The search is on: Finding accurate molecular markers of male fertility

Journal of Dairy Science

Volumn 84, Issue 9, 2001, Pages 1915-1925

  Braundmeier, A G ^a   Miller, D J ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Fertilization; Oocyte; Spermatozoa; Zona pellucida

Indexed keywords

FERTILITY PROMOTING AGENT;

ANIMAL; ANIMAL DISEASE; BIRD DISEASE; FEMALE; FERTILITY; FERTILIZATION IN VITRO; GENETIC MARKER; MALE; MALE INFERTILITY; OOCYTE; PHYSIOLOGY; POULTRY; PREDICTION AND FORECASTING; REPRODUCIBILITY; REVIEW; SPECIES DIFFERENCE; SPERM; SPERMATOZOON; SPERMATOZOON MOTILITY;

ANIMALS; FEMALE; FERTILITY; FERTILITY AGENTS, MALE; FERTILIZATION IN VITRO; GENETIC MARKERS; INFERTILITY, MALE; MALE; OOCYTES; POULTRY; POULTRY DISEASES; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SEMEN; SPECIES SPECIFICITY; SPERM MOTILITY; SPERMATOZOA;

EID: 0035465004     PISSN: 00220302     EISSN: None     Source Type: Journal    
DOI: 10.3168/jds.S0022-0302(01)74633-4     Document Type: Review

References (109)

1. Aitken, R. J., D. S. Irvine, and F. C. Wu. 1991. Prospective analysis of sperm-oocyte fusion and reactive oxygen species generation as criteria for the diagnosis of infertility. Am. J. Obstet. Gynecol. 164:542-551.
2. Amann, R. P., and R. H. Hammerstedt. 1993. In vitro evaluation of sperm quality: an opinion. J. Androl. 14:397-406.
3. Amann, R. P., G. E. Seidel, and Z. A. Brink. 1999. Exposure of thawed frozen bull sperm to a synthetic peptide befoe artificial insemination increases fertility. J. Androl. 20:42-46.
4. Auger, J., M. Mesbah, C. Huber, and J. P. Dadoune. 1990. Aniline blue staining as a marker of sperm chromatin defects associated with different semen characteristics discriminates between proven fertile and suspected infertile men. Int. J. Androl. 13:452-462.
5. Ax, R. L., K. Dickson, and R. W. Lenz. 1985. Induction of acrosome reactions by chondroitin sulfates in vitro corresponds to nonreturn rates of dairy bulls. J. Dairy Sci. 68:387-390.
6. Ax, R. L., and R. W. Lenz. 1987. Glycosaminoglycans as probes to monitor differences in fertility of bulls. J. Dairy Sci. 70:1477-1487.
7. Baba, T., S. Azuma, S. Kashiwabara, and Y. Toyada. 1994. Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate oocyte zona pellucida and affect fertilization. J. Biol. Chem. 269:31845-31849.
8. Baker, H. W., J. Brindle, D. S. Irvine, and R. J. Aitken. 1996. Protective effecto of antioxidants on the impairment of sperm motility by activated polymorphonuclear leukocytes. Fertil. Steril. 65:411-419.
9. Ballachey, B. E., D. P. Evenson, and R. G. Saacke. 1988. The sperm chromatin structure assay: Relationship with alternate tests of semen quality and heterospermic performance of bulls. J. Androl. 9:109-115.
10. Bellin, M. E., H. E. Hawkins, and R. L. Ax. 1994. Fertility of range beef bulls grouped according to presence or absence of heparin-binding proteins in sperm membranes and seminal fluid. J. Anim. Sci. 72:2441-2448.
11. Bellin, M. E., J. N. Ogarzo, H. E. Hawkins, H. M. Zhang, R. G. Smith, D. W. Forrest, L. R. Sprott, and R. L. Ax. 1998. Fertility-associated antigen on bull sperm indicates fertility potential. J. Anim. Sci. 76:2032-2039.
12. Belsey, M. A., K. S. Moghissi, A. Eliasson, C. A. Paulsen, A. J. Gallegos, and M. R. N. Prasad. 1980. Laboratory Manual for the Examination of Human Semen and Cervical Mucus Interaction, Singapore, Malaysia.
13. Berger, R. E., L. E. Karp, R. A. Williamson, J. Koehler, D. E. Moore, and K. K. Holmes. 1982. The relationship of pyospermia and seminal fluid bacteriology to sperm function as reflected in the sperm penetration assay. Fertil. Steril. 37:557-564.
14. Berube, B., and R. Sullivan. 1994. Inhibition of in vivo fertilization by active immunization of male hamsters against a 26 kDa sperm glycoprotein. Biol. Reprod. 51:1255-1263.
15. Bianchi, P. G., G. C. Manicardi, F. Urner, A. Campana, and D. Sakkas. 1996. Chromatin packing and morphology in ejaculated human spermatozoa: evidence of hidden anomalies in normal spermatozoa. Mol. Hum. Reprod. 2:139-144.
16. Bilgian, M. M., C. T. Taylor, P. R. Manasse, E. C. Joughin, C. R. Kingsland, and D. I. Lewis-Jones. 1994. Evaluation of different sperm function tests as screening methods for male fertilization potential - the value of the sperm migration test. Fertil. Steril. 62:591-598.
17. Boue, F., and R. Sullivan. 1996. Cases of human infertility are associated with the absence of P34H, an epididymal sperm antigen. Biol. Reprod. 54:1018-1024.
18. Caldamone, A. A., L. B. V. Emilson, A. Al-Juburi, and A. T. K. Cockett. 1980. Prostatitis: Prostatic secretory dysfucntion affecting fertility. Fertil. Steril. 34:602-603.
19. Cancel, A. M., D. A. Chapman, and G. J. Killian. 1997. Osteopontin is the 55-kilodalton fertility-associated protein in Holstein bull seminal plasma. Biol. Reprod. 57:1293-1301.
20. Cancel, A. M., D. A. Chapman, and G. J. Killian. 1999. Osteopontin localization in the Holstein bull reproductive tract. Biol. Reprod. 60:454-460.
21. Chan, S. Y., Y. M. Chan, M. J. Tucker, M. K. Leong, and C. K. Leung. 1990. The diagnostic value of seminal adenosine triphosphate (ATP) in an in vitro fertilization (IVF) program. Andrologia 22:531-537.
22. Coetzee, K, J. Olmedo, and C. J. Lombard. 1994. Induced acrosome reactions as fertility predictor. J. Assist. Reprod. Genet. 11:470-473.
23. Comhaire, F., L. Vermeulen, K. Ghedira, J. Mas, S. Irvine, and G. Callipolitis. 1983. Adenosine triphosphate in human semen: A quantitative estimate of fertilizing potential. Fertil. Steril. 40:500-504.
24. Cummins, J. M., S. M. Pember, A. M. Jequier, J. L. Yovich, and P. E. Hartmann. 1991. A test of the human sperm acrosome reaction following ionophore challenge. Relationship to fertility and other seminal parameters. J. Androl. 12:98-103.
25. Davis, A. P., J. K. Graham, and R. H. Foote. 1987. Homospermic versus heterospermic insemination of zona-free hamster eggs to assess fertility of fluorochrome-labeled acrosome reacted bull spermatozoa. Gamete Res. 17:343-354.
26. De los Reyes, M., and C. Barros. 2000. Immunolocalization of proacrosin/acrosin in bovine sperm and sperm penetration through the zona pellucida. Anim. Reprod. Sci. 58:215-228.
27. DeJarnette, J. M., R. G. Saacke, J. H. Barne, and C. J. Vogler. 1992. Accessory sperm: their importance to fertility and embryo quality, and attempts to alter their numbers in artificially inseminated cattle. J. Anim. Sci. 70:484-491.
28. Esteves, S. C., R. K. Sharma, A. J. Thomas, and A. Agarwal. 1996. Suitability of the hypo-osmotic swelling test for assessing the viability of cryopreserved sperm. Fertil. Steril. 66:798-804.
29. Evenson, D. P. 1999. Loss of livestock breeding efficiency due to uncompensable sperm nuclear defects. Reprod. Fertil. Steril. 11:1-15.
30. Evenson, D. P., L. Thompson, and L. Jost. 1994. Flow cytometric evaluation of boar semen by the sperm chromatin structure assay as related to cryopreservation and fertility. Theriogenology 41:637-651.
31. Farrell, P. B., G. A. Presicce, C. C. Brockett, and R. H. Foote. 1998. Quantification of bull sperm characteristics measured by computer-assisted sperm analysis (CASA) and the relationship to fertility. Theriogenology 49:871-879.
32. Flowers, W. L. 1997. Management of boars for efficient semen production. J. Reprod. Fertil. 52:67-78.
33. Fouchecourt, S., S. Metayer, A. Locatelli, F. Dacheux, and J. Dacheux. 2000. Stallion epididymal fluid proteome: Qualitative and quantitative characterization, secretion and dynamic changes of major proteins. Biol. Reprod. 62:1790-1803.
34. Francavilla, S., A. Gabriele, R. Romano, L. Gianaroli, A. P. Ferraretti, and F. Francavilla. 1994. Sperm-zona pellucida binding of human sperm is correlated with the immunocytochemical presence of proacrosin and acrosin in the sperm heads but not with the proteolytic activity of acrosin. Fertil. Steril. 62:1226-1233.
35. Franken, D. R., T. F. Kruger, S. Oehninger, C. C. Coddington, C. Lombard, K. Smith, and G. D. Hodgen. 1993. The ability of the hemizona assay to predict human fertilization in different and consecutive in-vitro fertilization cycles. Hum. Reprod. 8:1240-1244.
36. Gadea, J., C. Matas, and X. Lucas. 1998. Prediction of porcine semen fertility by homologous in vitro penetration (hIVP) assay. Anim. Reprod. Sci. 56:95-108.
37. Gerena, R. L., D. Irikura, Y. Urade, N. Eguchi, D. A. Chapman, and G. J. Killian. 1998. Identification of a fertility-associated protein in bull seminal plasma as lipocalin-type prostaglandin D synthase. Biol. Reprod. 58:826-833.
38. Gergely, A., J. Szollosi, G. Falkai, B. Resch, L. Kovacs, and G. Huszar. 1999. Sperm creatine kinase activity in normospermic and oligozospermic Hungarian men. J. Assist. Reprod. Gen. 16:35-40.
39. Hall, J. L. 1981. Relationship between semen quality and human sperm penetration of zona-free hamster ova. Fertil. Steril. 35:457-463.
40. Handrow, R. R., R. W. Lenz, and R. L. Ax. 1982. Structural comparisons among glycosaminoglycans to promote an acrosome reaction in bovine spermatozoa. Biochem. Biophys. Res. Commun. 107:1326.
41. Harrison, R. A. P., and S. E. Vickers. 1990. Use of fluorescent probes to assess membrane integrity in mammalian spermatozoa. J. Reprod. Fertil. 88:343-352.
42. Henault, M. A., and G. J. Killian. 1996. Effect of homologous and heterologous seminal plasma on the fertilizing ability of ejaculated bull spermatozoa assessed by penetration of zona-free bovine oocytes. J. Reprod. Fertil. 108:199-204.
43. Holtz, W., and D. Smidt. 1976. The fertilizing capacity of epididymal spermatozoa in the pig. Reprod. Fertil. 46:227-229.
44. Howard, J. G., A. M. Donoghue, L. A. Johnston, and D. E. Wildt. 1993. Zona pellucida filtration of structurally abnormal spermatozoa and reduced fertilization in teratospermic cats. Biol. Reprod. 49:131-139.
45. Huszar, G., P. Patrizio, L. Vigue, M. Willets, C. Wilker, D. Adhoot, and L. Johnson. 1998. Cytoplasmic extrusion and the switch from creatine kinase B to M isoform are completed by the commencement of epididymal transport in human and stallion spermatozoa. J. Androl. 19:11-20.
46. Huszar, G., K. Stone, D. Dix, and L. Vigue. 2000. Putative creatine kinase M-isoform in human sperm is identified as the 70-kilodalton heat shock protein HspA2. Biol. Reprod. 63:925-932.
47. Huszar, G., and L. Vigue. 1993. Incomplete development of human spermatozoa is associated with increased creatine phosphokinase concentration and abnormal head morphology. Mol. Reprod. Devel. 34:292-298.
48. Huszar, G., L. Vigue, and M. Morshedi. 1992. Sperm creatine phosphokinase M-isoform ratios and fertilizing potential of men: A blinded study of 84 couples treated with in vitro fertilization. Fertil. Steril. 57:882-888.
49. Ibrahim, N. M., G. R. Glibert, K. J. Loseth, and B. G. Crabo. 2000. Correlation between clusterin-positive spermatozoa determined by flow cytometry in bull semen and fertility. J. Androl. 21:887-894.
50. Irvine, D. S., and R. J. Aitken. 1985. The value of adenosine triphophate (ATP) measurements in assessing the fertilizing ability of human spermatozoa. Fertil. Steril. 44:806-813.
51. Irvine, D. S., and R. J. Aitken. 1986. Clinical evaluation of the zonafree hamster egg penetration test in the management of the infertile couple. Prospective and retrospective studies. Int. J. Androl. Suppl. 6:97-112.
52. Januskauskas, A., A. Johannisson, L. Soderquist, and H. Rodriguez-Martinez. 2000. Assessment of sperm characteristics post-thaw and response to calcium ionophore in relation to fertility in Swedish dairy AI bulls. Theriogenology 53:859-875.
53. Jeyendran, R. S., H. H. van der Ven, M. Perez-Pelaez, B. G. Crabo, and L. J. D. Zaneveld. 1984. Development of an assay to assess the functional intergrity of the human sperm membrane and its relationship to other semen characteristics. J. Reprod. Fertil. 70:219-228.
54. Jones, R. 1991. Interaction of zona pellucida glycoproteins, sulphated carbohydrates and synthetic polymers with proacrosin, the putative egg-binding protein from mammalian spermatozoa. Development 111:1155-1163.
55. Killian, G. J., D. A. Chapman, and L. A. Rogowski. 1993. Fertility-associated proteins in Holstein bull seminal plasma. Biol. Reprod. 49:1202-1207.
56. Kim, C. A., J. J. Parrish, H. W. Momont, and D. P. Lunn. 1999. Effects of experimentally generated bull antisperm antibodies on in vitro fertilization. Biol. Reprod. 60:1285-1291.
57. Lane, M. E., I. Therien, R. Moreau, and P. Manjunath. 1999. Heparin and high-density lipoprotein mediate bovine sperm capacitation by different mechanisms. Biol. Reprod. 60:169-175.
58. Larsson, B., and H. Rodriguez-Martinez. 2000. Can we use in vitro fertilization tests to predict semen fertility? Anim. Reprod. Sci. 60-61:327-336.
59. Lenz, R. W., G. D. Ball, J. K. Lohse, N. L. First, and R. L. Ax. 1983a. Chondroitin sulfate facilitates an acrosome reaction in bovine spermatozoa as evidenced by light microscopy, electron microscopy and in vitro fertilization. Biol. Reprod. 28:683-690.
60. Lenz, R. W., M. E. Bellin, and R. L. Ax. 1983b. Rabbit spermatozoa undergo an acrosome reaction in the presence of glycosaminoglycans. Gamete Res. 8:11.
61. Lenz, R. W., J. L. Martin, M. E. Bellin, and R. L. Ax. 1988. Predicting fertility of dairy bulls by inducing acrosome reactions in sperm with chondroitin sulfates. J. Dairy Sci. 71:1073-1077.
62. Liu, D. Y., and H. W. Baker. 1988. The proportion of human sperm with poor morphology but normal intact acrosomes detected with Pisum sativum agglutinin correlates with fertilization in vitro. Fertil. Steril. 50:288-293.
63. Liu, D. Y., and H. W. Baker. 1990. Relationships between human sperm acrosin, acrosomes, morphology and fertilization in vitro. Hum. Reprod. 5:298-303.
64. Mao, C., and D. A. Grimes. 1988. The sperm penetration assay: Can it discriminate between fertile and infertile men? Am. J. Obstet. Gynecol. 159:279-286.
65. Marks, J. L., and R. L. Ax. 1985. Relationship of nonreturn rates of dairy bulls to binding affinity of heparin to sperm. J. Dairy Sci. 68:2078-2082.
66. Maruyama, D. K., R. W. Hale, and B. J. Rogers. 1985. Effects of white blood cells on the in vitro penetration of zona-free hamster eggs by human spermatozoa. J. Androl. 6:127-135.
67. McCauley, T. C., H. M. Zhang, M. E. Bellin, and R. L. Ax. 1999. Purification and characterization of fertility-associated antigen (FAA) in bovine seminal fluid. Mol. Reprod. Dev. 54:145-153.
68. McCauley, T. C., H. M. Zhang, M. E. Bellin, and R. L. Ax. 2001. Identification of a heparin-binding protein in bovine seminal fluid as tissue inhibitor of metalloproteinases-2. Mol. Reprod. Dev. 58:336-341.
69. Megory, E., Z. Shoham, I. Madgar, B. Lunenfeld, M. Modan, and R. Weissenberg. 1987. ATP content in human semen and sperm quality. Arch. Androl. 19:243-247.
70. Miller, D. J., J. M. Demers, A. G. Braundmeier, and M. L. Behrens. 1998. The use of two fluorescent dyes to identify sperm in a competitive binding assay to oocytes. J. Androl. 19:650-656.
71. Miller, D. J., M. A. Winer, and R. L. Ax. 1990. Heparin-binding proteins from seminal plasma bind to bovine spermatozoa and modulate capacitation by heparin. Biol. Reprod. 42:899-915.
72. Naz, R. K. 1987. Involvement of fertilization antigen (FA-1) in involuntary immunoinfertility in humans. J. Clin. Invest. 80:1375-1383.
73. Oehninger, S., C. C. Coddington, R. Scott, D. A. Franken, L. J. Burkman, A. A. Acosta, and G. D. Hodgen. 1989. Hemizona assay: Assessment of sperm dysfunction and prediction of in vitro fertilization outcome. Fertil. Steril. 51:665-670.
74. Overstreet, J. W., W. Cooper, and D. F. Katz. 1978. Sperm transport in the repoductive tract of the female rabbit. II. The sustained phase of transport. Biol. Reprod. 19:115-132.
75. Parent, S., L. Lefievre, Y. Brindle, and R. Sullivan. 1999. Bull subfertility is associated with low levels of a sperm membrane antigen. Mol. Reprod. Dev. 52:57-65.
76. Parrish, J. J., G. C. Ostermeier, and M. M. Pace. 1998. Fourier harmonic analysis of sperm morphology. Pages 25-31 in Proc. 17th Tech. Conf. Artific. Insem. Reprod. National Association of Animal Breeders, Milwaukee, WI.
77. Parrish, J. J., J. L. Susko-Parrish, R. R. Handrow, M. M. Sims, and N. L. First. 1989. Capacitation of bovine spermatozoa by oviduct fluid. Biol. Reprod. 40:1020-1025.
78. Parrish, J. J., J. L. Susko-Parrish, M. A. Winer, and N. L. First. 1988. Capacitation of bovine sperm by heparin. Biol. Reprod. 38:1171-1180.
79. Rogers, B. J. 1985. The sperm penetration assay: Its usefulness reevaluated. Fertil. Steril. 43:821.
80. Rolf, C., H. M. Behre, T. G. Cooper, B. Koppers, and E. Nieschlag. 1998. Creatine kinase activity in human spermatozoa and seminal plasma lacks predictive value for male fertility in in vitro fertilization. Fertil. Steril. 69:727-734.
81. Rota, A., N. Penzo, L. Vincenti, and R. Mantovani. 2000. Hypoosmotic swelling (HOS) as a screening assay for testing in vitro fertility of bovine spermatozoa. Theriogenology 53:1415-1420.
82. Saacke, R. G., J. Bame, D. S. Karabinus, J. Mulins, and S. S. Whitman. 1988. Transport of abnormal sperm in the artificially inseminated cow based upon accessory sperm in the zona pellucida. Page 292 in 11th Int. Congress Animal Reproduction and Artificial Insemination. Vol. 3. Dublin, Ireland.
83. Saacke, R. G., J. C. Dalton, S. Nadir, R. L. Nebel, and J. H. Bame. 2000. Relationship of seminal traits and insemination time to fertilization rate and embryo quality. Anim. Reprod. Sci. 60-61:663-677.
84. Saacke, R. G., J. M. DeJarnette, J. H. Barne, D. S. Karabinus, and S. S. Whitman. 1998. Can spermatozoa with abnormal heads gain access to the ovum in artificially inseminated super-and single-ovulating cattle? Theriogenology 50:117-128.
85. Saacke, R. G., and J. M. White. 1972. Semen quality tests and their relationship to fertility. Pages 22-27 in Proc. 4th Natl. Assoc. Anim. Breeders Tech. Conf. Anim. Reprod. and Artificial Insemination, Milwaukee, WI.
86. Sailer, B. L., L. K. Jost, and D. P. Evenson. 1995. Mammalian sperm DNA susceptibility to in situ denaturation associated with the presence of DNa strand breaks as measured by the terminal deoxynucleotidyl transferase assay. J. Androl. 16:80-87.
87. Sakkas, D., F. Urner, P. G. Bianchi, D. Bizarro, I. Wagner, N. Jaquenoud, G. Manicardi, and A. Campana. 1996. Sperm chromatin anomalies can influence decondensation after intracytoplasmic sperm injection. Hum. Reprod. 11:837-843.
88. Sanchez-Prieto, J., J. Gonzalez, M. J. Illera, P. L. Lorenzo, and L. M. Orensanz. 1996. [3H]Heparin binding in boar spermatozoa: Characterization and correlation with routine semen quality parameters. Biol. Reprod. 55:860-867.
89. Schilling, E., and M. Vengust. 1987. Frequency of semen collection in boars and quality of ejaculates as evaluated by the osmotic resistance of acrosomal membranes. Anim. Reprod. Sci. 12:283-290.
90. Schneider, C. S., J. E. Ellington, and R. W. Wright. 1999. Relationship between bull field fertility and in vitro embryo production using sperm preparation methods with and without somatic cell coculture. Theriogenology 51:1085-1098.
91. Setchell, B. P. 1998. The Parkes Lecture: Heat and the Testis. J. Reprod. Fertil. 114:179-194.
92. Shimizu, Y., H. Kodama, J. Fukuda, and T. Tanaka. 1997. Evidence of proacrosin molecule abnormality as a possible cause of low acrosin activity and unexplained failure of fertilization in vitro. J. Androl. 18:281-288.
93. Siddequey, A. K. S., and J. Cohen. 1982. In vitro fertilization in the mouse and the relevance of different sperm/egg concentrations and volumes. J. Reprod. Fertil. 66:237-242.
94. Sprott, L. R., J. Young, D. W. Forrest, H. M. Zhang, J. N. Oyarzo, M. E. Bellin, and R. L. Ax. 2000. Artificial insemination outcomes in beef females using bovine sperm with a detectable fertility-associated antigen. J. Anim. Sci. 78:795-798.
95. Storey, B. T. 1997. Biochemistry of the induction and prevention of lipoperoxidative damage in human spermatozoa. Mol. Hum. Reprod. 3:203-214.
96. Suter, D., P. Y. Chow, and I. C. Martin. 1979. Maintenance of motility in human spermatozoa by energy derived through oxidation phosphorylation and addition of albumin. Biol. Reprod. 20:505-510.
97. Tardif, S., J. P. Laforest, N. Cormier, and J. L. Bailey. 1999. The importance of porcine sperm parameters on fertility in vivo. Theriogenology 52:447-459.
98. Thundathil, J., J. Gil, A. Januskauskas, B. Larsson, L. Soderquist, R. Mapletoft, and H. Rodriguez-Martinez. 1999. Relationship between the proportion of capacitated spermatozoa present in frozen-thawed bull semen and fertility with artificial insemination. Int. J. Androl. 22:366-373.
99. Uchida, A., K. Takahashi, and M. Kitao. 1992. Usefulness of the hypoosmotic swelling test for evaluation of human sperm fertilization. Hum. Reprod. 7:1264-1267.
100. Wassarman, P. M. 1999. Mammalian fertilization: molecular aspects of gamete adhesion, exocytosis, and fusion. Cell 96:175-183.
101. Williams, W. W. 1964. Sterility, the Diagnostic Survey of the Infertile Couple. W. W. Williams Incorporated, Springfield, MA.
102. Wolff, H., and D. J. Andreson. 1988. Evaluation of granulocyte elastase as a seminal plasma marker for leukocytospermia. Fertil. Steril. 50:129-132.
103. Wood, P. D., J. A. Foulkes, R. C. Shaw, and D. R. Melrose. 1986. Semen assessment, fertility and the selection of Hereford bulls for use in AI. J. Reprod. Fertil. 76:783-795.
104. Yanagimachi, R. 1994. Mammalian fertilization. Pages A189-A317 in Physiology of Reproduction. 2nd ed. E. Knobil and J. D. Neill, eds. Raven Press, New York.
105. Yanagimachi, R., H. Yanagimachi, and B. J. Rogers. 1976. The use of zona-free animal ova as a test system for the assessment of the fertilizing capacity of human spermatozoa. Biol. Reprod. 15:471.
106. Yee, B., and L. M. Cummings. 1988. Modification of the sperm penetration assay using human follicular fluid to minimize false negative results. Fertil. Steril. 50:123-128.
107. Zhang, B. R., B. Larsson, N. Lundeheim, M. G. H. Haard, and H. Rodriguez-Martinez. 1999. Prediction of bull fertility by combined in vitro assessments of frozen-thawed semen from young dairy bulls entering an Al-programme. Int. J. Androl. 22:253-260.
108. Zhang, B. R., B. Larsson, N. Lundeheim, and H. Rodriguez-Martinez. 1998. Sperm characteristics and zona pellucida binding in relation to field fertility of frozen-thawed semen from dairy AI bulls. Int. J. Androl. 21:207-216.
109. Zhang, B. R., B. Larsson, N. Lundeheim, and H. Rodriquez-Martinez. 1997. Relationship between embryo development in vitro and 56-day nonreturn rates of cows inseminated with frozen-thawed semen from dairy bulls. Theriogenology 48:221-231.