-
1
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis SN, Fletcher JI, Kaufmann T, et al. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science, 2007, 315:856-859.
-
(2007)
Science
, vol.315
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
-
2
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
DOI 10.1038/sj.onc.1210220, PII 1210220
-
Adams JM, Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene, 2007, 26:1324-1337. (Pubitemid 46328466)
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
3
-
-
66049119756
-
ABT-737 synergizes with chemotherapy to kill head and neck squamous cell carcinoma cells via a Noxa-mediated pathway
-
Li R, Zang Y, Li C, et al. ABT-737 synergizes with chemotherapy to kill head and neck squamous cell carcinoma cells via a Noxa-mediated pathway. Mol Pharmacol, 2009, 75:1231-1239.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1231-1239
-
-
Li, R.1
Zang, Y.2
Li, C.3
-
4
-
-
77957954881
-
The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib
-
Hikita H, Takehara T, Shimizu S, et al. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib. Hepatology, 2010, 52:1310-1321.
-
(2010)
Hepatology
, vol.52
, pp. 1310-1321
-
-
Hikita, H.1
Takehara, T.2
Shimizu, S.3
-
5
-
-
77958591155
-
Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells
-
Lieber J, Kirchner B, Eicher C, et al. Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells. Pediatr Blood Cancer, 2010, 55:1089-1095.
-
(2010)
Pediatr Blood Cancer
, vol.55
, pp. 1089-1095
-
-
Lieber, J.1
Kirchner, B.2
Eicher, C.3
-
6
-
-
70450265383
-
The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia
-
Mason KD, Khaw SL, Rayeroux KC, et al. The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia. Leukemia, 2009, 23:2034-2041.
-
(2009)
Leukemia
, vol.23
, pp. 2034-2041
-
-
Mason, K.D.1
Khaw, S.L.2
Rayeroux, K.C.3
-
7
-
-
33845365078
-
Gemcitabine and cisplatin combination chemotherapy as a first-line treatment in patients with metastatic breast cancer
-
Mohran TZ. Gemcitabine and cisplatin combination chemotherapy as a first-line treatment in patients with metastatic breast cancer. J Egypt Natl Canc Inst, 2004, 16:8-14.
-
(2004)
J Egypt Natl Canc Inst
, vol.16
, pp. 8-14
-
-
Mohran, T.Z.1
-
8
-
-
65549094094
-
Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer
-
Chew HK, Doroshow JH, Frankel P, et al. Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer. J Clin Oncol, 2009, 27:2163-2169.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2163-2169
-
-
Chew, H.K.1
Doroshow, J.H.2
Frankel, P.3
-
9
-
-
14844354794
-
First-line chemotherapy with docetaxel and cisplatin in metastatic breast cancer
-
DOI 10.1016/j.breast.2004.08.017, PII S0960977604001730
-
Vassilomanolakis M, Koumakis G, Barbounis V, et al. First-line chemotherapy with docetaxel and cisplatin in metastatic breast cancer. Breast, 2005, 14:136-141. (Pubitemid 40353041)
-
(2005)
Breast
, vol.14
, Issue.2
, pp. 136-141
-
-
Vassilomanolakis, M.1
Koumakis, G.2
Barbounis, V.3
Demiri, M.4
Panopoulos, C.5
Chrissohoou, M.6
Apostolikas, N.7
Efremidis, A.P.8
-
10
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
DOI 10.1038/sj.onc.1206933, Drug Resistance
-
Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene, 2003, 22:7265-7279. (Pubitemid 37487159)
-
(2003)
Oncogene
, vol.22
, Issue.47 REV. ISS. 6
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
11
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
DOI 10.1038/nature03579
-
Oltersdorf T, Elmore SW, Shoemaker AR, et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature, 2005, 435:677-681. (Pubitemid 40825512)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
-
12
-
-
42049104916
-
Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer
-
DOI 10.1158/0008-5472.CAN-07-5031
-
Hann CL, Daniel VC, Sugar EA, et al. Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer. Cancer Res, 2008, 68:2321-2328. (Pubitemid 351521806)
-
(2008)
Cancer Research
, vol.68
, Issue.7
, pp. 2321-2328
-
-
Hann, C.L.1
Daniel, V.C.2
Sugar, E.A.3
Dobromilskaya, I.4
Murphy, S.C.5
Cope, L.6
Lin, X.7
Hierman, J.S.8
Wilburn, D.L.9
Watkins, D.N.10
Rudin, C.M.11
-
13
-
-
41349123507
-
BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia
-
DOI 10.1182/blood-2007-06-098012
-
Del Gaizo Moore V, Schlis KD, Sallan SE, et al. BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia. Blood, 2008, 111:2300-2309. (Pubitemid 351451437)
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 2300-2309
-
-
Del, G.M.V.1
Schlis, K.D.2
Sallan, S.E.3
Armstrong, S.A.4
Letai, A.5
-
14
-
-
34250770481
-
ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells
-
DOI 10.1038/sj.leu.2404719, PII 2404719
-
Kline MP, Rajkumar SV, Timm MM, et al. ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells. Leukemia, 2007, 21:1549-1560. (Pubitemid 46965297)
-
(2007)
Leukemia
, vol.21
, Issue.7
, pp. 1549-1560
-
-
Kline, M.P.1
Rajkumar, S.V.2
Timm, M.M.3
Kimlinger, T.K.4
Haug, J.L.5
Lust, J.A.6
Greipp, P.R.7
Kumar, S.8
-
15
-
-
33646354381
-
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
-
DOI 10.1016/j.ccr.2006.03.027, PII S1535610806001139
-
Certo M, Del Gaizo Moore V, Nishino M, et al. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell, 2006, 9:351-365. (Pubitemid 43668734)
-
(2006)
Cancer Cell
, vol.9
, Issue.5
, pp. 351-365
-
-
Certo, M.1
Moore, V.D.G.2
Nishino, M.3
Wei, G.4
Korsmeyer, S.5
Armstrong, S.A.6
Letai, A.7
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