242
    • Balter, M.1    Weiss, K.2
  • 21
    • 21844459488 scopus 로고    scopus 로고
    • Antimicrobial resistance among Streptococcus pneumoniae in the United States: Have we begun to turn the corner on resistance to certain antimicrobial classes?
    • Doern GV, Richter SS, Miller A, Miller N, Rice C, Heilmann K, et al. Antimicrobial resistance among Streptococcus pneumoniae in the United States: have we begun to turn the corner on resistance to certain antimicrobial classes? Clin Infect Dis 2005; 41: 13 9-148.
    • (2005) Clin Infect Dis , vol.41 , Issue.13 , pp. 9-148
    • Doern, G.V.1    Richter, S.S.2    Miller, A.3    Miller, N.4    Rice, C.5    Heilmann, K.6
  • 22
    • 73249148504 scopus 로고    scopus 로고
    • MRSA as a cause of lung infection including airway infection, community-acquired pneumonia and hospital-acquired pneumonia
    • Defres S, Marwick C, Nathwani D. MRSA as a cause of lung infection including airway infection, community-acquired pneumonia and hospital-acquired pneumonia. Eur Respir J 2009; 34: 147 0-1476.
    • (2009) Eur Respir J , vol.34 , Issue.147 , pp. 0-1476
    • Defres, S.1    Marwick, C.2    Nathwani, D.3
  • 23
    • 64549135399 scopus 로고    scopus 로고
    • Activity of the new cephalosporin ceftaroline against bacteraemia isolates from patients with community-acquired pneumonia
    • Morrissey I, Ge Y, Janes R. Activity of the new cephalosporin ceftaroline against bacteraemia isolates from patients with community-acquired pneumonia. Int J Antimicrob Agents 2009; 33: 51 5-519.
    • (2009) Int J Antimicrob Agents , vol.33 , Issue.51 , pp. 5-519
    • Morrissey, I.1    Ge, Y.2    Janes, R.3
  • 24
    • 44849106202 scopus 로고    scopus 로고
    • Clinical evaluation of chinese guidelines for community-acquired pneumonia
    • Xue XY, Gao ZC, Zhu JH, Xu Y, Li X. Clinical evaluation of chinese guidelines for community-acquired pneumonia. J Peking Univ (Health Sci) (Chin) 2006; 38: 27 6-279.
    • (2006) J Peking Univ (Health Sci) (Chin) , vol.38 , Issue.27 , pp. 6-279
    • Xue, X.Y.1    Gao, Z.C.2    Zhu, J.H.3    Xu, Y.4    Li, X.5
  • 25
    • 75649115399 scopus 로고    scopus 로고
    • Gemifloxacin use in the treatment of acute bacterial exacerbation of chronic bronchitis
    • Jivcu C, Gotfried M. Gemifloxacin use in the treatment of acute bacterial exacerbation of chronic bronchitis. Int J Chron Obstruct Pulmon Dis 2009; 4: 29 1-300.
    • (2009) Int J Chron Obstruct Pulmon Dis , vol.4 , Issue.29 , pp. 1-300
    • Jivcu, C.1    Gotfried, M.2
  • 27
    • 33846023020 scopus 로고    scopus 로고
    • Geminofloxacin for the management of community-acquired respiratory tract infections
    • Blondeau JM, Tillotson G, Deangelis J. Geminofloxacin for the management of community-acquired respiratory tract infections. J Chemother 2006; 18: 58 2-588.
    • (2006) J Chemother , vol.18 , Issue.58 , pp. 2-588
    • Blondeau, J.M.1    Tillotson, G.2    Deangelis, J.3
  • 28
    • 18044381726 scopus 로고    scopus 로고
    • Gemifloxacin for the treatment of respiratory tract infections: In vitro susceptibility, pharmacokinetics and pharmacodynamics, clinical efficacy, and safety
    • Bhavnani SM, Andes DR. Gemifloxacin for the treatment of respiratory tract infections: in vitro susceptibility, pharmacokinetics and pharmacodynamics, clinical efficacy, and safety. Pharmacotherapy 2005; 25: 71 7-740.
    • (2005) Pharmacotherapy , vol.25 , Issue.71 , pp. 7-740
    • Bhavnani, S.M.1    Andes, D.R.2
  • 29
    • 0032558314 scopus 로고    scopus 로고
    • Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?
    • Moher D, Pham B, Jones A, Cook DJ, Jadad AR, Moher M, et al. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? Lancet 1998; 352: 60 9-613.
    • (1998) Lancet , vol.352 , Issue.60 , pp. 9-613
    • Moher, D.1    Pham, B.2    Jones, A.3    Cook, D.J.4    Jadad, A.R.5    Moher, M.6
  • 30
    • 57349155272 scopus 로고    scopus 로고
    • Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: A meta-analysis of randomized controlled trials
    • Vardakas KZ, Siempos, II, Grammatikos A, Athanassa Z, Korbila IP, Falagas ME. Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials. CMAJ 2008; 179: 126 9-1277.
    • (2008) CMAJ , vol.179 , Issue.126 , pp. 9-1277
    • Vardakas, K.Z.1    Siempos, I.I.2    Grammatikos, A.3    Athanassa, Z.4    Korbila, I.P.5    Falagas, M.E.6
  • 31
    • 34250219979 scopus 로고    scopus 로고
    • Macrolides, quinolones and amoxicillin/clavulanate for chronic bronchitis: A meta-analysis
    • Siempos II, Dimopoulos G, Korbila IP, Manta K, Falagas ME. Macrolides, quinolones and amoxicillin/clavulanate for chronic bronchitis: a meta-analysis. Eur Respir J 2007; 29: 112 7-1137.
    • (2007) Eur Respir J , vol.29 , Issue.112 , pp. 7-1137
    • Siempos, I.I.1    Dimopoulos, G.2    Korbila, I.P.3    Manta, K.4    Falagas, M.E.5
  • 32
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 62 9-634.
    • (1997) BMJ , vol.315 , Issue.62 , pp. 9-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 33
    • 0035189486 scopus 로고    scopus 로고
    • Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: A randomized, double-blind comparison with trovafloxacin
    • Hammerschlag MR. Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: a randomized, double-blind comparison with trovafloxacin. J Antimicrob Chemother 2001; 48: 735.
    • (2001) J Antimicrob Chemother , vol.48 , pp. 735
    • Hammerschlag, M.R.1
  • 34
    • 84863165862 scopus 로고    scopus 로고
    • Short course (5 day) Gemifloxacin therapy is as at least as effective as 7 day Levofloxavin in the treatment of acute exacerbations of chronic bronchitis
    • Niederman M, Wilson R, Seltzer E. Short course (5 day) Gemifloxacin therapy is as at least as effective as 7 day Levofloxavin in the treatment of acute exacerbations of chronic bronchitis. Am J Respir Crit Care Med 2002; 165 Suppl: s279.
    • (2002) Am J Respir Crit Care Med , vol.165 , Issue.SUPPL.
    • Niederman, M.1    Wilson, R.2    Seltzer, E.3
  • 35
    • 10744227363 scopus 로고    scopus 로고
    • Clinical characteristics and response to newer quinolones in Legionella pneumonia: A report of 28 cases
    • Santos J, Aguilar L, Garcia-Mendez E, Siquier B, Custardoy J, Garcia-Rey C, et al. Clinical characteristics and response to newer quinolones in Legionella pneumonia: a report of 28 cases. J Chemother 2003; 15: 46 1-465.
    • (2003) J Chemother , vol.15 , Issue.46 , pp. 1-465
    • Santos, J.1    Aguilar, L.2    Garcia-Mendez, E.3    Siquier, B.4    Custardoy, J.5    Garcia-Rey, C.6
  • 36
    • 84863171298 scopus 로고    scopus 로고
    • 5 Days oral gemifloxacin compared to 7 days oral levofloxacin in the treatment of acute exacerbation of chronic bronchitis
    • Glenn S, Tillotson, Fulambarker A. 5 Days oral gemifloxacin compared to 7 days oral levofloxacin in the treatment of acute exacerbation of chronic bronchitis. Chest 2004; 126 Suppl: s839.
    • (2004) Chest , vol.126 , Issue.SUPPL.
    • Glenn, S.1    Tillotson, F.A.2
  • 37
    • 84863124311 scopus 로고    scopus 로고
    • Oral gemifloxacin vs. sequential I.V. ceftriaxone followed by oral cefuoxime in the treatment of hospitalized patients with acute exacerbations of chronic bronchitis
    • Wilson R, Ball P, Pypstra R. Oral gemifloxacin vs. sequential I.V. ceftriaxone followed by oral cefuoxime in the treatment of hospitalized patients with acute exacerbations of chronic bronchitis. Am J Respir Crit Care Med 2002; 165 Suppl: s270.
    • (2002) Am J Respir Crit Care Med , vol.165 , Issue.SUPPL.
    • Wilson, R.1    Ball, P.2    Pypstra, R.3
  • 38
    • 84863142286 scopus 로고    scopus 로고
    • Gemifloxacin produces greater improvement in health status of smokers and ex-smokers treated for acute exacerbations of chronic bronchitis compared to clarithromycin
    • Spencer S. Gemifloxacin produces greater improvement in health status of smokers and ex-smokers treated for acute exacerbations of chronic bronchitis compared to clarithromycin. Am J Respir Crit Care Med 2001; 163 Suppl: s507.
    • (2001) Am J Respir Crit Care Med , vol.163 , Issue.SUPPL.
    • Spencer, S.1
  • 39
    • 0037677450 scopus 로고    scopus 로고
    • Time course of recovery of health status following an infective exacerbation of chronic bronchitis
    • Spencer S, Jones PW. Time course of recovery of health status following an infective exacerbation of chronic bronchitis. Thorax 2003; 58: 58 9-593.
    • (2003) Thorax , vol.58 , Issue.58 , pp. 9-593
    • Spencer, S.1    Jones, P.W.2
  • 40
    • 0032730502 scopus 로고    scopus 로고
    • Evaluation of phototoxic potential of gemifloxacin in healthy volunteers compared with ciprofloxacin
    • Vousden M, Ferguson J, Richards J, Bird N, Allen A. Evaluation of phototoxic potential of gemifloxacin in healthy volunteers compared with ciprofloxacin. Chemotherapy 1999; 45: 51 2-520.
    • (1999) Chemotherapy , vol.45 , Issue.51 , pp. 2-520
    • Vousden, M.1    Ferguson, J.2    Richards, J.3    Bird, N.4    Allen, A.5
  • 41
    • 0034968690 scopus 로고    scopus 로고
    • Efficacy of gemifloxacin in acute exacerbations of chronic bronchitis: A randomised, double-blind comparison with trovafloxacin
    • Ball P, Wilson R, Mandell L, Brown J, Henkel T. Efficacy of gemifloxacin in acute exacerbations of chronic bronchitis: a randomised, double-blind comparison with trovafloxacin. J Chemother 2001; 13: 28 8-298.
    • (2001) J Chemother , vol.13 , Issue.28 , pp. 8-298
    • Ball, P.1    Wilson, R.2    Mandell, L.3    Brown, J.4    Henkel, T.5
  • 42
    • 0033889336 scopus 로고    scopus 로고
    • Gemifloxacin versus amoxicillin/clavulanate in the treatment of acute exacerbations of chronic bronchitis. The 070 Clinical Study group
    • File T, Schlemmer B, Garau J, Lode H, Lynch S, Young C. Gemifloxacin versus amoxicillin/clavulanate in the treatment of acute exacerbations of chronic bronchitis. The 070 Clinical Study group. J Chemother 2000; 12: 31 4-325.
    • (2000) J Chemother , vol.12 , Issue.31 , pp. 4-325
    • File, T.1    Schlemmer, B.2    Garau, J.3    Lode, H.4    Lynch, S.5    Young, C.6
  • 43
    • 0034916311 scopus 로고    scopus 로고
    • Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: A randomized, double-blind comparison with trovafloxacin
    • File TM Jr, Schlemmer B, Garau J, Cupo M, Young C. Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: a randomized, double-blind comparison with trovafloxacin. J Antimicrob Chemother 2001; 48: 6 7-74.
    • (2001) J Antimicrob Chemother , vol.48 , Issue.6 , pp. 7-74
    • File Jr., T.M.1    Schlemmer, B.2    Garau, J.3    Cupo, M.4    Young, C.5
  • 44
    • 3042589219 scopus 로고    scopus 로고
    • Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin
    • Leophonte P, File T, Feldman C. Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin. Respir Med 2004; 98: 70 8-720.
    • (2004) Respir Med , vol.98 , Issue.70 , pp. 8-720
    • Leophonte, P.1    File, T.2    Feldman, C.3
  • 45
    • 0036861678 scopus 로고    scopus 로고
    • Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalized with community-acquired pneumonia: A randomized, open-label, multicenter study of clinical efficacy and tolerability
    • Lode H, File TM Jr, Mandell L, Ball P, Pypstra R, Thomas M. Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalized with community-acquired pneumonia: a randomized, open-label, multicenter study of clinical efficacy and tolerability. Clin Ther 2002; 24: 191 5-1936.
    • (2002) Clin Ther , vol.24 , Issue.191 , pp. 5-1936
    • Lode, H.1    File Jr., T.M.2    Mandell, L.3    Ball, P.4    Pypstra, R.5    Thomas, M.6
  • 46
    • 3042551134 scopus 로고    scopus 로고
    • A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis
    • Sethi S, Fogarty C, Fulambarker A. A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis. Respir Med 2004; 98: 69 7-707.
    • (2004) Respir Med , vol.98 , Issue.69 , pp. 7-707
    • Sethi, S.1    Fogarty, C.2    Fulambarker, A.3
  • 47
    • 84863167884 scopus 로고    scopus 로고
    • Gemifloxacin versus levofloxacin in treatment of lower respiratory tract infection: A randomized controlled trial
    • Shi HY, Huang ZY, Huang YH, Fan Y, Shen MQ, Qiu YQ. Gemifloxacin versus levofloxacin in treatment of lower respiratory tract infection: a randomized controlled trial. Chin J New Drugs Clin Rem (Chin) 2007; 26: 67 8-680.
    • (2007) Chin J New Drugs Clin Rem (Chin) , vol.26 , Issue.67 , pp. 8-680
    • Shi, H.Y.1    Huang, Z.Y.2    Huang, Y.H.3    Fan, Y.4    Shen, M.Q.5    Qiu, Y.Q.6
  • 48
    • 0037370249 scopus 로고    scopus 로고
    • Oral gemifloxacin once daily for 5 days compared with sequential therapy with i.v. ceftriaxone/oral cefuroxime (maximum of 10 days) in the treatment of hospitalized patients with acute exacerbations of chronic bronchitis
    • Wilson R, Langan C, Ball P, Bateman K, Pypstra R. Oral gemifloxacin once daily for 5 days compared with sequential therapy with i.v. ceftriaxone/oral cefuroxime (maximum of 10 days) in the treatment of hospitalized patients with acute exacerbations of chronic bronchitis. Respir Med 2003; 97: 24 2-249.
    • (2003) Respir Med , vol.97 , Issue.24 , pp. 2-249
    • Wilson, R.1    Langan, C.2    Ball, P.3    Bateman, K.4    Pypstra, R.5
  • 49
    • 0036255914 scopus 로고    scopus 로고
    • A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes
    • Wilson R, Schentag JJ, Ball P, Mandell L. A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes. Clin Ther 2002; 24: 63 9-652.
    • (2002) Clin Ther , vol.24 , Issue.63 , pp. 9-652
    • Wilson, R.1    Schentag, J.J.2    Ball, P.3    Mandell, L.4
  • 50
    • 84863118911 scopus 로고    scopus 로고
    • A study of the effectiveness of gemifloxacin on chronic obstructive pulmonary disease
    • Yao ZP. A study of the effectiveness of gemifloxacin on chronic obstructive pulmonary disease. Pract Clin Med 2008; 9: 3 6-37.
    • (2008) Pract Clin Med , vol.9 , Issue.3 , pp. 6-37
    • Yao, Z.P.1
  • 51
    • 0043156138 scopus 로고    scopus 로고
    • The Alexander Project 1998-2000: Susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents
    • Jacobs MR, Felmingham D, Appelbaum PC, Gruneberg RN. The Alexander Project 1998-2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. J Antimicrob Chemother 2003; 52: 22 9-246.
    • (2003) J Antimicrob Chemother , vol.52 , Issue.22 , pp. 9-246
    • Jacobs, M.R.1    Felmingham, D.2    Appelbaum, P.C.3    Gruneberg, R.N.4
  • 52
    • 0033926264 scopus 로고    scopus 로고
    • Quinolone generations: Natural history or natural selection?
    • Ball P. Quinolone generations: natural history or natural selection? J Antimicrobial Chemotherapy 2000; 46: 1 7-24.
    • (2000) J Antimicrobial Chemotherapy , vol.46 , Issue.1 , pp. 7-24
    • Ball, P.1
  • 53
    • 0033839497 scopus 로고    scopus 로고
    • The fluoroquinolone antibacterials: Past, present and future perspectives
    • Appelbaum PC, Hunter PA. The fluoroquinolone antibacterials: past, present and future perspectives. Int J Antimicrob Agents 2000; 16: 5-15.
    • (2000) Int J Antimicrob Agents , vol.16 , pp. 5-15
    • Appelbaum, P.C.1    Hunter, P.A.2
  • 54
    • 0036178134 scopus 로고    scopus 로고
    • A critical review of the fluoroquinolones: Focus on respiratory infections
    • Zhanel GG, Ennis K, Vercaigne L, Walkty A, Gin AS, Embil J, et al. A critical review of the fluoroquinolones: focus on respiratory infections. Drugs 2002; 62: 1 3-59.
    • (2002) Drugs , vol.62 , Issue.1 , pp. 3-59
    • Zhanel, G.G.1    Ennis, K.2    Vercaigne, L.3    Walkty, A.4    Gin, A.S.5    Embil, J.6


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