Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 26, 2012, Pages 10310-10315

  Kowalewski, Björn ^a   Lamanna, William C ^b   Lawrence, Roger ^b   Damme, Markus ^a   Stroobants, Stijn ^c   Padva, Michael ^d   Kalus, Ina ^a   Frese, Marc André ^a   Lub̈ke, Torben ^a   Lul̈lmann Rauch, Renate ^e   D'Hooge, Rudi ^c   Esko, Jeffrey D ^b   Dierks, Thomas ^a  

^a BIELEFELD UNIVERSITY   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e UNIVERSITY OF KIEL   (Germany)

Author keywords

Lysosomes; Mouse model; Sanfilippo syndrome; Sulfatases

Indexed keywords

ARYLSULFATASE; GLUCOSAMINE DERIVATIVE; HEPARAN SULFATE; LYSOSOME ENZYME; RECOMBINANT ENZYME;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INACTIVATION; GLYCOSAMINOGLYCAN METABOLISM; MOUSE; MUCOPOLYSACCHARIDOSIS; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ARYLSULFATASES; BEHAVIOR, ANIMAL; MICE; MUCOPOLYSACCHARIDOSES; SULFATASES;

MUS;

EID: 84862987174     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202071109     Document Type: Article

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