RTMS with motor training modulates cortico-basal ganglia-thalamocortical circuits in stroke patients

Restorative Neurology and Neuroscience

Volumn 30, Issue 3, 2012, Pages 179-189

  Chang, Won Hyuk ^a   Kim, Yun Hee ^a   Yoo, Woo Kyoung ^b   Goo, Kyoung Hyup ^a   Park, Chang Hyun ^a   Kim, Sung Tae ^a   Pascual Leone, Alvaro ^c  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Hallym University   (South Korea)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

cortico basal ganglia thalamocortical circuits; functional MRI; motor function; repetitive transcranial magnetic stimulation; Stroke

Indexed keywords

ADULT; AGED; ARTICLE; CAUDATE NUCLEUS; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEMIPARESIS; HEMISPHERE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTOR PERFORMANCE; MUSCLE TRAINING; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; STROKE; THALAMUS; TRANSCRANIAL MAGNETIC STIMULATION;

AGED; EXERCISE THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; NEURAL PATHWAYS; PARESIS; PHYSICAL THERAPY MODALITIES; SINGLE-BLIND METHOD; STROKE; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 84863001198     PISSN: 09226028     EISSN: 18783627     Source Type: Journal    
DOI: 10.3233/RNN-2012-110162     Document Type: Article

References (29)

1. Ackerley, S.J., Stinear, C.M., Barber, P.A. & Byblow, W.D. (2010). Combining theta burst stimulation with training after subcortical stroke. Stroke, 41(7), 1568-1572.
2. Bestmann, S., Baudewig, J., Siebner, H.R., Rothwell, J.C. & Frahm, J. (2004). Functional MRI of the immediate impact of transcranial magnetic stimulation on cortical and subcortical motor circuits. Eur J Neurosci, 19(7), 1950-1962.
3. Bestmann, S., Baudewig, J., Siebner, H.R., Rothwell, J.C. & Frahm, J. (2005). BOLD MRI responses to repetitive TMS over human dorsal premotor cortex. Neuroimage, 28(1), 22-29.
4. Bland, M. (2000). An introduction to medical statistics, 3rd ed., Oxford University Press, Oxford.
5. Brasil-Neto, J.P., Cohen, L.G., Panizza, M., Nilsson, J., Roth, B.J. & Hallett, M. (1992). Optimal focal transcranial magnetic activation of the human motor cortex: Effects of coil orientation, shape of the induced current pulse, and stimulus intensity. J Clin Neurophysiol, 9(1), 132-136.
6. Fitzgerald, P.B., Fountain, S. & Daskalakis, Z.J. (2006). A comprehensive review of the effects of rTMS on motor cortical excitability and inhibition. Clin Neurophysiol, 117(12), 2584-2596.
7. Friston, K.J., Holmes, A.P., Poline, J.B., Grasby, P.J.,Williams, S.C., Frackowiak, R.S. & Turner, R. (1995). Analysis of fMRI timeseries revisited. Neuroimage, 2(1), 45-53.
8. Hackel, M.E., Wolfe, G.A., Bang, S.M. & Canfield, J.S. (1992). Changes in hand function in the aging adult as determined by the Jebsen test of hand function. Phys Ther, 72(5), 373-377.
9. Holler, I., Siebner, H.R., Cunnington, R. & Gerschlager,W. (2006). 5Hz repetitive TMS increases anticipatory motor activity in the human cortex. Neurosci Lett, 392(3), 221-225.
10. Jebsen, R.H.,Taylor, N.,Trieschmann, R.B.,Trotter,M.J. & Howard, L.A. (1969). An objective and standardized test of hand function. Arch Phys Med Rehabil, 50(6), 311-319.
11. Johansen-Berg, H., Dawes, H., Guy, C., Smith, S.M.,Wade, D.T. & Matthews, P.M. (2002). Correlation between motor improvements and altered fMRI activity after rehabilitative therapy. Brain, 125(Pt 12), 2731-2742.
12. Khedr, E.M., Kotb, H., Kamel, N.F., Ahmed, M.A., Sadek, R. & Rothwell, J.C. (2005). Longlasting antalgic effects of daily sessions of repetitive transcranial magnetic stimulation in central and peripheral neuropathic pain. J Neurol Neurosurg Psychiatry, 76(6), 833-838.
13. Kim, Y.H., Park, J.W., Ko, M.H., Jang, S.H. & Lee, P.K. (2004). Facilitative effect of high frequency subthreshold repetitive transcranial magnetic stimulation on complex sequential motor learning in humans. Neurosci Lett, 367(2), 181-185.
14. Kim, Y.H., You, S.H., Ko, M.H., Park, J.W., Lee, K.H., Jang, S.H., Yoo, W.K. & Hallett, M. (2006). Repetitive transcranial magnetic stimulation-induced corticomotor excitability and associated motor skill acquisition in chronic stroke. Stroke, 37(6), 1471-1476.
15. Pascual-Leone, A., Valls-Sole, J., Brasil-Neto, J.P., Cohen, L.G. & Hallett, M. (1994). Akinesia in Parkinson's disease. I. Shortening of simple reaction time with focal, single-pulse transcranial magnetic stimulation. Neurology, 44(5), 884-891.
16. Rossini, P.M., Barker, A.T., Berardelli, A., Caramia, M.D., Caruso, G., Cracco, R.Q., Dimitrijevic, M.R., Hallett, M., Katayama, Y., Lucking, C.H., et al. (1994). Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: Basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol, 91(2), 79-92.
17. Siebner, H.R., Mentschel, C., Auer, C. & Conrad, B. (1999). Repetitive transcranial magnetic stimulation has a beneficial effect on bradykinesia in Parkinson's disease. Neuroreport, 10(3), 589-594.
18. Siebner, H.R., Peller, M., Willoch, F., Minoshima, S., Boecker, H., Auer, C., Drzezga, A., Conrad, B. & Bartenstein, P. (2000). Lasting cortical activation after repetitive TMS of the motor cortex: A glucose metabolic study. Neurology, 54(4), 956-963.
19. Strafella, A.P., Paus, T., Barrett, J. & Dagher, A. (2001). Repetitive transcranial magnetic stimulation of the human prefrontal cortex induces dopamine release in the caudate nucleus. J Neurosci, 21(15), RC157.
20. Strafella, A.P., Paus, T., Fraraccio, M. & Dagher, A. (2003). Striatal dopamine release induced by repetitive transcranial magnetic stimulation of the human motor cortex. Brain, 126(Pt 12), 2609-2615.
21. Takeuchi, N., Chuma, T., Matsuo, Y., Watanabe, I. & Ikoma, K. (2005). Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke. Stroke, 36(12), 2681-2686.
22. Takeuchi, N., Tada, T., Toshima, M., Matsuo, Y. & Ikoma, K. (2009). Repetitive transcranial magnetic stimulation over bilateral hemispheres enhances motor function and training effect of paretic hand in patients after stroke. J Rehabil Med, 41(13), 1049-1054.
23. Talelli, P., Greenwood, R.J. & Rothwell, J.C. (2007). Exploring theta burst stimulation as an intervention to improve motor recovery in chronic stroke. Clin Neurophysiol, 118(2), 333-342.
24. Uy, J., Ridding, M.C. & Miles, T.S. (2002). Stability of maps of human motor cortex made with transcranial magnetic stimulation. Brain Topogr, 14(4), 293-297.
25. Ward, N.S., Brown, M.M., Thompson, A.J. & Frackowiak, R.S. (2003). Neural correlates of motor recovery after stroke: A longitudinal fMRI study. Brain, 126(Pt 11), 2476-2496.
26. Ward, N.S., Newton, J.M., Swayne, O.B., Lee, L., Frackowiak, R.S., Thompson, A.J., Greenwood, R.J. & Rothwell, J.C. (2007). The relationship between brain activity and peak grip force is modulated by corticospinal system integrity after subcortical stroke. Eur J Neurosci, 25(6), 1865-1873.
27. Wassermann, E.M., Grafman, J., Berry, C., Hollnagel, C., Wild, K., Clark, K. & Hallett, M. (1996). Use and safety of a new repetitive transcranial magnetic stimulator. Electroencephalogr Clin Neurophysiol, 101(5), 412-417.
28. Wickens, J.R., Reynolds, J.N. & Hyland, B.I. (2003). Neural mechanisms of reward-related motor learning. Curr Opin Neurobiol, 13(6), 685-690.
29. Yoo,W.K., You, S.H., Ko,M.H., Tae Kim, S., Park, C.H., Park, J.W., Hoon Ohn, S., Hallett, M. & Kim, Y.H. (2008). High frequency rTMS modulation of the sensorimotor networks: Behavioral changes and fMRI correlates. Neuroimage, 39(4), 1886-1895.