Synthesis and biological evaluation of 4α/4β-imidazolyl podophyllotoxin analogues as antitumor agents

Archiv der Pharmazie

Volumn 345, Issue 1, 2012, Pages 43-48

  Shang, Hai ^a   Chen, Hong ^b   Zhao, Dongmei ^a   Tang, Xiaowei ^b   Liu, Yongfeng ^b   Pan, Li ^a   Cheng, Maosheng ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b MEDICAL COLLEGE OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

Cancer cell lines; Cytotoxicity; Multidrug resistance; Podophyllotoxin

Indexed keywords

4 ALPHA (2 METHYL 1H IMIDAZOL 1 YL) 4 DESOXYPODOPHYLLOTOXIN; 4 ALPHA (4 METHYL 1H IMIDAZOL 1 YL) 4 DESOXYPODOPHYLLOTOXIN; 4 BETA (1H IMIDAZOL 1 YL) 4 DESOXYPODOPHYLLOTOXIN; 4 BETA (4 NITRO 1H IMIDAZOL 1 YL) 4 DESOXYPODOPHYLLOTOXIN; 4' O DEMETHYL 4 BETA (4 NITRO 1H IMIDAZOL 1 YL) 4 DESOXYPODOPHYLLOTOXIN; 4' O DEMETHYL 4B (2 METHYL 5 NITRO 1H IMIDAZOL 1 YL) 4 DESOXYPODOPHYLLOTOXIN; ANTINEOPLASTIC AGENT; N BETA (2 METHYL 5 NITRO 1H IMIDAZOL 1 YL) 4 DESOXYPODOPHYLLOTOXIN; PODOPHYLLOTOXIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL STRAIN K 562; CYTOTOXICITY; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DESIGN; HUMANS; IMIDAZOLES; INHIBITORY CONCENTRATION 50; K562 CELLS; MOLECULAR STRUCTURE; PODOPHYLLOTOXIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862935796     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201100094     Document Type: Article

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