Preparation and preliminary biological evaluation of 177Lu- labeled GluDTPA-cyclo(RGDfK) for integrin αvβ3 receptor-positive tumor targeting

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 55, Issue 1, 2012, Pages 10-17

  Kim, Jin Hwan ^a   Lim, Jae Cheong ^b   Yun, Ki Cheol ^b   Choi, Sun Ju ^b   Hong, Young Don ^a,b  

^a Chonnam National University   (South Korea)

^b Korea Atomic Energy Research Institute   (South Korea)

Author keywords

angiogenesis; DTPA; integrin; RGD; tumor targeting

Indexed keywords

AMINO ACIDS; BLOOD; CELL PROLIFERATION; DIAGNOSIS; ENDOTHELIAL CELLS; PEPTIDES;

ANGIOGENESIS; BIOLOGICAL EVALUATION; DTPA; ENDOTHELIAL-CELLS; INTEGRINS; NON-INVASIVE IMAGING; RGD; RGD PEPTIDE; SOLID TUMORS; TUMOR-TARGETING;

TUMORS;

GLUTAMYLPENTETIC ACID CYCLO(ARGINYLGLYCYLASPARTIC ACID DEXTRO PHENYLALANYLLYSINE) LU 177; LUTETIUM 177; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG DISTRIBUTION; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; GLIOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOTOPE LABELING; MOUSE; NONHUMAN; RADIOCHEMISTRY; SOLID PHASE SYNTHESIS; TEMPERATURE; THIN LAYER CHROMATOGRAPHY; TUMOR DIAGNOSIS; TUMOR VOLUME;

MUS;

EID: 84863015346     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1944     Document Type: Article

References (40)

1. P. C. Brooks, R. A. Clark, D. A. Cheresh, Science 1994, 264, 569.
2. J. D. Hood, D. A. Cheresh, Nat. Rev. Cancer 2002, 2, 91.
3. Z. Liu, B. Jia, J. Shi, X. Jin, H. Zhao, F. Li, S. Liu, F. Wang, Bioconjug. Chem. 2010, 21, 548.
4. R. Haubner, H. J. Wester, F. Burkhart, R. Seekowitsch-Schmidtke, W. Weber, S. L. Goodman, H. Kessler, M. Schwaiger, J. Nucl. Med. 2001, 42, 326.
5. R. Haubner, H. J. Wester, W. Weber, C. Mang, S. I. Ziegler, S. L. Goodman, R. Seekowitsch-Schmidtke, H. Kessler, M. Schwaiger, Cancer Res. 2001, 61, 1781.
6. X. Chen, Mini Rev. Med. Chem. 2006, 6, 227.
7. S. Liu, Mol. Pharm. 2006, 3, 472.
8. A. J. Beer, M. Schwaiger, Cancer Metastasis Rev. 2008, 27, 631.
9. I. Dijkgraaf, J. A. Kruijtzer, S. Liu, A. C. Soede, W. J. Oyen, F. H. Corstens, R. M. Liskamp, O. C. Boerman, Eur. J. Nucl. Med. Mol. Imaging 2007, 34, 267.
10. I. Dijkgraaf, A. J. Beer, H. J. Wester, Front. Biosci. 2009, 14, 887.
11. A. J. Beer, A. L. Grosu, J. Carlsen, A. Kolk, M. Sarbia, I. Stangier, P. Watzlowik, H. J. Wester, R. Haubner, M. Schwaiger, Clin. Cancer Res. 2007, 13, 6610.
12. A. J. Beer, S. Lorenzen, S. Metz, K. Herrmann, P. Watzlowik, H. J. Wester, C. Peschel, F. Lordick, M. Schwaiger, J. Nucl. Med. 2008, 49, 22.
13. A. J. Beer, M. Niemeyer, J. Carlsen, M. Sarbia, J. Nahrig, P. Watzlowik, H. J. Wester, N. Harbeck, M. Schwaiger, J. Nucl. Med. 2008, 49, 255.
14. L. M. Kenny, R. C. Coombes, I. Oulie, K. B. Contractor, M. Miller, T. J. Spinks, B. McParland, P. S. Cohen, A. M. Hui, C. Palmieri, S. Osman, M. Glaser, D. Turton, A. Al-Nahhas, E. O. Aboagye, J. Nucl. Med. 2008, 49, 879.
15. D. R. K. A. Mohan, Q. Y. Jian, J. Nucl. Med. 2009, 50 (Supplement 2), 447.
16. O. Schnell, B. Krebs, J. Carlsen, I. Miederer, C. Goetz, R. H. Goldbrunner, H. J. Wester, R. Haubner, G. Popperl, M. Holtmannspotter, H. A. Kretzschmar, H. Kessler, J. C. Tonn, M. Schwaiger, A. J. Beer, Neuro Oncol. 2009, 11, 861.
17. S. Mundwiler, R. Waibel, B. Spingler, S. Kunze, R. Alberto, Nucl. Med. Biol. 2005, 32, 473.
18. R. Schibli, P. A. Schubiger, Eur. J. Nucl. Med. Mol. Imaging 2002, 29, 1529.
19. K. H. Choi, Y. D. Hong, M. S. Pyun, S. J. Choi, Bull. Korean. Chem. Soc. 2006, 27, 1194.
20. W. A. P. Breeman, M. de Jong, D. J. Kwekkeboom, R. Valkema, W. H. Bakker, P. P. M. Kooij, T. J. Visser, E. P. Krenning, Eur. J. Nucl. Med. 2001, 28, 1421.
21. S. Y. Lee, Y. D. Hong, P. M. Felipe, M. S. Pyun, S. J. Choi, Appl. Radiat. Isot. 2009, 67, 1366.
22. M. S. Pyun, K. H. Choi, Y. D. Hong, S. J. Choi, Bull. Korean. Chem. Soc. 2009, 30, 1187.
23. F. F. Anelli, O. Gazzotti, L. Lattauada, G. Lux, F. Rebasti, Bioconjug. Chem. 1999, 10, 137.
24. S. Chakraborty, J. Shi, Y. S. Kim, Y. Zhou, B. Jia, F. Wang, S. Liu, Bioconjug. Chem. 2010, 21, 969.
25. R. O. Hynes, Cell 1992, 69, 11.
26. R. E. Seftor, E. A. Seftor, K. R. Gehlsen, W. G. Stetler-Stevenson, P. D. Brown, E. Ruoslahti, M. J. Hendrix, Proc. Natl. Acad. Sci. 1992, 89, 1557.
27. J. R. Hart, Ethylenediaminetetraacetic acid and related chelating agents. In Ullmann's Encyclopedia of Industrial Chemistry Wiley-VCH, Weinheim, 2005.
28. M. K. Dewanjee, D. J. Hnatowich, R. Beh, J. Nucl. Med. 1976, 17, 1003.
29. B. Maziere, O. Stulzaft, J. M. Verret, D. Comar, A. Syrota, Int. J. Appl. Radiat. Isot. 1983, 34, 595.
30. C. J. Anderson, P. A. Rocque, C. J. Weinheimer, M. J. Welch, Nucl. Med. Biol. 1993, 20, 461.
31. Y. D. Hong, K. B. Park, B. S. Jang, S. J. Choi, S. M. Choi, Y. M. Kim, Nucl. Med. Biol. 2002, 29, 833.
32. L. Correa-Gonzalez, C. Arteaga de Murphy, G. Ferro-Flores, M. Pedraza-Lopez, E. Murphy-Stack, D. Mino-Leon, G. Perez-Villasenor, Y. Diaz-Torres, R. Munoz-Olvera, Nucl. Med. Biol. 2003, 30, 135.
33. M. P. Kelly, F. T. Lee, K. Tahtis, F. E. Smyth, M. W. Brechbiel, A. M. Scott, Clin. Cancer Res. 2007, 13, 5604s.
34. S. Shanehsazzadeh, A. R. Jalilian, H. R. Sadeghi, M. Allahverdi, Radiat. Prot. Dosimetry 2009, 134, 79.
35. A. Yurt, F. Z. Muftuler, P. Unak, S. Yolcular, C. Acar, H. Enginar, Cancer Biother. Radiopharm. 2009, 24, 707.
36. Y. Chen, Q. F. Xiong, X. Q. Yang, L. He, Z. W. Huang, Am. J. Roentgenol. 2010, 194, 761.
37. P. A. Erba, A. G. Cataldi, C. Tascini, A. Leonildi, C. Manfredi, G. Mariani, E. Lazzeri, Nucl. Med. Commun. 2010, 31, 994.
38. J. Shi, Z. Liu, B. Jia, Z. Yu, H. Zhao, F. Wang, Amino Acids 2010, 39, 111.
39. M. Janssen, W. J. Oyen, L. F. Massuger, C. Frielink, I. Dijkgraaf, D. S. Edwards, M. Radjopadhye, F. H. Corstens, O. C. Boerman, Cancer Biother. Radiopharm. 2002, 17, 641.
40. G. Thumshirn, U. Hersel, S. L. Goodman, H. Kessler, Chemistry 2003, 9, 2717.