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Volumn 1 DEC, Issue , 2010, Pages

Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions

Author keywords

Afferent arteriole; Blood pressure; Epoxyeicosanoids; Hypertension; Vasodilation

Indexed keywords


EID: 84862963354     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2010.00157     Document Type: Article
Times cited : (50)

References (29)
  • 1
    • 0030051805 scopus 로고    scopus 로고
    • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
    • Campbell, W. B., Gebremedhin, D., Pratt, P. F., and Harder, D. R. (1996). Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ. Res. 78, 415-423.
    • (1996) Circ. Res. , vol.78 , pp. 415-423
    • Campbell, W.B.1    Gebremedhin, D.2    Pratt, P.F.3    Harder, D.R.4
  • 5
    • 0242285600 scopus 로고    scopus 로고
    • 11 12-epoxyeicosatrienoic acid (11 12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression
    • Falck, J. R., Reddy, L. M., Reddy, Y. K., Bondlela, M., Krishna, U. M., Ji, Y., Sun, J., and Liao, J. K. (2003b). 11,12-epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression. Bioorg. Med. Chem. Lett. 13, 4011-4014.
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 4011-4014
    • Falck, J.R.1    Reddy, L.M.2    Reddy, Y.K.3    Bondlela, M.4    Krishna, U.M.5    Ji, Y.6    Sun, J.7    Liao, J.K.8
  • 7
    • 33845346159 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids, cell signaling and angiogenesis
    • Fleming, I. (2007). Epoxyeicosatrienoic acids, cell signaling and angiogenesis. Prostaglandins Other Lipid Mediat. 82, 60-67.
    • (2007) Prostaglandins Other Lipid Mediat , vol.82 , pp. 60-67
    • Fleming, I.1
  • 8
    • 1542512379 scopus 로고    scopus 로고
    • 14 15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries
    • Gauthier, K. M., Falck, J. R., Reddy, L. M., and Campbell, W. B. (2004). 14,15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries. Pharmacol. Res. 49, 515-524.
    • (2004) Pharmacol. Res. , vol.49 , pp. 515-524
    • Gauthier, K.M.1    Falck, J.R.2    Reddy, L.M.3    Campbell, W.B.4
  • 11
    • 23944460748 scopus 로고    scopus 로고
    • Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases
    • Imig, J. D. (2005). Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases. Am. J. Physiol. Renal Physiol. 289, F496-F503.
    • (2005) Am. J. Physiol. Renal Physiol. , vol.289
    • Imig, J.D.1
  • 13
    • 77958487000 scopus 로고    scopus 로고
    • Compositions and methods for the treatment of renal and cardiovascular disease
    • Cont.-in-part of U.S. Ser. No. 866 395. US 2008153889 A1 20080626 CAN 149 104528 AN 2008 773879
    • Imig, J. D., and Falck, J. R. (2008a). Compositions and methods for the treatment of renal and cardiovascular disease. U.S. Pat. Appl. Publ., Cont.-in-part of U.S. Ser. No. 866,395. US 2008153889 A1 20080626 CAN 149:104528 AN 2008:773879.
    • (2008) U. S. Pat. Appl. Publ.
    • Imig, J.D.1    Falck, J.R.2
  • 14
    • 84866375679 scopus 로고    scopus 로고
    • 11-Nonyloxyundec-8(Z)-enoic acid and derivatives for the treatment of renal and cardiovascular disease
    • US 2008146663 A1 20080619 CAN 149 70453 AN 2008 743378
    • Imig, J. D., and Falck, J. R. (2008b). 11-Nonyloxyundec-8(Z)-enoic acid and derivatives for the treatment of renal and cardiovascular disease. U.S. Pat. Appl. Publ. US 2008146663 A1 20080619 CAN 149:70453 AN 2008:743378.
    • (2008) U. S. Pat. Appl. Publ.
    • Imig, J.D.1    Falck, J.R.2
  • 15
    • 77958487000 scopus 로고    scopus 로고
    • Compositions and methods for the treatment of renal and cardiovascular disease
    • Imig, J. D., and Falck, J. R. (2009). Compositions and methods for the treatment of renal and cardiovascular disease. US Patent #7,550,617.
    • (2009) US Patent , vol.7 , Issue.550 , pp. 617
    • Imig, J.D.1    Falck, J.R.2
  • 16
    • 0032942665 scopus 로고    scopus 로고
    • Afferent arteriolar vasodilation to the sulfonimide analog of 11 12-epoxyeicosatrienoic acid involves protein kinase A
    • Imig, J. D., Inscho, E. W., Deichmann, P. C., Reddy, K. M., and Falck, J. R. (1999). Afferent arteriolar vasodilation to the sulfonimide analog of 11, 12-epoxyeicosatrienoic acid involves protein kinase A. Hypertension 33, 408-413.
    • (1999) Hypertension , vol.33 , pp. 408-413
    • Imig, J.D.1    Inscho, E.W.2    Deichmann, P.C.3    Reddy, K.M.4    Falck, J.R.5
  • 17
    • 0035024260 scopus 로고    scopus 로고
    • Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11 12-epoxyeicosatrienoic acid
    • Imig, J. D., Zhao, X., Falck, J. R., Wei, S., and Capdevila, J. H. (2001). Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. J. Hypertens. 19, 983-992.
    • (2001) J. Hypertens. , vol.19 , pp. 983-992
    • Imig, J.D.1    Zhao, X.2    Falck, J.R.3    Wei, S.4    Capdevila, J.H.5
  • 18
    • 33644654633 scopus 로고    scopus 로고
    • An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in saltsensitive hypertension
    • Imig, J. D., Zhao, X., Zaharis, C. Z., Olearczyk, J. J., Pollock, D. M., Newman, J. W., Kim, I. H., Watanabe, T., and Hammock, B. D. (2005). An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in saltsensitive hypertension. Hypertension 46, 975-981.
    • (2005) Hypertension , vol.46 , pp. 975-981
    • Imig, J.D.1    Zhao, X.2    Zaharis, C.Z.3    Olearczyk, J.J.4    Pollock, D.M.5    Newman, J.W.6    Kim, I.H.7    Watanabe, T.8    Hammock, B.D.9
  • 20
    • 0033588034 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids
    • Node, K., Huo, Y., Ruan, X., Yang, B., Spiecker, M., Ley, K., Zeldin, D. C., and Liao, J. K. (1999). Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science 285, 1276-1279.
    • (1999) Science , vol.285 , pp. 1276-1279
    • Node, K.1    Huo, Y.2    Ruan, X.3    Yang, B.4    Spiecker, M.5    Ley, K.6    Zeldin, D.C.7    Liao, J.K.8
  • 21
    • 0041529844 scopus 로고    scopus 로고
    • 12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by downregulating p27Kip1
    • Potente, M., Fisslthaler, B., Busse, R., and Fleming, I. (2003). 11,12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by downregulating p27Kip1. J. Biol. Chem. 278, 29619-29625.
    • (2003) J. Biol. Chem. , vol.11 , pp. 29619-29625
    • Potente, M.1    Fisslthaler, B.2    Busse, R.3    Fleming, I.4
  • 22
    • 33845290283 scopus 로고    scopus 로고
    • Role of epoxyeicosatrienoic acids protecting the myocardium following ischemia/reperfusion injury
    • Seubert, J. M., Zeldin, D. C., Nithipatikom, K., and Gross, G. J. (2007). Role of epoxyeicosatrienoic acids protecting the myocardium following ischemia/reperfusion injury. Prostaglandins Other Lipid Mediat. 82, 50-59.
    • (2007) Prostaglandins Other Lipid Mediat , vol.82 , pp. 50-59
    • Seubert, J.M.1    Zeldin, D.C.2    Nithipatikom, K.3    Gross, G.J.4
  • 24
    • 0242720683 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function
    • Spector, A. A., Fang, X., Snyder, G. D., and Weintraub, N. L. (2004). Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function. Prog. Lipid Res. 43, 55-90.
    • (2004) Prog. Lipid Res. , vol.43 , pp. 55-90
    • Spector, A.A.1    Fang, X.2    Snyder, G.D.3    Weintraub, N.L.4
  • 25
    • 77950679870 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acid analogs and vascular function
    • Sudhahar, V., Shaw, S., and Imig, J. D. (2010). Epoxyeicosatrienoic acid analogs and vascular function. Curr. Med. Chem. 17, 1181-1190.
    • (2010) Curr. Med. Chem. , vol.17 , pp. 1181-1190
    • Sudhahar, V.1    Shaw, S.2    Imig, J.D.3
  • 26
    • 0037123925 scopus 로고    scopus 로고
    • Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids
    • Sun, J., Sui, X., Bradbury, J. A., Zeldin, D. C., Conte, M. S., and Liao, J. K. (2002). Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids. Circ. Res. 90, 1020-1027.
    • (2002) Circ. Res. , vol.90 , pp. 1020-1027
    • Sun, J.1    Sui, X.2    Bradbury, J.A.3    Zeldin, D.C.4    Conte, M.S.5    Liao, J.K.6
  • 27
    • 0242721221 scopus 로고    scopus 로고
    • Effect of 11 12-epoxyeicosatrienoic acid as an additive to St. Thomas' cardioplegia and University of Wisconsin solutions on endothelium-derived hyperpolarizing factor-mediated function in coronary microarteries: influence of temperature and time
    • Yang, Q., Zhang, R. Z., Yim, A. P., and He, G. W. (2003). Effect of 11,12-epoxyeicosatrienoic acid as an additive to St. Thomas' cardioplegia and University of Wisconsin solutions on endothelium-derived hyperpolarizing factor-mediated function in coronary microarteries: influence of temperature and time. Ann. Thorac. Surg. 76, 1623-1630.
    • (2003) Ann. Thorac. Surg. , vol.76 , pp. 1623-1630
    • Yang, Q.1    Zhang, R.Z.2    Yim, A.P.3    He, G.W.4
  • 28
    • 34248570494 scopus 로고    scopus 로고
    • Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14 15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding
    • Yang, W., Holmes, B. B., Gopal, V. R., Kishore, R. V., Sangras, B., Yi, X. Y., Falck, J. R., and Campbell, W. B. (2007). Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding. J. Pharmacol. Exp. Ther. 321, 1023-1031.
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 1023-1031
    • Yang, W.1    Holmes, B.B.2    Gopal, V.R.3    Kishore, R.V.4    Sangras, B.5    Yi, X.Y.6    Falck, J.R.7    Campbell, W.B.8
  • 29
    • 0035965327 scopus 로고    scopus 로고
    • Epoxygenase pathways of arachidonic acid metabolism
    • Zeldin, D. C. (2001). Epoxygenase pathways of arachidonic acid metabolism. J. Biol. Chem. 276, 36059-36062.
    • (2001) J. Biol. Chem. , vol.276 , pp. 36059-36062
    • Zeldin, D.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.