Catalytic mechanism of Sep-tRNA:Cys-tRNA synthase: Sulfur transfer is mediated by disulfide and persulfide

Journal of Biological Chemistry

Volumn 287, Issue 8, 2012, Pages 5426-5433

  Liu, Yuchen ^a   Dos Santos, Patricia C ^b   Zhu, Xiang ^c   Orlando, Ron ^c   Dean, Dennis R ^d   So, Dieter ^a   Yuan, Jing ^a  

^a YALE UNIVERSITY   (United States)

^b WAKE FOREST UNIVERSITY   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

^d VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; ARCHAEOGLOBUS FULGIDUS; CATALYTIC MECHANISMS; COFACTORS; COMPLEMENTATION; CYS RESIDUES; CYSTEINE BIOSYNTHESIS; DISULFIDE LINKAGES; IN-VIVO; MASS SPECTROMETRIC ANALYSIS; PYRIDOXAL PHOSPHATES; SUBSTRATE BINDING; SULFUR DONORS; SULFUR TRANSFER; SYNTHASES; SYNTHETASES;

AMINO ACIDS; BIOCHEMISTRY; ENZYMES; ESCHERICHIA COLI; SULFUR COMPOUNDS;

SULFUR;

BACTERIAL ENZYME; O PHOSPHOSERINE TRANSFER RNA:CYSTEINYL TRANSFER RNA SYNTHETASE; UNCLASSIFIED DRUG;

ACYLATION; ARCHAEOGLOBUS FULGIDUS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; IN VIVO STUDY; MASS SPECTROMETRY; METHANOCALDOCOCCUS JANNASCHII; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PURIFICATION; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; AMINO ACYL-TRNA SYNTHETASES; ARCHAEOGLOBUS FULGIDUS; BIOCATALYSIS; CONSERVED SEQUENCE; CYSTEINE; DISULFIDES; MASS SPECTROMETRY; METHANOCOCCALES; MOLECULAR SEQUENCE DATA; PHOSPHOSERINE; SULFIDES; SULFUR;

EID: 84863116891     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.313700     Document Type: Article

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