메뉴 건너뛰기




Volumn 7, Issue 6, 2012, Pages

Myoferlin depletion in breast cancer cells promotes mesenchymal to epithelial shape change and stalls invasion

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; MATRIX METALLOPROTEINASE; MEMBRANE PROTEIN; MYOFERLIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

EID: 84862996842     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039766     Document Type: Article
Times cited : (43)

References (54)
  • 1
    • 77950597484 scopus 로고    scopus 로고
    • Breast Cancer Facts & Figures 2009-2010
    • American Cancer Society
    • American Cancer Society (2009) Breast Cancer Facts & Figures 2009-2010.
    • (2009)
  • 2
    • 67650584040 scopus 로고    scopus 로고
    • Available, National Cancer Institute. National Cancer Institute Surveillance Epidemiology and End Results website
    • Horner MRL, Krapcho M, Neyman N, Aminou R, Howlader N, et al. (2009) SEER Cancer Statistics Review, 1975-2006. National Cancer Institute. National Cancer Institute Surveillance Epidemiology and End Results website. Available:http://seer.cancer.gov/csr/1975_2006/. Accessed 2012 Jan 12.
    • (2009) SEER Cancer Statistics Review, 1975-2006
    • Horner, M.R.L.1    Krapcho, M.2    Neyman, N.3    Aminou, R.4    Howlader, N.5
  • 3
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA, (2000) The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA, (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA, (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 6
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer CL, Weinberg RA, (2011) A perspective on cancer cell metastasis. Science 331: 1559-1564.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 7
    • 65249155429 scopus 로고    scopus 로고
    • Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited
    • Sabeh F, Shimizu-Hirota R, Weiss SJ, (2009) Protease-dependent versus-independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J Cell Biol 185: 11-19.
    • (2009) J Cell Biol , vol.185 , pp. 11-19
    • Sabeh, F.1    Shimizu-Hirota, R.2    Weiss, S.J.3
  • 8
    • 77952902430 scopus 로고    scopus 로고
    • Mechanisms of motility in metastasizing cells
    • Yilmaz M, Christofori G, (2010) Mechanisms of motility in metastasizing cells. Mol Cancer Res 8: 629-642.
    • (2010) Mol Cancer Res , vol.8 , pp. 629-642
    • Yilmaz, M.1    Christofori, G.2
  • 9
    • 70350142558 scopus 로고    scopus 로고
    • The role of vesicle trafficking in epithelial cell motility
    • Fletcher SJ, Rappoport JZ, (2009) The role of vesicle trafficking in epithelial cell motility. Biochem Soc Trans 37: 1072-1076.
    • (2009) Biochem Soc Trans , vol.37 , pp. 1072-1076
    • Fletcher, S.J.1    Rappoport, J.Z.2
  • 10
    • 44649198353 scopus 로고    scopus 로고
    • Endocytic transport of integrins during cell migration and invasion
    • Caswell P, Norman J, (2008) Endocytic transport of integrins during cell migration and invasion. Trends Cell Biol 18: 257-263.
    • (2008) Trends Cell Biol , vol.18 , pp. 257-263
    • Caswell, P.1    Norman, J.2
  • 11
    • 68849092564 scopus 로고    scopus 로고
    • Genomic amplicons target vesicle recycling in breast cancer
    • Mills GB, Jurisica I, Yarden Y, Norman JC, (2009) Genomic amplicons target vesicle recycling in breast cancer. J Clin Invest 119: 2123-2127.
    • (2009) J Clin Invest , vol.119 , pp. 2123-2127
    • Mills, G.B.1    Jurisica, I.2    Yarden, Y.3    Norman, J.C.4
  • 12
    • 79151485206 scopus 로고    scopus 로고
    • Secretory and endo/exocytic trafficking in invadopodia formation: the MT1-MMP paradigm
    • Frittoli E, Palamidessi A, Disanza A, Scita G, (2011) Secretory and endo/exocytic trafficking in invadopodia formation: the MT1-MMP paradigm. Eur J Cell Biol 90: 108-114.
    • (2011) Eur J Cell Biol , vol.90 , pp. 108-114
    • Frittoli, E.1    Palamidessi, A.2    Disanza, A.3    Scita, G.4
  • 13
    • 75449112263 scopus 로고    scopus 로고
    • Aiming for invadopodia: organizing polarized delivery at sites of invasion
    • Caldieri G, Buccione R, (2010) Aiming for invadopodia: organizing polarized delivery at sites of invasion. Trends Cell Biol 20: 64-70.
    • (2010) Trends Cell Biol , vol.20 , pp. 64-70
    • Caldieri, G.1    Buccione, R.2
  • 14
    • 77955001359 scopus 로고    scopus 로고
    • Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins
    • Lek A, Lek M, North KN, Cooper ST, (2010) Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins. BMC Evol Biol 10: 231.
    • (2010) BMC Evol Biol , vol.10 , pp. 231
    • Lek, A.1    Lek, M.2    North, K.N.3    Cooper, S.T.4
  • 15
    • 33746054560 scopus 로고    scopus 로고
    • FER-1 regulates Ca2+ -mediated membrane fusion during C. elegans spermatogenesis
    • Washington NL, Ward S, (2006) FER-1 regulates Ca2+-mediated membrane fusion during C. elegans spermatogenesis. J Cell Sci 119: 2552-2562.
    • (2006) J Cell Sci , vol.119 , pp. 2552-2562
    • Washington, N.L.1    Ward, S.2
  • 16
    • 17344365600 scopus 로고    scopus 로고
    • Dysferlin, a novel skeletal muscle gene, is mutated in Miyoshi myopathy and limb girdle muscular dystrophy
    • Liu J, Aoki M, Illa I, Wu C, Fardeau M, et al. (1998) Dysferlin, a novel skeletal muscle gene, is mutated in Miyoshi myopathy and limb girdle muscular dystrophy. Nat Genet 20: 31-36.
    • (1998) Nat Genet , vol.20 , pp. 31-36
    • Liu, J.1    Aoki, M.2    Illa, I.3    Wu, C.4    Fardeau, M.5
  • 17
    • 0347379869 scopus 로고    scopus 로고
    • Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing
    • Lennon NJ, Kho A, Bacskai BJ, Perlmutter SL, Hyman BT, et al. (2003) Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing. J Biol Chem 278: 50466-50473.
    • (2003) J Biol Chem , vol.278 , pp. 50466-50473
    • Lennon, N.J.1    Kho, A.2    Bacskai, B.J.3    Perlmutter, S.L.4    Hyman, B.T.5
  • 18
    • 1842556210 scopus 로고    scopus 로고
    • Dysferlin and the plasma membrane repair in muscular dystrophy
    • Bansal D, Campbell KP, (2004) Dysferlin and the plasma membrane repair in muscular dystrophy. Trends Cell Biol 14: 206-213.
    • (2004) Trends Cell Biol , vol.14 , pp. 206-213
    • Bansal, D.1    Campbell, K.P.2
  • 19
    • 34548009359 scopus 로고    scopus 로고
    • Dysferlin and muscle membrane repair
    • Han R, Campbell KP, (2007) Dysferlin and muscle membrane repair. Curr Opin Cell Biol 19: 409-416.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 409-416
    • Han, R.1    Campbell, K.P.2
  • 20
    • 0033846745 scopus 로고    scopus 로고
    • OTOF encodes multiple long and short isoforms: genetic evidence that the long ones underlie recessive deafness DFNB9
    • Yasunaga S, Grati M, Chardenoux S, Smith TN, Friedman TB, et al. (2000) OTOF encodes multiple long and short isoforms: genetic evidence that the long ones underlie recessive deafness DFNB9. Am J Hum Genet 67: 591-600.
    • (2000) Am J Hum Genet , vol.67 , pp. 591-600
    • Yasunaga, S.1    Grati, M.2    Chardenoux, S.3    Smith, T.N.4    Friedman, T.B.5
  • 21
    • 33749994043 scopus 로고    scopus 로고
    • Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse
    • Roux I, Safieddine S, Nouvian R, Grati M, Simmler MC, et al. (2006) Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell 127: 277-289.
    • (2006) Cell , vol.127 , pp. 277-289
    • Roux, I.1    Safieddine, S.2    Nouvian, R.3    Grati, M.4    Simmler, M.C.5
  • 24
    • 35648929848 scopus 로고    scopus 로고
    • Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function
    • Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, et al. (2007) Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function. J Biol Chem 282: 30745-30753.
    • (2007) J Biol Chem , vol.282 , pp. 30745-30753
    • Bernatchez, P.N.1    Acevedo, L.2    Fernandez-Hernando, C.3    Murata, T.4    Chalouni, C.5
  • 25
    • 80051794800 scopus 로고    scopus 로고
    • Myoferlin gene silencing decreases Tie-2 expression in vitro and angiogenesis in vivo
    • Yu C, Sharma A, Trane A, Utokaparch S, Leung C, et al. (2011) Myoferlin gene silencing decreases Tie-2 expression in vitro and angiogenesis in vivo. Vascul Pharmacol.
    • (2011) Vascul Pharmacol
    • Yu, C.1    Sharma, A.2    Trane, A.3    Utokaparch, S.4    Leung, C.5
  • 26
    • 77951640392 scopus 로고    scopus 로고
    • Myoferlin is required for insulin-like growth factor response and muscle growth
    • Demonbreun AR, Posey AD, Heretis K, Swaggart KA, Earley JU, et al. (2010) Myoferlin is required for insulin-like growth factor response and muscle growth. FASEB J 24: 1284-1295.
    • (2010) FASEB J , vol.24 , pp. 1284-1295
    • Demonbreun, A.R.1    Posey, A.D.2    Heretis, K.3    Swaggart, K.A.4    Earley, J.U.5
  • 27
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • van 't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3    He, Y.D.4    Hart, A.A.5
  • 28
    • 10744219705 scopus 로고    scopus 로고
    • Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes
    • Amatschek S, Koenig U, Auer H, Steinlein P, Pacher M, et al. (2004) Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes. Cancer Res 64: 844-856.
    • (2004) Cancer Res , vol.64 , pp. 844-856
    • Amatschek, S.1    Koenig, U.2    Auer, H.3    Steinlein, P.4    Pacher, M.5
  • 29
    • 0037458636 scopus 로고    scopus 로고
    • Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer
    • Adam PJ, Boyd R, Tyson KL, Fletcher GC, Stamps A, et al. (2003) Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. J Biol Chem 278: 6482-6489.
    • (2003) J Biol Chem , vol.278 , pp. 6482-6489
    • Adam, P.J.1    Boyd, R.2    Tyson, K.L.3    Fletcher, G.C.4    Stamps, A.5
  • 31
    • 34848826864 scopus 로고    scopus 로고
    • Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression
    • Hugo H, Ackland ML, Blick T, Lawrence MG, Clements JA, et al. (2007) Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression. J Cell Physiol 213: 374-383.
    • (2007) J Cell Physiol , vol.213 , pp. 374-383
    • Hugo, H.1    Ackland, M.L.2    Blick, T.3    Lawrence, M.G.4    Clements, J.A.5
  • 32
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • Soule HD, Maloney TM, Wolman SR, Peterson WD Jr, Brenz R, et al. (1990) Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res 50: 6075-6086.
    • (1990) Cancer Res , vol.50 , pp. 6075-6086
    • Soule, H.D.1    Maloney, T.M.2    Wolman, S.R.3    Peterson Jr., W.D.4    Brenz, R.5
  • 33
    • 0026518636 scopus 로고
    • Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines
    • Thompson EW, Paik S, Brunner N, Sommers CL, Zugmaier G, et al. (1992) Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 150: 534-544.
    • (1992) J Cell Physiol , vol.150 , pp. 534-544
    • Thompson, E.W.1    Paik, S.2    Brunner, N.3    Sommers, C.L.4    Zugmaier, G.5
  • 34
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10: 515-527.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5
  • 35
    • 58149204055 scopus 로고    scopus 로고
    • ArrayExpress update-from an archive of functional genomics experiments to the atlas of gene expression
    • Parkinson H, Kapushesky M, Kolesnikov N, Rustici G, Shojatalab M, et al. (2009) ArrayExpress update-from an archive of functional genomics experiments to the atlas of gene expression. Nucleic Acids Res 37: D868-D872.
    • (2009) Nucleic Acids Res , vol.37
    • Parkinson, H.1    Kapushesky, M.2    Kolesnikov, N.3    Rustici, G.4    Shojatalab, M.5
  • 36
    • 40949157661 scopus 로고    scopus 로고
    • Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome
    • Cheng AS, Culhane AC, Chan MW, Venkataramu CR, Ehrich M, et al. (2008) Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Res 68: 1786-1796.
    • (2008) Cancer Res , vol.68 , pp. 1786-1796
    • Cheng, A.S.1    Culhane, A.C.2    Chan, M.W.3    Venkataramu, C.R.4    Ehrich, M.5
  • 37
    • 70349238666 scopus 로고    scopus 로고
    • Molecular bandages: inside-out, outside-in repair of cellular membranes. Focus on "Myoferlin is critical for endocytosis in endothelial cells"
    • Cipta S, Patel HH, (2009) Molecular bandages: inside-out, outside-in repair of cellular membranes. Focus on "Myoferlin is critical for endocytosis in endothelial cells". Am J Physiol Cell Physiol 297: C481-C483.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • Cipta, S.1    Patel, H.H.2
  • 40
    • 0026701412 scopus 로고
    • Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components
    • Vukicevic S, Kleinman HK, Luyten FP, Roberts AB, Roche NS, et al. (1992) Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components. Exp Cell Res 202: 1-8.
    • (1992) Exp Cell Res , vol.202 , pp. 1-8
    • Vukicevic, S.1    Kleinman, H.K.2    Luyten, F.P.3    Roberts, A.B.4    Roche, N.S.5
  • 41
    • 74049124186 scopus 로고    scopus 로고
    • Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
    • Jackson AL, Linsley PS, (2010) Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat Rev Drug Discov 9: 57-67.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 57-67
    • Jackson, A.L.1    Linsley, P.S.2
  • 42
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
    • Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3    Zhang, J.4    Zhang, Z.5
  • 43
    • 33749059160 scopus 로고    scopus 로고
    • miRBase: the microRNA sequence database
    • Griffiths-Jones S, (2006) miRBase: the microRNA sequence database. Methods Mol Biol 342: 129-138.
    • (2006) Methods Mol Biol , vol.342 , pp. 129-138
    • Griffiths-Jones, S.1
  • 44
    • 0019067646 scopus 로고
    • Caenorhabditis elegans fertilization-defective mutants with abnormal sperm
    • Argon Y, Ward S, (1980) Caenorhabditis elegans fertilization-defective mutants with abnormal sperm. Genetics 96: 413-433.
    • (1980) Genetics , vol.96 , pp. 413-433
    • Argon, Y.1    Ward, S.2
  • 45
    • 0030972880 scopus 로고    scopus 로고
    • A nematode gene required for sperm vesicle fusion
    • Achanzar WE, Ward S, (1997) A nematode gene required for sperm vesicle fusion. J Cell Sci 110 (Pt 9): 1073-1081.
    • (1997) J Cell Sci , vol.110 , Issue.Pt 9 , pp. 1073-1081
    • Achanzar, W.E.1    Ward, S.2
  • 46
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: building a framework
    • Gupta GP, Massague J, (2006) Cancer metastasis: building a framework. Cell 127: 679-695.
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 47
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA, (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 48
    • 68549130679 scopus 로고    scopus 로고
    • Proteolytic interstitial cell migration: a five-step process
    • Friedl P, Wolf K, (2009) Proteolytic interstitial cell migration: a five-step process. Cancer Metastasis Rev 28: 129-135.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 129-135
    • Friedl, P.1    Wolf, K.2
  • 49
    • 54049137191 scopus 로고    scopus 로고
    • Breaching the basement membrane: who, when and how?
    • Rowe RG, Weiss SJ, (2008) Breaching the basement membrane: who, when and how? Trends Cell Biol 18: 560-574.
    • (2008) Trends Cell Biol , vol.18 , pp. 560-574
    • Rowe, R.G.1    Weiss, S.J.2
  • 50
    • 70350233406 scopus 로고    scopus 로고
    • Navigating ECM barriers at the invasive front: the cancer cell-stroma interface
    • Rowe RG, Weiss SJ, (2009) Navigating ECM barriers at the invasive front: the cancer cell-stroma interface. Annu Rev Cell Dev Biol 25: 567-595.
    • (2009) Annu Rev Cell Dev Biol , vol.25 , pp. 567-595
    • Rowe, R.G.1    Weiss, S.J.2
  • 51
    • 78751683605 scopus 로고    scopus 로고
    • Impaired muscle growth and response to insulin-like growth factor 1 in dysferlin-mediated muscular dystrophy
    • Demonbreun AR, Fahrenbach JP, Deveaux K, Earley JU, Pytel P, et al. (2011) Impaired muscle growth and response to insulin-like growth factor 1 in dysferlin-mediated muscular dystrophy. Hum Mol Genet 20: 779-789.
    • (2011) Hum Mol Genet , vol.20 , pp. 779-789
    • Demonbreun, A.R.1    Fahrenbach, J.P.2    Deveaux, K.3    Earley, J.U.4    Pytel, P.5
  • 52
    • 78149284770 scopus 로고    scopus 로고
    • A new role for the muscle repair protein dysferlin in endothelial cell adhesion and angiogenesis
    • Sharma A, Yu C, Leung C, Trane A, Lau M, et al. (2010) A new role for the muscle repair protein dysferlin in endothelial cell adhesion and angiogenesis. Arterioscler Thromb Vasc Biol 30: 2196-2204.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2196-2204
    • Sharma, A.1    Yu, C.2    Leung, C.3    Trane, A.4    Lau, M.5
  • 53
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS, (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30: 256-268.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 54
    • 0036995757 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor-host cell communication
    • Lynch CC, Matrisian LM, (2002) Matrix metalloproteinases in tumor-host cell communication. Differentiation 70: 561-573.
    • (2002) Differentiation , vol.70 , pp. 561-573
    • Lynch, C.C.1    Matrisian, L.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.