High-dose insulin therapy reduces postoperative liver dysfunction and complications in liver resection patients through reduced apoptosis and altered inflammation

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 1, 2012, Pages 217-226

  Fisette, Alexandre ^a   Hassanain, Mazen ^b,c   Metrakos, Peter ^b,c   Doi, Suhail A R ^d   Salman, Ayat ^c   Schricker, Thomas ^b   Lattermann, Ralph ^b   Wykes, Linda ^b   Nitschmann, Evan ^b   Smith, Jessica ^a   Cianflone, Katherine ^a  

^a LAVAL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; C REACTIVE PROTEIN; FATTY ACID; FRUCTOSE 1,6 BISPHOSPHATE; GLUCAGON; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; INSULIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIVER ENZYME; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ADULT; APOPTOSIS; ARTICLE; CARBOHYDRATE INTAKE; CELL DEATH; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; FATTY ACID BLOOD LEVEL; FEMALE; GENE EXPRESSION; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLYCEMIC CONTROL; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; INFECTION; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN TREATMENT; INTERMETHOD COMPARISON; LIVER BIOPSY; LIVER CELL; LIVER DYSFUNCTION; LIVER FUNCTION; LIVER RESECTION; MALE; POSTOPERATIVE COMPLICATION; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; RANDOMIZED CONTROLLED TRIAL; RISK REDUCTION;

AGED; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FEMALE; GLUCOSE CLAMP TECHNIQUE; HEPATECTOMY; HEPATITIS; HUMANS; INFLAMMATION; INSULIN; LIVER; LIVER DISEASES; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; STANDARD OF CARE;

EID: 84862947490     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-1598     Document Type: Article

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