Genome-wide association study identifies candidate markers for bull fertility in Holstein dairy cattle

Animal Genetics

Volumn 43, Issue SUPPL. 1, 2012, Pages 65-71

  Penagaricano F ^a   Weigel, K A ^a   Khatib, H ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

association study; bull fertility; cattle; single nucleotide polymorphism

Indexed keywords

ANIMAL; ARTICLE; BREEDING; CATTLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME; FEMALE; FERTILITY; FERTILIZATION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC MARKER; GENETICS; MALE; MEIOSIS; METABOLISM; METHODOLOGY; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; SPERMATOGENESIS; SPERMATOZOON;

ANIMALS; BREEDING; CATTLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOMES, MAMMALIAN; FEMALE; FERTILITY; FERTILIZATION; GENETIC MARKERS; GENOME-WIDE ASSOCIATION STUDY; LINKAGE DISEQUILIBRIUM; MALE; MEIOSIS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SPERMATOGENESIS; SPERMATOZOA;

BOS; BOVINAE;

EID: 84863111465     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2012.02350.x     Document Type: Article

References (34)

1. Bootman M.D., Collins T.J., Peppiatt C.M., et al,. (2001) Calcium signalling-an overview. Seminars in Cell and Developmental Biology 12, 3-10.
2. Braundmeier A.G., &, Miller D.J., (2001) The search is on: finding accurate molecular markers of male fertility. Journal of Dairy Science 84, 1915-25.
3. Brucker C., &, Lipford G.B., (1995) The human sperm acrosome reaction: physiology and regulatory mechanisms. An update. Human Reproduction Update 1, 51-62.
4. Choi E., Han C., Park I., Lee B., Jin S., Choi H., Kim do H., Park Z.Y., Eddy E.M., &, Cho C., (2008) A novel germ cell-specific protein, SHIP1, forms a complex with chromatin remodeling activity during spermatogenesis. The Journal of Biological Chemistry 283, 35283-94.
5. Cribbs L.L., Lee J.H., Yang J., et al,. (1998) Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2 + channel gene family. Circulation Research 83, 103-9.
6. DeJarnette J.M., Marshall C.E., Lenz R.W., Monke D.R., Ayars W.H., &, Sattler C.G., (2004) Sustaining the fertility of artificially inseminated dairy cattle: the role of the artificial insemination industry. Journal of Dairy Science 87, E93-104.
7. Druet T., Fritz S., Sellem E., Basso B., Gérard O, Salas-Cortes L., Humblot P., Druart X., &, Eggen A., (2009) Estimation of genetic parameters and genome scan for 15 semen characteristics traits of Holstein bulls. Journal of Animal Breeding and Genetics 126, 269-77.
8. Falconer D.S., &, Mackay T.F.C., (1996) Introduction to Quantitative Genetics, 4th edn. Longman, Essex, UK.
9. Feugang J.M., Kaya A., Page G.P., Chen L., Mehta T., Hirani K., Nazareth L., Topper E., Gibbs R., &, Memili E., (2009) Two-stage genome-wide association study identifies integrin beta 5 as having potential role in bull fertility. BMC Genomics 10, 176.
10. Feugang J.M., Rodriguez-Osorio N., Kaya A., Wang H., Page G., Ostermeier G.C., Topper E.K., &, Memili E., (2010) Transcriptome analysis of bull spermatozoa: implications for male fertility. Reproductive BioMedicine Online 21, 312-24.
11. Gao X., Starmer J., &, Martin E.R., (2008) A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genetic Epidemiology 32, 361-9.
12. Gao X., Becker L.C., Becker D.M., Starmer J.D., &, Province M.A., (2010) Avoiding the high Bonferroni penalty in genome-wide association studies. Genetic Epidemiology 34, 100-5.
13. Gaviraghi A., Deriu F., Soggiu A., Galli A., Bonacina C., Bonizzi L., &, Roncada P., (2010) Proteomics to investigate fertility in bulls. Veterinary Research Communications 34, S33-6.
14. Hooper J.D., Nicol D.L., Dickinson J.L., et al,. (1999) Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors. Cancer Research 59, 3199-205.
15. Johnson R.C., Nelson G.W., Troyer J.L., Lautenberger J.A., Kessing B.D., Winkler C.A., &, O'Brien S.J., (2010) Accounting for multiple comparisons in a genome-wide association study (GWAS). BMC Genomics 11, 724.
16. Khatib H., Monson R.L., Huang W., Khatib R., Schutzkus V., Khateeb H., &, Parrish J.J., (2010) Short communication: validation of in vitro fertility genes in a Holstein bull population. Journal of Dairy Science 93, 2244-9.
17. Kim E.S., &, Kirkpatrick B.W., (2009) Linkage disequilibrium in the North American Holstein population. Animal Genetics 40, 279-88.
18. Kuhn M.T., &, Hutchison J.L., (2008) Prediction of dairy bull fertility from field data: use of multiple services and identification and utilization of factors affecting bull fertility. Journal of Dairy Science 91, 2481-92.
19. Kuhn M.T., Hutchison J.L., &, Norman H.D., (2008) Modeling nuisance variables for prediction of service sire fertility. Journal of Dairy Science 91, 2823-35.
20. Li M.G., Serr M., Newman E.A., &, Hays T.S., (2004) The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation. Molecular Biology of the Cell 15, 3005-14.
21. Lucy M.C., (2001) Reproductive loss in high-producing dairy cattle: where will it end? Journal of Dairy Science 84, 1277-93.
22. Luitjens C., Gallegos M., Kraemer B., Kimble J., &, Wickens M., (2000) CPEB proteins control two key steps in spermatogenesis in C. elegans. Genes and Development 14, 2596-609.
23. Massé K., Bhamra S., Allsop G., Dale N., &, Jones E.A., (2010) Ectophosphodiesterase/nucleotide phosphohydrolase (Enpp) nucleotidases: cloning, conservation and developmental restriction. The International Journal of Developmental Biology 54, 181-93.
24. McClure M.C., Morsci N.S., Schnabel R.D., et al,. (2010) A genome scan for quantitative trait loci influencing carcass, post-natal growth and reproductive traits in commercial Angus cattle. Animal Genetics 41, 597-607.
25. Miglior F., Muir B.L., &, Van Doormaal B.J., (2005) Selection indices in Holstein cattle of various countries. Journal of Dairy Science 88, 1255-63.
26. Peddinti D., Nanduri B., Kaya A., Feugang J.M., Burgess S.C., &, Memili E., (2008) Comprehensive proteomic analysis of bovine spermatozoa of varying fertility rates and identification of biomarkers associated with fertility. BMC Systems Biology 2, 19.
27. Pfister K.K., Shah P.R., Hummerich H., Russ A., Cotton J., Annuar A.A., King S.M., &, Fisher E.M, (2006) Genetic analysis of the cytoplasmic dynein subunit families. PLoS Genetics 2, e1.
28. Pryce J.E., Royal M.D., Garnsworthy P.C., &, Mao I.L., (2004) Fertility in the high producing dairy cow. Livestock Production Science 86, 125-35.
29. R Development Core Team (2009) R: A Language and Environment for Statistical Computing. In: R Foundation for Statistical Computing. Vienna, Austria.
30. Steffen D., (1997) Genetic causes of bull infertility. Veterinary Clinics of North American: Food Animal Practice 13, 243-53.
31. Tulin E.E., Onoda N., Hasegawa M., Nosaka T., Nomura H., &, Kitamura T., (2002) Genetic approach and phenotype-based complementation screening for identification of stroma cell-derived proteins involved in cell proliferation. Experimental Cell Research 272, 23-31.
32. Vazquez A.I., Bates D.M., Rosa G.J.M., Gianola D., &, Weigel K.A., (2010) Technical note: an r package for fitting generalized linear mixed models in animal breeding. Journal of Animal Science 88, 497-504.
33. Weigel K.A., (2006) Prospects for improving reproductive performance through genetic lection. Animal Reproduction Science 96, 323-30.
34. Xu S., (2003) Theoretical basis of the Beavis effect. Genetics 165, 2259-68.