Methylprednisolone induces apoptosis by interacting with the JAK/STAT pathway in HL-60 and K-562 leukemic cells

Hematology

Volumn 17, Issue 2, 2012, Pages 93-99

  Kaymaz, Burçin Tezcanli ^a   Selvi, Nur ^a   Saydam, Güray ^a   Şahin, Fahri ^a   Kosova, Buket ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

Apoptosis; JAK STAT pathway; Leukemia; Methylprednisolone

Indexed keywords

JANUS KINASE; LIPOCORTIN 5; MESSENGER RNA; METHYLPREDNISOLONE; STAT PROTEIN; STAT3 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL ASSAY; CELL DIFFERENTIATION; CELL STRAIN HL 60; CELL STRAIN K 562; CONTROLLED STUDY; DNA SEQUENCE; DOWN REGULATION; DRUG EFFECT; DRUG MEGADOSE; DRUG PROTEIN BINDING; FLUORESCENCE MICROSCOPY; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IC 50; INTRACELLULAR SIGNALING; LEUKEMIA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAT3 GENE; STAT5A GENE; STAT5B GENE; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; GENE EXPRESSION; GLUCOCORTICOIDS; HL-60 CELLS; HUMANS; K562 CELLS; METHYLPREDNISOLONE; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEINS;

EID: 84862980728     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453312X13221316477859     Document Type: Article

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