Correlation of E-cadherin and CD44v6 expression with clinical pathology in esophageal carcinoma

Molecular Medicine Reports

Volumn 5, Issue 3, 2012, Pages 817-821

  Shen, Wei Dong ^a   Ji, Yong ^a   Liu, Peng Fei ^a   Xiang, Bin ^a   Chen, Guo Qiang ^a   Huang, Bin ^a   Wu, Song ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

CD44v6; Cell adhesion; E cadherin; Esophageal carcinoma; Immuno histochemistry

Indexed keywords

CD44V6 ANTIGEN; UVOMORULIN;

ADULT; AGED; ARTICLE; CANCER SURGERY; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DISTANT METASTASIS; ESOPHAGUS CARCINOMA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; PROTEIN EXPRESSION; TUMOR DIFFERENTIATION; TUMOR VOLUME;

ADULT; AGED; ANTIGENS, CD44; CADHERINS; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING;

EID: 84863055532     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.693     Document Type: Article

References (22)

1. Jemal A, Siegel R, Xu J and Ward E: Cancer statistics. CA Cancer J Clin 60: 277-300, 2010.
2. Rogers GJ, Hodgkin MN and Squires PE: E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet. Cell Physiol Biochem 20: 987-994, 2007. (Pubitemid 350059741)
3. Naor D, Wallach-Dayan SB, Zahalka MA and Sionov RV: Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin Cancer Biol 18: 260-267, 2008.
4. Liu YJ, Yan PS, Li J and Jia JF: Expression and significance of CD44s, CD44v6, and nm23 mRNA in human cancer. World J Gastroenterol 11: 6601-6606, 2005. (Pubitemid 43072697)
5. Giehl K and Menke A: Microenvironmental regulation of E-cadherin-mediated adherens junctions. Front Biosci 13: 3975-3985, 2008.
6. Yaldizl M, Hakverdi AU, Bayhan G and Akkuş Z: Expression of E-cadherin in squamous cell carcinomas of the cervix with correlations to clinicopathological features. Eur J Gynaecol Oncol 26: 95-98, 2005. (Pubitemid 40314078)
7. Harigopal M, Berger AJ, Camp RL, Rimm DL and Kluger HM: Automated quantitative analysis of E-cadherin expression in lymph node metastases is predictive of survival in invasive ductal breast cancer. Clin Cancer Res 11: 4083-4089, 2005. (Pubitemid 40791572)
8. Koksal IT, Ates M, Danisman A, Sezer C, Ciftcioglu A, Karpuzoglu G and Sevuk M: Reduced E-cadherin and alpha-catenin expressions have no prognostic role in bladder carcinoma. Pathol Oncol Res 12: 13-19, 2006.
9. Jeanes A, Gottardi CJ and Yap AS: Cadherins and cancers: how does cadherin dysfunction promote tumor progression? Oncogene 27: 6920-6929, 2008.
10. Michaylira CZ, Wong GS, Miller CG, et al: Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer. Cancer Res 70: 5281-5292, 2010.
11. Moh MC and Shen S: The role of cell adhesion molecules in tumor suppression and cell migration: a new paradox. Cell Adh Migr 3: 334-336, 2009.
12. Swisher SG, Hofstetter W, Wu TT, et al: Proposed revision of the esophageal cancer staging system to accommodate pathologic response (pP) following preoperative chemoradiation (CRT). Ann Surg 241: 817-820, 2005.
13. van Roy F and Berx G: The cell-cell adhesion molecule E-cadherin. Cell Mol Life Sci 65: 3756-88, 2008.
14. Wang L, Gao Y, Tu Q and Hong J: Expression of Ezrin and E-cadherin in nasopharyngeal carcinoma and its significance. Zhong Nan Da Xue Xue Bao Yi Xue Ban (in Chinese) 35: 969-975, 2010.
15. Dian D, Brüning A and Mylonas I: E-cadherin as a prognostic marker in human serous carcinomas of the ovary: an immunohistochemical analysis. Arch Gynecol Obstet 284: 437-443, 2011.
16. Jang TJ, Cha WH and Lee KS: Reciprocal correlation between the expression of cyclooxygenase-2 and E-cadherin in human bladder transitional cell carcinomas. Virchows Arch 457: 319-328, 2010.
17. Pryczynicz A, Guzińska-Ustymowicz K, Kemona A and Czyzewska J: Expression of the E-cadherin-catenin complex in patients with pancreatic ductal adenocarcinoma. Folia Histochem Cytobiol 48: 128-133, 2010.
18. Chung Y, Lam AK, Luk JM, Law S, Chan KW, Lee PY and Wong J: Altered E-cadherin expression and p120 catenin localization in esophageal squamous cell carcinoma. Ann Surg Oncol 14: 3260-3267, 2007. (Pubitemid 47594279)
19. Goodison S, Urquidi V and Tarin D: CD44 cell adhesion molecules. Mol Pathol 52: 189-196, 1999. (Pubitemid 29369203)
20. Yu P, Zhou L, Ke W and Li K: Clinical significance of pAKT and CD44v6 overexpression with breast cancer. J Cancer Res Clin Oncol 136: 1283-1292, 2010.
21. Zhou DH, Ma ZM and Chen Y: Expression and clinical significance of CD44v6 and sCD44v6 in gastric carcinoma. Zhonghua Zhong Liu Za Zhi (in Chinese) 29: 833-837, 2007.
22. Li DM, Li SS, Zhang YH, Zhang HJ, Gao DL and Wang YX: Expression of human chorionic gonadotropin, CD44v6 and CD44v4/5 in esophageal squamous cell carcinoma. World J Gastroenterol 11: 7401-7404, 2005.