The combined ratios of L-arginine and asymmetric and symmetric dimethylarginine as biomarkers in spontaneously hypertensive rats

Translational Research

Volumn 159, Issue 2, 2012, Pages 90-98

  Hsu, Chien Ning ^a,b,c   Huang, Li Tung ^a,b,c   Lau, Ying Tung ^a,b,c   Lin, Ching Yuang ^a,b,c   Tain, You Lin ^a,b,c,d  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

6 N,N' DIMETHYLARGININE; ARGININE; BIOLOGICAL MARKER; DIMETHYLARGININASE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; DISEASE ACTIVITY; DISEASE COURSE; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

EID: 84862949346     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2011.09.002     Document Type: Article

References (22)

1. C.S. Wilcox Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension? Am J Physiol Regul Integr Comp Physiol 89 2005 R913 R935 (Pubitemid 41397037)
2. J. Török Participation of nitric oxide in different models of experimental hypertension Physiol Res 57 2008 813 825
3. C. Baylis Arginine, arginine analogs and nitric oxide production in chronic kidney disease Nat Clin Pract Nephrol 2 2006 209 220 (Pubitemid 43787287)
4. T. Teerlink, Z. Luo, F. Palm, and C.S. Wilcox Cellular ADMA: regulation and action Pharmacol Res 60 2009 448 460
5. Y.L. Tain, and L.T. Huang Asymmetric dimethylarginine: clinical application in pediatric medicine J Formos Med Assoc 110 2011 70 77
6. J.T. Kielstein, S.R. Salpeter, S.M. Bode-Boeger, J.P. Cooke, and D. Fliser Symmetric dimethylarginine (SDMA) as endogenous marker of renal function - a meta-analysis Nephrol Dial Transplant 21 2006 2446 2451 (Pubitemid 44644516)
7. S.M. Bode-Boger, F. Scalera, and L.J. Ignarro The l-arginine paradox: importance of the l-arginine/asymmetrical dimethylarginine ratio Pharmacol Ther 114 2007 295 306 (Pubitemid 46843253)
8. Y.M. Pinto, M. Paul, and D. Ganten Lessons from rat models of hypertension: from Goldblatt to genetic engineering Cardiovasc Res 39 1998 77 88 (Pubitemid 28322381)
9. K. Uchino, E.D. Frohlich, T. Nishikimi, T. Isshiki, and M.B. Kardon Spontaneously hypertensive rats demonstrate increased renal vascular alpha 1-adrenergic receptor responsiveness Am J Physiol 260 1991 R889 R893
10. A. Numabe, K. Komatsu, and E.D. Frohlich Effects of ANG-converting enzyme and alpha1-adrenoceptor inhibition on intrarenal hemodynamics in SHR Am J Physiol 266 1994 R1437 R1442
11. Y.L. Tain, L.T. Huang, I.C. Lin, Y.T. Lau, and C.Y. Lin Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats J Pineal Res 49 2010 390 398
12. R.H. Böger The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor Cardiovasc Res 59 2003 824 833 (Pubitemid 38366238)
13. J. Jacobi, and P.S. Tsao Asymmetrical dimethylarginine in renal disease: limits of variation or variation limits? A systematic review Am J Nephrol 28 2008 224 237
14. G. Iapichino, M. Umbrello, and M. Albicini Time course of endogenous nitric oxide inhibitors in severe sepsis in humans Minerva Anestesiol 76 2010 325 333
15. Y.L. Tain, G. Freshour, A. Dikalova, K. Griendling, and C. Baylis Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat Am J Physiol Renal Physiol 292 2007 F1404 F1410 (Pubitemid 46701867)
16. Y.L. Tain, and C. Baylis Determination of dimethylarginine dimethylaminohydrolase activity in the kidney Kidney Int 72 2007 886 889 (Pubitemid 47462078)
17. Y.L. Tain, C.S. Hsieh, and I.C. Lin Effects of maternal L-citrulline supplementation on renal function and blood pressure in offspring exposed to maternal caloric restriction: the impact of nitric oxide pathway Nitric Oxide 23 2010 34 41
18. A.M. Verhagen, H.A. Koomans, and J.A. Joles Predisposition of spontaneously hypertensive rats to develop renal injury during nitric oxide synthase inhibition Eur J Pharmacol 411 2001 175 180 (Pubitemid 32013126)
19. L.G. Feld, J.B. Van Liew, R.G. Galaske, and J.W. Boylan Selectivity of renal injury and proteinuria in the spontaneously hypertensive rat Kidney Int 12 1977 332 343 (Pubitemid 8249780)
20. Y. Matsumoto, S. Ueda, and S. Yamagishi Dimethylarginine dimethylaminohydrolase prevents progression of renal dysfunction by inhibiting loss of peritubular capillaries and tubulointerstitial fibrosis in a rat model of chronic kidney disease J Am Soc Nephrol 18 2007 1525 1533 (Pubitemid 46717519)
21. Z. Luo, T. Teerlink, and K. Griendling Angiotensin II and NADPH oxidase increase ADMA in vascular smooth muscle cells Hypertension 56 2010 498 504
22. M.B. Moss, T.M. Brunini, and R. Soares De Moura Diminished L-arginine bioavailability in hypertension Clin Sci (Lond) 107 2004 391 397 (Pubitemid 39389306)