Saccharomyces cerevisiae MHF complex structurally resembles the histones (H3-H4) 2 heterotetramer and functions as a heterotetramer

Structure

Volumn 20, Issue 2, 2012, Pages 364-370

  Yang, Hui ^a,b   Zhang, Tianlong ^a   Tao, Ye ^a,b   Wu, Lijing ^a,b   Li, Hong Tao ^a   Zhou, Jin Qiu ^a   Zhong, Chen ^a   Ding, Jianping ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; ASPARTIC ACID; FANCM ASSOCIATED HISTONE FOLD PROTEIN 1; FANCM ASSOCIATED HISTONE FOLD PROTEIN 2; GLUTAMINE; GLYCINE; HETERODIMER; HETEROTETRAMER; HISTIDINE; HISTONE H3; HISTONE H4; LEUCINE; LYSINE; PHENYLALANINE; SACCHAROMYCES CEREVISIAE PROTEIN; SERINE; TETRAMER; UNCLASSIFIED DRUG; VALINE;

ALPHA HELIX; ARTICLE; CENTROMERE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA REPAIR; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; WILD TYPE;

AMINO ACID SUBSTITUTION; BINDING SITES; CARRIER PROTEINS; CHROMATOGRAPHY, GEL; CRYSTALLOGRAPHY, X-RAY; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; HISTONES; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STRUCTURAL HOMOLOGY, PROTEIN;

SACCHAROMYCES CEREVISIAE;

EID: 84863060036     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2011.12.012     Document Type: Article

References (25)

1. P.D. Adams, P.V. Afonine, G. Bunkóczi, V.B. Chen, I.W. Davis, N. Echols, J.J. Headd, L.W. Hung, G.J. Kapral, and R.W. Grosse-Kunstleve PHENIX: A comprehensive Python-based system for macromolecular structure solution Acta Crystallogr. D Biol. Crystallogr. 66 2010 213 221
2. M. Amano, A. Suzuki, T. Hori, C. Backer, K. Okawa, I.M. Cheeseman, and T. Fukagawa The CENP-S complex is essential for the stable assembly of outer kinetochore structure J. Cell Biol. 186 2009 173 182
3. G. Arents, and E.N. Moudrianakis Topography of the histone octamer surface: repeating structural motifs utilized in the docking of nucleosomal DNA Proc. Natl. Acad. Sci. USA 90 1993 10489 10493 (Pubitemid 23347067)
4. A.D. Baxevanis, G. Arents, E.N. Moudrianakis, and D. Landsman A variety of DNA-binding and multimeric proteins contain the histone fold motif Nucleic Acids Res. 23 1995 2685 2691
5. Collaborative Computational Project, Number 4 The CCP4 suite: Programs for protein crystallography Acta Crystallogr. D Biol. Crystallogr. 50 1994 760 763
6. C.A. Davey, D.F. Sargent, K. Luger, A.W. Maeder, and T.J. Richmond Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution J. Mol. Biol. 319 2002 1097 1113 (Pubitemid 34729421)
7. P. Emsley, and K. Cowtan Coot: Model-building tools for molecular graphics Acta Crystallogr. D Biol. Crystallogr. 60 2004 2126 2132 (Pubitemid 41742764)
8. I. Garcia-Higuera, T. Taniguchi, S. Ganesan, M.S. Meyn, C. Timmers, J. Hejna, M. Grompe, and A.D. D'Andrea Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway Mol. Cell 7 2001 249 262 (Pubitemid 32206493)
9. K. Gari, C. Décaillet, A.Z. Stasiak, A. Stasiak, and A. Constantinou The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks Mol. Cell 29 2008 141 148
10. T. Hori, M. Okada, K. Maenaka, and T. Fukagawa CENP-O class proteins form a stable complex and are required for proper kinetochore function Mol. Biol. Cell 19 2008 843 854 (Pubitemid 351481802)
11. T. Kokubo, D.W. Gong, J.C. Wootton, M. Horikoshi, R.G. Roeder, and Y. Nakatani Molecular cloning of Drosophila TFIID subunits Nature 367 1994 484 487
12. E. Krissinel, and K. Henrick Inference of macromolecular assemblies from crystalline state J. Mol. Biol. 372 2007 774 797 (Pubitemid 47321791)
13. R.A. Laskowski, M.W. MacArthur, D.S. Moss, and J.M. Thornton PROCHECK: A program to check the stereochemical quality of protein structures J. Appl. Crystallogr. 26 1993 283 291
14. G.L. Moldovan, and A.D. D'Andrea How the fanconi anemia pathway guards the genome Annu. Rev. Genet. 43 2009 223 249
15. G.N. Murshudov, A.A. Vagin, and E.J. Dodson Refinement of macromolecular structures by the maximum-likelihood method Acta Crystallogr. D Biol. Crystallogr. 53 1997 240 255 (Pubitemid 27235885)
16. Z. Otwinowski, and W. Minor Processing of X-ray diffraction data collected in oscillation mode C.W. Carter, R.M. Sweets, Methods in Enzymology 1997 University of Virginia Charlottesville, VA 307 326 (Pubitemid 27085611)
17. J.R. Pehrson, and V.A. Fried MacroH2A, a core histone containing a large nonhistone region Science 257 1992 1398 1400
18. A.E. Sims, E. Spiteri, R.J. Sims 3rd, A.G. Arita, F.P. Lach, T. Landers, M. Wurm, M. Freund, K. Neveling, and H. Hanenberg FANCI is a second monoubiquitinated member of the Fanconi anemia pathway Nat. Struct. Mol. Biol. 14 2007 564 567 (Pubitemid 46871814)
19. T.R. Singh, D. Saro, A.M. Ali, X.F. Zheng, C.H. Du, M.W. Killen, A. Sachpatzidis, K. Wahengbam, A.J. Pierce, and Y. Xiong MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM Mol. Cell 37 2010 879 886
20. A. Smogorzewska, S. Matsuoka, P. Vinciguerra, E.R. McDonald 3rd, K.E. Hurov, J. Luo, B.A. Ballif, S.P. Gygi, K. Hofmann, A.D. D'Andrea, and S.J. Elledge Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair Cell 129 2007 289 301 (Pubitemid 46584733)
21. A. Sobeck, S. Stone, and M.E. Hoatlin DNA structure-induced recruitment and activation of the Fanconi anemia pathway protein FANCD2 Mol. Cell. Biol. 27 2007 4283 4292 (Pubitemid 46906553)
22. L.H. Thompson, and J.M. Hinz Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: Mechanistic insights Mutat. Res. 668 2009 54 72
23. L.H. Thompson, and N.J. Jones Stabilizing and remodeling the blocked DNA replication fork: anchoring FANCM and the Fanconi anemia damage response Mol. Cell 37 2010 749 751
24. W. Wang Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins Nat. Rev. Genet. 8 2007 735 748 (Pubitemid 47429206)
25. Z. Yan, M. Delannoy, C. Ling, D. Daee, F. Osman, P.A. Muniandy, X. Shen, A.B. Oostra, H. Du, and J. Steltenpool A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability Mol. Cell 37 2010 865 878