D -Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain

British Journal of Pharmacology

Volumn 165, Issue 6, 2012, Pages 1941-1955

  Lu, Jin Miao ^a   Gong, Nian ^a   Wang, Yan Chao ^a   Wang, Yong Xiang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

CBIO (5 chloro benzo d isoxazol 3 ol); central sensitization; d amino acid oxidase (DAAO); d serine; formalin induced tonic pain; hydrogen peroxide; spinal cord

Indexed keywords

5 CHLOROBENZO[D]ISOXAZOL 3 OL; ANALGESIC AGENT; CATALASE; DEXTRO AMINO ACID OXIDASE; DEXTRO SERINE; FLUOROCITRIC ACID; FORMALDEHYDE; HYDROGEN PEROXIDE; N TERT BUTYL ALPHA PHENYLNITRONE; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; ENZYME INHIBITION; HYPERALGESIA; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; TONIC PAIN;

ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; D-AMINO-ACID OXIDASE; FORMALDEHYDE; HYDROGEN PEROXIDE; HYPERALGESIA; ISOXAZOLES; MALE; MICE; PAIN; RATS; RATS, WISTAR; SERINE; SPINE;

EID: 84863115550     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01680.x     Document Type: Article

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