Optimization of pyruvate production conditions based on environmental adaptability of torulopsis glabrata in a pilot plant scale

Guocheng Gongcheng Xuebao/The Chinese Journal of Process Engineering

Volumn 11, Issue 6, 2011, Pages 1044-1049

  Yang, Song Xin ^a   Wang, Meng ^a   Wang, Jun ^a   Liu, Li Ming ^a   Chen, Jian ^a  

^a JIANGNAN UNIVERSITY   (China)

Author keywords

Environmental adaptability; Fermentation optimization; Pyruvate; Torulopsis glabrata

Indexed keywords

EID: 84862946016     PISSN: 1009606X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Causey T B, Shanmugam K T, Yomano L P, et al. Engineering Escherichia coli for Efficient Conversion of Glucose to Pyruvate [J]. Proceedings of the National Academy of Sciences, 2004, 101: 2235-2240.
2. Wang Q H, He P, Lu D J, et al. Metabolic Engineering of Torulopsis glabrata for Improved Pyruvate Production [J]. Enzyme Microb. Technol., 2005, 36: 832-839.
3. 2002, 18(6): 651-655.
4. Garcia-Ochoa F, Gomez E. Bioreactor Scale-up and Oxygen Transfer Rate in Microbial Processes: An Overview [J]. Biotechnol. Adv., 2009, 27(2): 153-176.
5. García-Camacho F, Gallardo-Rodríguez J J, Sánchez Mirón A, et al. Determination of Shear Stress Thresholds in Toxic Dinoflagellates Cultured in Shaken Flasks: Implications in Bioprocess Engineering [J]. Process Biochem., 2007, 42(11): 1506-1515.
6. Schmidt F R. Optimization and Scale up of Industrial Fermentation Processes [J]. Appl. Microbiol. Biotechnol., 2005, 68(4): 425-435.
7. 2004, 20(1): 115-119.
8. 2001, 31(2): 10-13.
9. 2000, 40(5): 528-534.
10. Li Y, Hugenholtz J, Chen J, et al. Enhancement of Pyruvate Production by Torulopsis glabrata Using a Two-stage Oxygen Supply Control Strategy [J]. Appl. Microbiol. Biotechnol., 2002, 60(1/2): 101-106.
11. 2006, 25(10): 1128-1133.
12. 2002, 32(3): 10-14.
13. Liu L M, Li Y, Li H Z, et al. Manipulating the Pyruvate Dehydrogenase Bypass of A Multi-vitamin Auxotrophic Yeast Torulopsis glabrata Enhanced Pyruvate Production [J]. Lett. Appl. Microbiol., 2004, 39: 199-206.
14. Liu L M, Li Y, Zhu Y, et al. Redistribution of Carbon Flux in Torulopsis glabrata by Altering Vitamin and Calcium Level [J]. Metab. Eng., 2007, 9(1): 21-29.
15. Miller G L. Use of Dinitrosalicylic Acid Reagent for Determination of Reducing Sugar [J]. Anal. Chem., 1959, 3(3): 426-428.
16. Liu L M, Li Y, Du G C, et al. Increasing Glycolytic Flux in Torulopsis glabrata by Redirecting ATP Production from Oxidative Phosphorylation to Substrate-level Phosphorylation [J]. J. Appl. Microbiol., 2006, 100(5): 1043-1053.
17. Pronk J T. Pyruvate Metabolism in Saccharomyces cerevisiae [J]. Yeast, 1996, 12(9): 1607-1633.
18. + Availability [J]. J. Biotech., 2006, 126(2): 173-185.