Protective efficacy of a treponema pallidum gpd dna vaccine vectored by chitosan nanoparticles and fused with interleukin-2

Canadian Journal of Microbiology

Volumn 58, Issue 2, 2012, Pages 117-123

  Zhao, Feijun ^a,b   Wang, Shiping ^b   Zhang, Xiaohong ^a   Gu, Weiming ^c   Yu, Jian ^a   Liu, Shuangquan ^a   Zeng, Tiebing ^a   Zhang, Yuejun ^a   Wu, Yimou ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b Central South University   (China)

^c Skin Diseases and STD Hospital   (China)

Author keywords

Chitosan; Gpd; Il 2; Membrane protein; Nucleic acid vaccine; Treponema pallidum

Indexed keywords

CHITOSAN NANOPARTICLES; DARK FIELD; DNA VACCINE; GPD; IL-2; IMMUNE RESPONSE; INTERLEUKIN-2; MEMBRANE PROTEIN; NEW ZEALAND WHITE RABBIT; PHOSPHODIESTERASES; PROTECTIVE EFFICACY; TREPONEMA PALLIDUM;

BACTERIA; BIOLOGICAL MEMBRANES; CHITOSAN; DNA; ENZYME INHIBITION; NANOPARTICLES;

VACCINES;

BACTERIAL ENZYME; CHITOSAN; CYTOKINE; DNA VACCINE; GAMMA INTERFERON; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE INTERLEUKIN 2 FUSION DNA VACCINE; INTERLEUKIN 2; NANOPARTICLE; TREPONEMA PALLIDUM GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DNA VACCINE; UNCLASSIFIED DRUG;

ANTIBODY; ANTIGEN; BACTERIUM; BIOTECHNOLOGY; CHITIN; DISEASE CONTROL; EFFICIENCY MEASUREMENT; ENZYME ACTIVITY; IMMUNE RESPONSE; IMMUNIZATION; LAGOMORPH; LESION; MEDICINE; NUCLEIC ACID; PROTEIN; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL RABBIT; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNIZATION; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SPIROCHETE; SPIROCHETE INFECTION; SPLEEN CELL; SPLEEN LYMPHOCYTE; SYPHILIS; TH1 CELL; TREPONEMA PALLIDUM; TREPONEMATOSIS; ULCER;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GENETIC VECTORS; HUMANS; IMMUNIZATION; INTERFERON-GAMMA; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MALE; NANOPARTICLES; RABBITS; SYPHILIS; TREPONEMA PALLIDUM; VACCINES, DNA;

ORYCTOLAGUS CUNICULUS; SPIROCHAETALES; TREPONEMA PALLIDUM;

EID: 84863011595     PISSN: 00084166     EISSN: 14803275     Source Type: Journal    
DOI: 10.1139/W11-115     Document Type: Article

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