A new assay for CCR5del32 mutation: Genotyping through the number of fragments amplified

Journal of Biomedical Nanotechnology

Volumn 7, Issue 6, 2011, Pages 754-758

  Wang, Qinglin ^a   Xiao, Li ^a   Zhang, Jia ^a   He, Nongyue ^b   Lu, Xueguan ^a   Li, Ping ^c   Li, Kai ^a  

^a SOOCHOW UNIVERSITY   (China)

^b SOUTHEAST UNIVERSITY   (China)

^c Hospital of Infectious Diseases of Jiang Su Province   (China)

Author keywords

CCR5del32; Deletion; HIV 1; Number of fragments

Indexed keywords

CCR5DEL32; DELETION; EPIDEMIOLOGICAL STUDIES; GENETIC ANALYSIS; GENOTYPING; HIV-1; HIV-1 INFECTIONS; NATURAL MUTANTS; NUMBER OF FRAGMENTS; PRIMER EXTENSION; STEM CELL TRANSPLANTATION;

BIOTECHNOLOGY; NANOTECHNOLOGY;

STEM CELLS;

CHEMOKINE RECEPTOR CCR5; PRIMER DNA;

AMPLIFIED FRAGMENT LENGTH POLYMORPHISM; ARTICLE; DNA TEMPLATE; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENOTYPE; HUMAN; HUMAN EXPERIMENT; SCREENING TEST;

BASE SEQUENCE; GENOTYPE; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, CCR5; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION;

EID: 84863020187     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2011.1345     Document Type: Article

References (19)

1. L. L. Chen, J. Zhang, H. L. Gao, D. F. Liao, and K. Li, The relationship between CCR5 and HIV-1 disease. J. University of South China (Medical Edition) 33, 166 (2005).
2. K. Allers, G. Hutter, J. Hofmann, C. Loddenkemper, K. Rieger, E. Thiel, and T. Schneider, Evidence for the cure of HIV infection by CCR5Δ32/ Δ32 stem cell transplantation. Blood 117, 279 (2011).
3. R. J. Landovitz and J. S. Currier, Clinical practice. Postexposure prophylaxis for HIV infection. N. Engl. J. Med. 18, 1768 (2009).
4. J. Zhang, C.L. Zhou, Y. F. Yin, L. L. Chen, J. R. Pardinas, T. T. Liu, H. L. Gao, J. S. Saladivar, and K. Li, Detection of known mutations with DNA polymerases: Its pharmacogenetic applications. Curr. Pharmacogenomics 4, 121 (2006).
5. K. Li, J. Zhang, L. Xiao, and P. Sirois, Gene therapy: Hope for HIV infection cure. Blood e-letter 1, 26 (2011).
6. J. Zhang, Y. O. Wu, L. Xiao, K. Li, L. L. Chen, and P. Sirois, Therapeutic potential of RNA interference against cellular targets of HIV infection. Mol. Biotechnol. 37, 225 (2007).
7. N. Holt, J. Wang, K. Kim, G. Friedman, X. Wang, V. Taupin, G. M. Crooks, D. B. Kohn, P. D. Gregory, M. C. Holmes, and P. M. Cannon, Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo. Nat. Biotechnol. 28, 839 (2010).
8. J. P. Ioannidis, P. S. Rosenberg, J. J. Goedert, L. J. Ashton, T. L. Benfield, S. P. Buchbinder, R. A. Coutinho, J. Eugen-Olsen, T. Gallart, T. L. Katzenstein, L. G. Kostrikis, H. Kuipers, L. G. Louie, S. A. Mallal, J. B. Margolick, O. P. Martinez, L. Meyer, N. L. Michael, E, Operskalski, G. pantaleo, G. P. Rizzardi, H. Schuitemaker, H. W. Sheppard, G. J. Stewart, I. D. Theodorou, H. Ullum, E. Vicenzi, D. Vlahov, D. Wilkinson, C. Workman, J. F. Zagury, and T. R. O'Brien, Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data. Ann. Intern. Med. 135, 782 (2001).
9. C. Barassi, A. Lazzarin, and L. Lopalco, CCR5-specific mucosal IgA in saliva and genital fluids of HIV-exposed seronegative subjects. Blood 104, 2205 (2004).
10. Y. Huang, W. A. Paxton, S. M. Wolinsky, A. U. Neumann, L. Zhang, T. He, S. Kang, D. Ceradini, Z. Jin, K. Yazdanbakhsh, K. Kunstman, D. Erickson, E. Dragon, N. R. Landau, J. Phair, D. D. Ho, and R. A. Koup, The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med. 2, 1240 (1996).
11. J. Zhang, B. Meng, D. Liao, L. Zhou, X. Zhang, L. Chen, Z. Guo, C. Peng, B. Zhu, P. P. Lee, X. Xu, T. Zhou, Z. Deng, Y. Hu, and K. Li, De novo synthesis of PCR templates for the development of SARS diagnostic assay. Mol. Biotechnol. 25, 107 (2003).
12. J. Zhang, L. Xiao, Y. F. Yin, P. Sirois, H. L. Gao, and K. Li, A law of mutation: Power Decay of small insertions and small deletions associated with human diseases. Appl. Biochem. Biotechnol. 162, 321 (2010).
13. H. Zhao, X. Ma, M. Li, D. Zhou, P. Xiao, and Z. Lu, Analysis of CpG island methylation using rolling circle amplification (RCA) product microarray. J. Biomed. Nanotechnol. 7, 292 (2011).
14. L. Cheng, Q. Ge, B. Sun, P. Yu, X. Ke, and Z. Lu, Polyacrylamide gel-based microarray: A novel method applied to the association study between the polymorphisms of BDNF gene and autism. J. Biomed. Nanotechnol. 5, 542 (2009).
15. L. Tian, S. Li, H. Liu, Z. Wang, and N. He, An automated magstation for high-throughput single nucleotide polymorphism genotyping and the dual-color hybridization. J. Biomed. Nanotechnol. 5, 511 (2009).
16. H. Liu, S. Li, L. Tian, L. Liu, and N. He, A novel single nucleotide polymorphisms detection sensors based on magnetic nanoparticles array and dual-color single base extension. J. Nanosci. Nanotechnol. 10, 5311 (2010).
17. H. Liu, S. Li, L. Liu, L. Tian, and N. He, An integrated and sensitive detection platform for biosensing application based on Fe@Au magnetic nanoparticles as bead array carries. Biosens. Bioelectron. 26, 1442 (2010).
18. H. Liu, S. Li, L. Liu, L. Tian, and N. He, Multiplex single nucleotide polymorphisms genotyping using solid-phase single base extension on magnetic nanoparticles. Anal. Biochem. 386, 126 (2009).
19. S. Li, H. Liu, L. Liu, L. Tian, and N. He, A novel automated assay with dual-color hybridization for single-nucleotide 4 polymorphisms genotyping on gold magnetic nanoparticle array. Anal. Biochem. 405, 141 (2010).