Design, synthesis, and biological testing of 4β-[(4-substituted)-1,2, 3-triazol-1-yl]podophyllotoxin analogues as antitumor agents

Archiv der Pharmazie

Volumn 341, Issue 2, 2008, Pages 126-131

  Reddy, Pitta B ^a   Paul, David V ^a   Agrawal, Satyam K ^a   Saxena, Ajit K ^a   Kumar, Halmuthur M S ^a   Qazi, Ghulam N ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Copper(I); Cycloaddition; Podophyllotoxin; Regio selectivity

Indexed keywords

1 O PROPARGYL MONOSACCHARIDE; 4BETA (1,2,3 TRIAZOL 1 YL)PODOPHYLLOTOXIN DERIVATIVE; ANTINEOPLASTIC AGENT; C 4BETA AZIDO 4' O NORPODOPHYLLOTOXIN; C 4BETA AZIDOPODOPHYLLOTOXIN; COPPER; ETOPOSIDE; MONOSACCHARIDE; PODOPHYLLOTOXIN DERIVATIVE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; PODOPHYLLOTOXIN; TRIAZOLE DERIVATIVE;

ARTICLE; CANCER CELL; CELL LINE; COLON; CONTROLLED STUDY; CYCLOADDITION; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE; SUBSTITUTION REACTION; CHEMISTRY; DRUG SCREENING; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PODOPHYLLOTOXIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 43149126598     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200700116     Document Type: Article

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